Holger Grohganz

Holger Grohganz

Associate Professor

ORCID: 0000-0002-0482-1397

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  1. Adsorption of the decapeptide Cetrorelix depends both on the composition of dissolution medium and the type of solid surface

    Grohganz, Holger, Rischer, M. & Brandl, M., 2004, In: European Journal of Pharmaceutical Sciences. 21, 2-3, p. 191-196

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Development and in vitro evaluation of a liposome based implant formulation for the decapeptide cetrorelix

    Grohganz, Holger, Tho, I. & Brandl, M., 2005, In: European Journal of Pharmaceutics and Biopharmaceutics. 59, 3, p. 439-448

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Development and validation of a HPLC method for routine quantification of the decapeptide Cetrorelix in liposome dispersions

    Grohganz, Holger, Schläfli, O., Rischer, M. & Brandl, M., 2004, In: Journal of Pharmaceutical and Biomedical Analysis. 34, 5, p. 963-969

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Quantification of various phosphatidylcholines in liposomes by enzymatic assay

    Grohganz, Holger, Ziroli, V., Massing, U. & Brandl, M., 2003, In: AAPS PharmSciTech. 4, 4

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

    Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A co-amorphous form of a substance and a protein

    Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1

    Research output: Patent

  7. Published

    A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Strachan, C. J., Rades, Thomas & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability

    Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

    Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions

    Löbmann, Korbinian, Laitinen, R., Strachan, C., Rades, Thomas & Grohganz, Holger, 1 Jan 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ

    Doreth, M., Hussein, M. A., Priemel, P. A., Grohganz, Holger, Holm, R., Lopez de Diego, H., Rades, Thomas & Löbmann, Korbinian, 15 Mar 2017, In: International Journal of Pharmaceutics. 519, 1-2, p. 343-351 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, Thomas, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.

    Research output: Contribution to journal › Review › Research

  13. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Tarp Jensen, K., Graeser, K., Strachan, C. & Rades, Thomas, 2013, In: Journal of Drug Delivery Science and Technology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

    Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying

    Craye, G., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., 2015, In: Molecules. 20, 12, p. 21532-48 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Classification of lyophilised mixtures using multivariate analysis of NIR spectra

    Grohganz, Holger, Fonteyne, M., Skibsted, E., Falck, T., Palmqvist, B. & Rantanen, Jukka, 2010, In: European Journal of Pharmaceutics and Biopharmaceutics. 74, p. 406-412

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies

    Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.

    Research output: Contribution to journal › Review › Research

  20. Published

    Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

    Löbmann, Korbinian, Strachan, C., Grohganz, Holger, Rades, Thomas, Korhonen, O. & Laitinen, R., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

    Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.

    Research output: Contribution to journal › Journal article › Research › peer-review

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