Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    A safety and pharmacokinetic dosing study of glucagon-like peptide 2 in infants with intestinal failure

    Sigalet, D. L., Brindle, M. E., Boctor, D., Dicken, B., Lam, V., Lu, L. S., de Heuvel, E., Hartmann, Bolette & Holst, Jens Juul, 29 Jan 2017, In: Journal of Pediatric Surgery. 52, 5, p. 749-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells

    Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sturla, L., Sociali, G., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2017, In: European Journal of Clinical Investigation. 47, p. 112-113

    Research output: Contribution to journal › Conference abstract in journal › Research

  4. Published

    Acute effects of glucagon-like peptide-1, GLP-19-36 amide, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers

    Hansen, Lasse Bremholm, Andersen, U. B., Hornum, Mads, Hilsted, L., Veedfald, S., Hartmann, Bolette & Holst, Jens Juul, Feb 2017, In: Physiological Reports. 5, 4, 12 p., e13102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: A randomized controlled trial in patients with type 2 diabetes

    Nauck, M. A., Kahle, M., Baranov, O., Deacon, Carolyn F. & Holst, Jens Juul, 6 Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 200-207 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Addition of rye bran and pea fiber to pork meatballs enhances subjective satiety in healthy men, but does not change glycemic or hormonal responses: A randomized crossover meal test study

    Kehlet, U., Kofod, J., Holst, Jens Juul, Ritz, C., Aaslyng, M. D. & Raben, Anne, 2017, In: Journal of Nutrition. 147, 9, p. 1700-1708 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

    Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

    Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, Jens Juul, Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C. & Blaak, E. E., 24 May 2017, In: Scientific Reports. 7, 12 p., 2360.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

    Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes

    Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity

    Böhm, A., Wagner, R., Machicao, F., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A., Häring, H. & Staiger, H., 2017, In: PloS one. 12, 7, 13 p., e0181880.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Defects in α-Cell Function in Patients With Diabetes Due to Chronic Pancreatitis Compared With Patients With Type 2 Diabetes and Healthy Individuals

    Mumme, L., Breuer, T. G. K., Rohrer, S., Schenker, N., Menge, B. A., Holst, Jens Juul, Nauck, M. A. & Meier, J. J., Oct 2017, In: Diabetes Care. 40, 10, p. 1314-1322 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects

    Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Discovery, characterization, and clinical development of the glucagon-like peptides

    Drucker, D. J., Habener, J. F. & Holst, Jens Juul, 1 Dec 2017, In: The Journal of Clinical Investigation. 127, 12, p. 4217-4227 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Effect of GLP-1 Receptor Agonist Treatment on Body weight in Obese Antipsychotic-treated Patients with Schizophrenia: a Randomized, Placebo-controlled Trial Byline

    Ishøy, P. L., Knop, Filip Krag, Broberg, B. V., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, Jens Juul, Glenthøj, Birte Yding & Ebdrup, Bjørn, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 162-171

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of Liraglutide Treatment on Prediabetes and Overweight or Obesity in Clozapine- or Olanzapine-Treated Patients With Schizophrenia Spectrum Disorder: A Randomized Clinical Trial

    Larsen, J. R., Vedtofte, L., Jakobsen, M. S. L., Jespersen, H. R., Jakobsen, M. I., Svensson, C. K., Koyuncu, K., Schjerning, O., Oturai, P. S., Kjær, Andreas, Nielsen, J., Holst, Jens Juul, Ekstrøm, Claus Thorn, Correll, C. U., Vilsbøll, Tina & Fink-Jensen, Anders, 1 Jul 2017, In: J A M A Psychiatry. 74, 7, p. 719-728 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effect of oral contraceptives and/or metformin on GLP-1 secretion and reactive hypoglycaemia in polycystic ovary syndrome

    Glintborg, D., Mumm, H., Holst, Jens Juul & Andersen, M., May 2017, In: Endocrine Connections. 6, 4, p. 267-277 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats

    Lai, S. W., de Heuvel, E., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Brindle, M. E., Chelikani, P. K. & Sigalet, D. L., 2017, In: PloS one. 12, 7, 20 p., e0181453.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues

    Ten Kulve, J. S., Veltman, D. J., Gerdes, V. E. A., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M. & IJzerman, R. G., Nov 2017, In: Diabetes Care. 40, 11, p. 1522-1529 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men

    Matikainen, N., Söderlund, S., Björnson, E., Bogl, L. H., Pietiläinen, K. H., Hakkarainen, A., Lundbom, N., Eliasson, B., Räsänen, S. M., Rivellese, A., Patti, L., Prinster, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., Jun 2017, In: Nutrition, Metabolism & Cardiovascular Diseases. 27, 6, p. 534-542 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release

    wbf943, wbf943, Gabe, M. N., Gasbjerg, Lærke Smidt, Christiansen, Charlotte Bayer, Svendsen, B., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2017, In: Biochemical Pharmacology. 131, p. 78-88

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genetic determinants of circulating GIP and GLP-1 concentrations

    Almgren, P., Lindqvist, A., Krus, U., Hakaste, L., Ottosson-Laakso, E., Asplund, O., Sonestedt, E., Prasad, R. B., Laurila, E., Orho-Melander, M., Melander, O., Tuomi, T., Holst, Jens Juul, Nilsson, P. M., Wierup, N., Groop, L. & Ahlqvist, E., 2 Nov 2017, In: JCI insight. 2, 21, 13 p., e93306.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Glucagon and Amino Acids Are Linked in a Mutual Feedback Cycle: The Liver-α-Cell Axis

    Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens & Knop, Filip Krag, Feb 2017, In: Diabetes. 66, 2, p. 235-240 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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