Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans

    Meier, J. J., Gethmann, A., Götze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Mar 2006, In: Diabetologia. 49, 3, p. 452-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, Lindley, K. J. & O'Rahilly, S., Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Impact of cereal fibre on glucose-regulating factors

    Weickert, M. O., Mohlig, M., Koebnick, C., Holst, Jens Juul, Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J. & Pfeiffer, A. F. H., Nov 2005, In: Diabetologia. 48, 11, p. 2343-53 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Feast or famine - are GLP-1 and ghrelin secretion intertwined?

    Djurhuus, C. B., Hansen, T. K., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 353-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., Jul 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Incretin effect after oral amino Acid ingestion in humans

    Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors

    Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine

    Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Incretins, insulin secretion and Type 2 diabetes mellitus

    Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects

    Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes

    Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2719-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit

    Larsen, P. J., Seier, V., Fink-Jensen, Anders, Holst, Jens Juul, Warberg, J. & Vrang, N., Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 219-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, Cathrine, Jansen-Olesen, I., Chiarelli, F., Holst, Jens Juul, Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B. & Hansen, L., Jun 2007, In: European Journal of Endocrinology. Supplement. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A 25-year-old woman with type 2 diabetes and liver disease

    Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    GLP-2 levels in infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartman, B. & Holst, Jens Juul, Sep 2004, In: Pediatric Research. 56, 3, p. 371-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers

    Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Ritzel, R., Hüfner, M. & Schmiegel, W. H., Mar 2002, In: The Journal of clinical endocrinology and metabolism. 87, 3, p. 1239-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Gastric inhibitory polypeptide does not inhibit gastric emptying in humans

    Meier, J. J., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., Apr 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 286, 4, p. E621-5

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia

    Mulla, C. M., Goldfine, A. B., Dreyfuss, J. M., Houten, S., Pan, H., Pober, D. M., Albrechtsen, Nicolai Jacob Wewer, Svane, M. S., Schmidt, J. B., Holst, Jens Juul, Craig, C. M., McLaughlin, T. L. & Patti, M., 2019, In: Obesity Surgery. 29, 7, p. 2092-2099

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

    Muller, M., Hernandez, M. A. G., Goossens, G. H., Reijnders, D., Holst, Jens Juul, Jocken, J. W. E., van Eijk, H., Canfora, E. E. & Blaak, E. E., 2019, In: Scientific Reports. 9, 9 p., 12515.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition

    Haedersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, p. S312-S312.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Gut-derived glucagon in man: [Meeting Abstract]

    Baekdal, M., Lund, A., Albrechtsen, Nicolai Jacob Wewer, Egholk, J., Jorsal, T., Black-Juel, C. T., Dal, Jenna Elizabeth Hunt, Galsgaard, Katrine Douglas, Rigbolt, K., Palnaes, C., Ørskov, Cathrine, Poulsen, Steen Seier, Holst, Jens Juul, Villsboll, T. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 472.

    Research output: Contribution to journalConference abstract in journalResearch

  28. Published

    Liraglutide preserved insulin secretion in adults with newly diagnosed type 1 diabetes: the NewLira trial: [Meeting Abstract}

    Dejgaard, T. F., Frandsen, C., Kielgast, U., Andersen, H. U., Thorsteinsson, B., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S75-S75 145.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized Single-Blinded Placebo Controlled Study

    Behary, P., Tharakan, G., Alexiadou, K., Johnson, N., Albrechtsen, N. J. W., Kenkre, J., Cuenco, J., Hope, D., Anyiam, O., Choudhury, S., Alessimii, H., Poddar, A., Minnion, J., Doyle, C., Frost, G., Le Roux, C., Purkayastha, S., Moorthy, K., Dhillo, W., Holst, J. J. & 4 others, Ahmed, A. R., Prevost, A. T., Bloom, S. R. & Tan, T. M., 2019, In: Diabetes Care. 42, 7, 8 p., dc190449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Glucagon Receptor Signaling and Lipid Metabolism

    Galsgaard, Katrine Douglas, Pedersen, Jens, Knop, Filip Krag, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: Frontiers in Physiology. 10, 11 p., 413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial

    fbg982, fbg982, Samkani, A., Petersen, A. D., Thomsen, M. N., Astrup, A., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Larsen, T. M., Haugaard, Steen Bendix & Krarup, T., 2019, In: Diabetologia. 62, 11, p. 2066-2078 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas

    Larsen, M. O., Rolin, B., Gotfredsen, C. F., Carr, R. D. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 1873-1878

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Teduglutide (ALX-0600), a dipeptidyl-peptidase-IV resistant glucagon-like-2 analog improves intestinal function in short bowel syndrome patients

    Jeppesen, P. B., Sanguinetti, E. L., Buckman, A., Howard, L., Scolapio, J. S., Ziegler, T. R., Gregory, M., Tappendent, K. A., Holst, Jens Juul & Mortensen, P. B., 2005, In: Gut. 54, p. 1224-1231

    Research output: Contribution to journalJournal articleResearch

  35. Published

    GLP-2 levels in human infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartmann, B. & Holst, Jens Juul, 2004, In: Pediatric Research. 56, p. 371-376

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Insulin secretion and incretin hormones after oral glucose in impaired glucose tolerance

    Rask, E., Olsson, T., Söderberg, S., Holst, Jens Juul, Tura, A., Pacini, G. & Ahren, B., 2004, In: Metabolism. 53, p. 624-631

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs

    Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 2004, In: J Parenter Enteral Nutr. 28, p. 210-223

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors

    Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., 2004, In: Diabetes. 53, p. 1326-1335

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome

    Gebhard, B., Holst, Jens Juul & Biegelmayer, C., 2001, In: Digest Dis Sci. 46, p. 1915-1923

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes

    Meier, J. J., Huking, K., Holst, Jens Juul, Deacon, Carolyn F., Schmiegel, W. H. & Nauck, M. A., 2001, In: Diabetes. 50, p. 2497-2504

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Gastric myoelectrical activity and gut hormone secretion in myotonic dystrophy

    Ronnblom, A., Hellstrom, P. M. & Holst, Jens Juul, 2001, In: Eur J Gastroen Hepat. 13, p. 825-831

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Determinants of the effectiveness of glucagon-like peptide- 1 in type 2 diabetes

    Toft-Nielsen, M. B., Madsbad, S. & Holst, Jens Juul, 2001, In: J Clin Endocr Metab. 86, p. 3853-3860

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    GLP-1 inhibits gastric emptying of water but does not influence plasma vasopressin, sodium, or osmolality

    Naslund, E., Bogefors, J., Gryback, P. & Holst, Jens Juul, 2001, In: Scand J Gastroentero. 36, p. 156-162

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Regulatory peptides of the gastrointestinal tract

    Holst, Jens Juul, 2000, Small Bowel Disorders. London: Small Bowel Disorders, p. 96-115

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  45. Published

    Short-term treatment with GLP-1 increases pulsatile secretion in type 2 diabetes with no effect on orderliness.

    Juhl, C. B., Schmitz, O., Holst, Jens Juul, Vedhuis, J. & Pørksen, N., 2000, In: Diabetologia. 43, p. 583-588

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Increased intensity of physical activity stimulates subsequent fat intake

    Klausen, B., Toubro, S., Ranneries, C., Rehfeld, J. F., Holst, Jens Juul, Christensen, N. J. & Astrup, A., 1999, In: International Journal of Obesity. 23, p. 1282-1287

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets

    Goudoever, V., Stoll, B., Hartmann, B., Holst, Jens Juul, Reeds, P. J. & Burrin, D. G., 2001, In: J Nutr.. 131, p. 729-732

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans

    Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Advances in non-peptide glucagon receptor antagonist

    Madsen, P., Knudsen, L. B., Brand, C. L. & Holst, Jens Juul, 1999, In: Curr. Pharm Design. 5, p. 683-691

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Glucagon-like peptide-1 slows solid gastric emptying and inhibits insulin, glucagon and peptide YY release in humans

    Näslund, E., Bogefors, J., Skogar, S., Grybäck, P., Jacobsen, H. L., Holst, Jens Juul & Helström, P. M., 1999, In: Am. J. Physiol.. 277, p. 910-916

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats

    Balkan, B., Kwasnik, L., Miserendino, R., Holst, Jens Juul & Lie, X., 1999, In: Diabetologia. 42, p. 1324-1331

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin

    Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: J. Clin. Invest.. 102, p. 764-774

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure

    Nauck, M. A., Sauerwald, A., Ritzel, R., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetes Care. 21, p. 1925-1931

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying

    Naslund, E., Gryback, P., Backman, L., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 945-952

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

    Holst, Jens Juul, Gromada, K. & Rorsman, P., 1998, In: Pflugers Arch.. 435, p. 583-594

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Regulatory Peptides of the Gut

    Holst, Jens Juul, 1998, Small Bowel Disorders. Kluwer Academic Publishers

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  57. Published

    Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance.

    Christiansen, E., Tibell, A., Vølund, A., Holst, Jens Juul, Rasmussen, K., Schäffer, L. & Madsbad, S., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 2299-2307

    Research output: Contribution to journalJournal articleResearch

  58. Published

    Pituitary adenylate-cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans.

    Filipson, K., Tornøe, K., Holst, Jens Juul & Ahrén, B., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 3093-3098

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.

    Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships

    Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Human Glucagon-like peptide-1, - six important topics.

    Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  62. Published

    The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.

    Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  64. Published

    Sympathoadrenal regulation of adrenal androstenedione release

    Ehrhart-Bornstein, M., Bornstein, S. R., Behling, H. G., Holst, Jens Juul, Strohmayer, H. G., Rasmussen, T. N., Scherbaum, W. A. & Adler, G., 1994, In: Neuroendocrinology. 59, p. 406-412

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Atrial natriuretic peptide-like immunoreactive material (ANP-L1) is released from the adrenal gland by splanchnic nerve stimulation

    Duntas, L., Bornstein, S. R., Scherbaum, W. & Holst, Jens Juul, 1994, In: Exp.Clin.Endocrinol.. 101, p. 371-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Neural regulation of pancreatic exocrine funktion

    Holst, Jens Juul, 1993, In: The Pancreas: Biology, Pathobiology an Disease. p. 381-402

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Characterization of immunoactive pancreastatin in porcine tissues

    Børglum, T. D., Holst, Jens Juul & Fahrenkrug, J., 1991, In: Scand. J. Clin. Lab. Invest.. 51, p. 681-691

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction

    Schjoldager, B., Poulsen, S. S., Schmidt, P., Coy, D. H. & Holst, Jens Juul, Apr 1991, In: American Journal of Physiology (Consolidated). 260, 4 Pt 1, p. G577-85

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP), but not galanin, are autonomic cotransmitters in the porcine pancreas

    Messell, T., Dunning, B. E., Sheikh, S. & Holst, Jens Juul, 1991, In: International Journal of Gastrointestinal Cancer. 10, p. 133-141

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Chap.10. Degradation of glucagons

    Holst, Jens Juul, 1991, Degradation of Bioactive Substances: Physiology and Pathophysiology. Boca Raton, Florida: CRC Press, p. 167-180

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  72. Published

    All products of proglucagon are elevated in plasma from ureamic patients

    Ørskov, Cathrine, Andreasen, J. & Holst, Jens Juul, 1992, In: Journal of Clinical Endocrinology and Metabolism. 79, p. 379-383

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Somostatin and Prosomatostatin-immunoreactive nerve fibers in the bovine pineal gland

    Møller, M., Mikkelsen, J. D. & Holst, Jens Juul, 1992, In: Neuroendocrinology. Vol. 56 (2), p. 278-283

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Neutral Endopeptidase 24.11 and dipeptidyl peptidase IV are both physiological mediators of the degradation of glucagon-like peptide-1 in the anaesthetized pig

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 1882-1890

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome

    Liu, X. W., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2006, In: American Journal of Clinical Nutrition. 84, 5, p. 1142-1150 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes

    Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Glucagon-like peptide-1 suppresses energy expenditure in obese humans

    Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1999, International journal of obesity. Després, J-P. & Macdonald, I. (eds.). 23 ed. European Association for the Study of Obesity, p. S35 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  78. Published

    Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women

    Raben, A., Holst, Jens Juul, Madsen, J. & Astrup, A., 2001, In: American Journal of Clinical Nutrition. 73, p. 177-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Glucagon-like peptide 2 stimulates small-intestine growth and maturation in the pig fetus and neonate

    Petersen, Y. M., Burrin, D. G., Schmidt, M., Elnif, J., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 23-25 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  80. Published

    Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake

    Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Et æble om dagen

    Larsen, P. J., Holst, Jens Juul & Astrup, A., 2003, In: Politiken. 29, 2 p.

    Research output: Contribution to journalContribution to newspaper - Feature articleCommunication

  82. Published

    Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea

    Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  83. Published

    The use of glycaemic index tables to predict glycaemic index of breakfast meals

    Flint, A., Møller, B. K., Raben, Anne, Tetens, Inge , Holst, Jens Juul & Astrup, A., 2005, In: British Journal of Nutrition. 94, 1, p. 135-136 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  84. Published

    Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals

    Rohrer, S., Menge, B. A., Grüber, L., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 5, p. E791-E795

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

    Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

    Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.

    Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

    Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.

    Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

    Ugleholdt, Randi Kjærsgaard, Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In: Endocrinology. 145, 3, p. 1349-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.

    Frid, A. H., Nilsson, M., Holst, Jens Juul & Björck, I. M. E., 2005, In: American Journal of Clinical Nutrition. 82, 1, p. 69-75 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.

    Ørskov, Cathrine, Hartmann, B., Poulsen, Steen Seier, Thulesen, J., Hare, K. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 124, 1-3, p. 105-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.

    Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.

    Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Somatostatin receptors.

    Møller, L. N., Stidsen, C. E., Hartmann, B. & Holst, Jens Juul, 2003, In: BBA General Subjects. 1616, 1, p. 1-84 83 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.

    Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Determinants of glycemic charges in normoglycemic individuals

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, T., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetes. Suppl. 1, p. A659-A659 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  99. Published

    Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

    Müssig, K., Staiger, H., Machicao, F., Machann, J., Schick, F., Schäfer, S. A., Claussen, C. D., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A. & Häring, H., 2009, In: Metabolism - Clinical and Experimental. 58, 12, p. 1809-11 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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