Holger Grohganz
Associate Professor
Solid State Pharmaceutics
Universitetsparken 2, 2100 København Ø
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
- Published
Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin-arginine
Lenz, E., Jensen, K. B. T., Blaabjerg, L. I., Knop, K., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Kleinebudde, P., Oct 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 96, p. 44–52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dipeptides as co-formers in co-amorphous systems
Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients
Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230Research output: Contribution to journal › Review › Research
Development and validation of a HPLC method for routine quantification of the decapeptide Cetrorelix in liposome dispersions
Grohganz, Holger, Schläfli, O., Rischer, M. & Brandl, M., 2004, In: Journal of Pharmaceutical and Biomedical Analysis. 34, 5, p. 963-969Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy
Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 2012, In: A A P S PharmSciTech. 13, 3, p. 747-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design space approach in the optimization of the spray-drying process
Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1Research output: Contribution to journal › Journal article › Research › peer-review
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Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
Löbmann, Korbinian, Strachan, C., Grohganz, Holger, Rades, Thomas, Korhonen, O. & Laitinen, R., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy
Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 21 Feb 2013, In: A A P S PharmSciTech. 14, 2, p. 901 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 2015, In: Molecules. 20, 10, p. 19571-87 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage
Sovago, I., Wang, W., Qiu, D., Raijada, D. K., Rantanen, Jukka, Grohganz, Holger, Rades, Thomas, Bond, A. D. & Löbmann, Korbinian, 2016, In: Molecules. 21, 4, p. 1-13 13 p., 509.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictive identification of co-formers in co-amorphous systems
Chambers, L. I., Grohganz, Holger, Palmelund, H., Löbmann, Korbinian, Rades, Thomas, Musa, O. M. & Steed, J. W., 2021, In: European Journal of Pharmaceutical Sciences. 157, 9 p., 105636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations
Kissi, E. O., Kasten, G., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 4247–4256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organic acids as co-formers for co-amorphous systems - Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems
Wu, W., Ueda, H., Lobmann, K., Rades, Thomas & Grohganz, Holger, Oct 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 131, p. 25-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems
Wu, W., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 15 Jan 2018, In: International Journal of Pharmaceutics. 535, 1-2, p. 86-94Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A co-amorphous form of a substance and a protein
Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1Research output: Patent
- Published
Influence of Water on Amorphous Lidocaine
Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of water and trehalose on α- and β-relaxation of freeze-dried lysozyme formulations
Vallaster, B., Engelsing, F. & Grohganz, Holger, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 194, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing the allyl-terminated copolymer methoxy(poly(ethylene glycol))-block-poly(jasmine lactone) in the development of amorphous solid dispersions: A comparative study of functionalized and non-functionalized polymer
Di, Rong, Bansal, K. K., Rosenholm, J. M., Grohganz, Holger & Rades, Thomas, 2024, In: International Journal of Pharmaceutics. 657, 12 p., 124175.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase
Larsen, B. S., Skytte, J., Svagan, A. J., Meng-Lund, H., Grohganz, Holger & Löbmann, Korbinian, 2019, In: Pharmaceutical Development and Technology. 24, 3, p. 323-328Research output: Contribution to journal › Journal article › Research › peer-review
Adsorption of the decapeptide Cetrorelix depends both on the composition of dissolution medium and the type of solid surface
Grohganz, Holger, Rischer, M. & Brandl, M., 2004, In: European Journal of Pharmaceutical Sciences. 21, 2-3, p. 191-196Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classification of lyophilised mixtures using multivariate analysis of NIR spectra
Grohganz, Holger, Fonteyne, M., Skibsted, E., Falck, T., Palmqvist, B. & Rantanen, Jukka, 2010, In: European Journal of Pharmaceutics and Biopharmaceutics. 74, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ
Doreth, M., Hussein, M. A., Priemel, P. A., Grohganz, Holger, Holm, R., Lopez de Diego, H., Rades, Thomas & Löbmann, Korbinian, 15 Mar 2017, In: International Journal of Pharmaceutics. 519, 1-2, p. 343-351 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of variation in molar ratio on co-amorphous drug-amino acid systems
Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media
Heikkinen, A. T., DeClerck, L., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of novel excipients for freeze-dried protein formulations
Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1421411
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
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158
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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
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