Gesche Jürgens

Gesche Jürgens

Clinical Professor

Member of:

  • Clinical Pharmacology


Publication year:
All
1 - 42 out of 42Page size: 50
  1. 2023
  2. Published

    Effekt på søvnen som virkning eller bivirkning til nonpsykotrope lægemidler

    Jürgens, Gesche, Jennum, Poul & Baandrup, Lone, 2023, In: Ugeskrift for Laeger. 185, 26, V02230097.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Onset of Action of Selected Second-Generation Antipsychotics (Pines)-A Systematic Review and Meta-Analyses

    Meyer, R., Skov, Kenneth, Dhillon, I. K., Olsson, E., Graudal, N. A., Baandrup, Lone & Jürgens, Gesche, 2023, In: Biomedicines. 11, 1, 82.

    Research output: Contribution to journal › Review › Research › peer-review

  4. 2022
  5. Published

    Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?

    Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    CYP2D6 Genetic Variation and Antipsychotic-Induced Weight Gain: A Systematic Review and Meta-Analysis

    Wannasuphoprasit, Y., Andersen, Stig Ejdrup, Arranz, M. J., Catalan, R., Jürgens, Gesche, Kloosterboer, S. M., Rasmussen, H. B., Bhat, A., Irizar, H., Koller, D., Polimanti, R., Wang, B., Zartaloudi, E., Austin-Zimmerman, I. & Bramon, E., 3 Feb 2022, In: Frontiers in Psychology. 12, 15 p., 768748.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Eliciting drug safety signals from patient records: a language-agnostic approach

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodriguez, C., Thorsen-Meyer, H., Gentile, S., Nielsen, A., Brunak, Søren, Jürgens, Gesche & Andersen, S., 2022, p. S15-S16. 2 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  8. Published

    Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodríguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, In: Basic & clinical pharmacology & toxicology. 131, 4, p. 282-293 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodrìguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, Authorea, (Authorea Preprints).

    Research output: Working paper › Preprint › Research

  10. 2021
  11. Published

    CYP2D6 Genotyping and Antipsychotic-Associated Extrapyramidal Adverse Effects in a Randomized Trial of Aripiprazole Versus Quetiapine Extended Release in Children and Adolescents, Aged 12-17 Years, With First Episode Psychosis

    Rudå, Ditte, mfw347, mfw347, Decara, M. S., Klauber, D. G., Fagerlund, Birgitte, Møllegaard, J. R., Linnet, Kristian, Werge, Thomas, Correll, C. U., Fink-Jensen, Anders, Jürgens, Gesche & Pagsberg, Anne Katrine, 2021, In: Journal of Clinical Psychopharmacology. 41, 6, p. 667-672

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Cellular Uptake and Intracellular Phosphorylation of GS-441524: Implications for Its Effectiveness against COVID-19

    Rasmussen, H. B., Jürgens, Gesche, Thomsen, Ragnar, Taboureau, O., Zeth, K., Hansen, P. E. & Hansen, Peter Riis, 2021, In: Viruses. 13, 7, 11 p., 1369.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Influence of sodium intake and change in sodium intake on plasma-renin in man

    Graudal, N., Hubeck-Graudal, T. & Jürgens, Gesche, 2021, In: EClinicalMedicine. 33, 100750.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis

    Skov, Kenneth, Graudal, N. A. & Jürgens, Gesche, 2021, In: Basic and Clinical Pharmacology and Toxicology. 128, 4, p. 568-578 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    The utility of pharmacogenetics testing in psychiatric populations

    Jürgens, Gesche, 2021, In: Journal of Personalized Medicine. 11, 12, 1262.

    Research output: Contribution to journal › Editorial › Research › peer-review

  16. Published

    Variation of drugs involved in acute drug toxicity presentations based on age and sex: an epidemiological approach based on European emergency departments

    Miró, Ò., Waring, W. S., Dargan, P. I., Wood, D. M., Dines, A. M., Yates, C., Giraudon, I., Moughty, A., O'Connor, N., Heyerdahl, F., Hovda, K. E., Vallersnes, O. M., Paasma, R., Pold, K., Jürgens, G., Megarbane, B., Anand, J. S., Liakoni, E., Liechti, M., Eyer, F. & 6 others, Zacharov, S., Caganova, B., Bonnici, J., Radenkova-Saeva, J., Galicia, M. & on behalf of the Euro-DEN Plus Research Group, O. B. O. T. E. P. R. G., 2021, In: Clinical Toxicology. 59, 10, p. 896-904 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2020
  18. Published

    Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia: A Randomized Clinical Trial

    Jürgens, Gesche, Andersen, Stig Ejdrup, Rasmussen, H. B., Werge, Thomas, Jensen, H. D., Kaas-Hansen, Benjamin Skov & Nordentoft, Merete, 1 Dec 2020, In: JAMA Network Open. 3, 12, p. e2027909

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Onset of antipsychotic action of selected second-generation antipsychotics - A systematic review and meta-analyses

    Meyer, R., Jürgens, Gesche & Skov, Kenneth, 1 Nov 2020, In: European Neuropsychopharmacology. 40, Suppliment 1, p. S264 1 p., P.466 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    Pulmonary administration of remdesivir in the treatment of COVID-19

    Rasmussen, H. B., Hansen, Peter Riis, Taboureau, O., Thomsen, Ragnar & Jürgens, Gesche, 2020, In: The AAPS Journal. 22, 6, p. 121

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  21. 2019
  22. Published

    The impact of human CES1 genetic variation on enzyme activity assessed by ritalinic acid/methylphenidate ratios

    Stage, C., Dalhoff, Kim, Rasmussen, H. B., Schow Guski, L., Thomsen, Ragnar, Bjerre, D., Ferrero-Miliani, L., Busk Madsen, M. & Jürgens, Gesche, 1 Jul 2019, In: Basic & Clinical Pharmacology & Toxicology. 125, 1, p. 54-61

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Different Original and Biosimilar TNF Inhibitors Similarly Reduce Joint Destruction in Rheumatoid Arthritis-A Network Meta-Analysis of 36 Randomized Controlled Trials

    Graudal, N., Kaas-Hansen, Benjamin Skov, Guski, L., Hubeck-Graudal, T., Welton, N. J. & Jürgens, Gesche, 2019, In: International Journal of Molecular Sciences. 20, 18, 19 p., 4350.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Dose-response relation between dietary sodium and blood pressure: a meta-regression analysis of 133 randomized controlled trials

    Graudal, N., Hubeck-Graudal, T., Jürgens, Gesche & Taylor, R. S., 2019, In: American Journal of Clinical Nutrition. 109, 5, p. 1273-1278

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Poor Identification of Emergency Department Acute Recreational Drug Toxicity Presentations Using Routine Hospital Coding Systems: the Experience in Denmark, Switzerland and the UK

    Wood, D. M., De La Rue, L., Hosin, A. A., Jürgens, Gesche, Liakoni, E., Heyerdahl, F., Hovda, K. E., Dines, A., Giraudon, I., Liechti, M. E. & Dargan, P. I., 2019, In: Journal of Medical Toxicology. 15, 2, p. 112-120

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2018
  27. Published

    Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate

    Kaddurah-Daouk, R., Hankemeier, T., Scholl, E. H., Baillie, R., Harms, A., Stage, C., Dalhoff, Kim, Jürgens, Gesche, Taboureau, O., Nzabonimpa, G. S., Motsinger-Reif, A. A., Thomsen, Ragnar, Linnet, Kristian, Rasmussen, H. B., INDICES Consortium, I. C. & Pharmacometabolomics Research Network, P. R. N., 1 Aug 2018, In: CPT: Pharmacometrics and Systems Pharmacology. 7, 8, p. 525-533 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Comparación de las urgencias atendidas por drogas de abuso en dos servicios de urgencias españoles con las atendidas en tres áreas europeas distintas

    Miró, Ò., Yates, C., M Dines, A., M Wood, D., I Dargan, P., Galán, I., Jerez, A., Puiguriguer, J., Stephen Waring, W., Moughty, A., O'Connor, N., Heyerdahl, F., E Hovda, K., M Vallersnes, O., Paasma, R., Põld, K., Jürgens, G., Megarbane, B., S Anand, J., Liakoni, E. & 6 others, Liechti, M., Eyer, F., Zacharov, S., Caganova, B., Giraudon, I. & Galicia, M., 2018, In: Emergencias. 30, 6, p. 384-394

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Conflicting Evidence on Health Effects Associated with Salt Reduction Calls for a Redesign of the Salt Dietary Guidelines

    Graudal, N. & Jürgens, Gesche, 2018, In: Progress in Cardiovascular Diseases. 61, 1, p. 20-26

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Sodium Excretion in Population Subgroups

    Jürgens, Gesche, 2018, In: J A M A: The Journal of the American Medical Association. 320, 7, p. 719-720

    Research output: Contribution to journal › Comment/debate › Research

  31. 2017
  32. Published

    The Pharmacokinetics of Enalapril in Relation to CES1 Genotype in Healthy Danish Volunteers

    Stage, C., Jürgens, Gesche, Guski, L. S., Thomsen, Ragnar, Bjerre, D., Ferrero-Miliani, L., Lyauk, Y. K., Berg Rasmussen, H., Dalhoff, Kim & INDICES Consortium, I. C., 6 Dec 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 6, p. 487–492

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The prognosis following amphetamine poisoning

    Horwitz, H., Dalhoff, Kim, Klemp, Marc Patrick Brag, Horwitz, A., Andersen, Jon Thor Trærup & Jürgens, Gesche, Dec 2017, In: Scandinavian Journal of Public Health. 45, 8, p. 773-781 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Reappraisal of the genetic diversity and pharmacogenetic assessment of CES1

    Ferrero-Miliani, L., Bjerre, D., Stage, C., Madsen, M. B., Jürgens, Gesche, Dalhoff, Kim & Rasmussen, H. B., Aug 2017, In: Pharmacogenomics. 18, 13, p. 1241-1257 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects

    Stage, C., Jürgens, Gesche, Guski, L. S., Thomsen, Ragnar, Bjerre, D., Ferrero-Miliani, L., Lyauk, Y. K., Berg Rasmussen, H., Dalhoff, Kim & INDICES Consortium, I. C., Jul 2017, In: British Journal of Clinical Pharmacology. 83, 7, p. 1506–1514

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Nomenclature for alleles of the human carboxylesterase 1 gene

    INDICES Consortium, I. C., 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  37. Published

    Association of Carboxylesterase 1 Gene (CES1) Polymorphism with Weight loss in Children with Attention Deficit Hyperactivity Disorder during Methylphenidate Treatment

    Oxenbøll , M., Kaalund-Jørgensen, K., Rasmussen, S., Bjerre, D., Jürgens, Gesche, Hansen, E. H., Plessen, K. J., Rasmussen, H. B. & Pagsberg, Anne Katrine, 2017, In: SM Journal of bioinformatics and Proteomics. 2, 1, 8 p., 1010.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride

    Graudal, N. A., Hubeck-Graudal, T. & Jürgens, Gesche, 2017, In: Cochrane Database of Systematic Reviews. 2017, 4, 309 p., CD004022.

    Research output: Contribution to journal › Review › Research › peer-review

  39. 2016
  40. Published

    Clinical Pharmacology in Denmark in 2016: 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality

    Brøsen, K., Andersen, Stig Ejdrup, Borregaard, J., Christensen, H. R., Christensen, P. M., Dalhoff, Kim, Damkier, P., Hallas, J., Heisterberg, J., Jessen, N., Jürgens, Gesche, Kampmann, J. P. K., Laursen, B. E., Laursen, T., Nielsen, L. P., Poulsen, B. K., Poulsen, Henrik Enghusen, Andersen, L. V., Senderovitz, T. & Sonne, J., Dec 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 6, p. 523–532 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants

    Lyauk, Y. K., Stage, C., Bergmann, T. K., Ferrero, L., Bjerre, D., Thomsen, Ragnar, Dalhoff, Kim, Rasmussen, H. B. & Jürgens, Gesche, Dec 2016, In: Clinical and Translational Science. 9, 6, p. 337–345

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Reply to Pajoumand A, Hassanian-Moghaddam H, Zamani N's Letter to the Editor Regarding Our Article ‘Adverse Events Associated with Flumazenil Treatment for the Management of Suspected Benzodiazepine Intoxication – A Systematic Review with Meta-Analyses of Randomised Trials’

    Penninga, E., Graudal, N., Ladekarl, M. B. & Jürgens, Gesche, May 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 5, p. 325-6 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  43. Published

    Adverse Events Associated with Flumazenil Treatment for the Management of Suspected Benzodiazepine Intoxication--A Systematic Review with Meta-Analyses of Randomised Trials

    Penninga, E. I., Graudal, N., Ladekarl, M. B. & Jürgens, Gesche, Jan 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 1, p. 37-44 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Reduced Dietary Sodium Intake Increases Heart Rate: A Meta-Analysis of 63 Randomized Controlled Trials Including 72 Study Populations

    Graudal, N. A., Hubeck-Graudal, T. & Jürgens, Gesche, 2016, In: Frontiers in Physiology. 7, 8 p., 111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2015
  46. Published

    Combination Therapy With and Without Tumor Necrosis Factor Inhibitors in Rheumatoid Arthritis: A Meta-Analysis of Randomized Trials

    Graudal, N., Hubeck-Graudal, T., Faurschou, M., Baslund, B. & Jürgens, Gesche, Nov 2015, In: Arthritis Care & Research. 67, 11, p. 1487-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Levothyroxine Poisoning - Symptoms and Clinical Outcome

    Nygaard, B., Saedder, E. A., Dalhoff, Kim, Wikkelsoe, M. & Jürgens, Gesche, Oct 2015, In: Basic & Clinical Pharmacology & Toxicology. 117, 4, p. 280-285

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Pregabalin kan medføre afhængighed og abstinenssymptomer

    Nordgaard, Julie & Jürgens, Gesche, 2015, In: Ugeskrift for Laeger. 177, 2A, p. 38-9 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2014
  50. Published

    Compared With Usual Sodium Intake, Low- and Excessive-Sodium Diets Are Associated With Increased Mortality: A Meta-Analysis

    Graudal, N., Jürgens, Gesche, Baslund, B. & Alderman, M. H., Sep 2014, In: American Journal of Hypertension. 27, 9, p. 1129-1137 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. 2013
  52. Published

    Neuropeptide Y genes and suicidal behaviour among schizophrenic patients

    Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2002
  54. Published

    Effect of growth hormone on hepatic cytochrome P450 activity in healthy elderly men

    Jürgens, Gesche, Lange, Kai, Reuther, Lene Ørskov, Rasmussen, B. B., Brøsen, K. & Christensen, H. R., Mar 2002, In: Clinical Pharmacology and Therapeutics. 71, 3, p. 162-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 105654998