Niels H. Secher

Niels H. Secher

Professor emeritus

Member of:

  • Anaesthesiology


  1. 2014
  2. Published

    Hydroxyethyl Starch Reduces Coagulation Competence and Increases Blood Loss During Major Surgery: Results From a Randomized Controlled Trial

    Rasmussen, K. C., Johansson, P. I., Højskov, M., Kridina, I., Kistorp, T., Thind, P., Nielsen, H. B., Ruhnau, B., Pedersen, T. & Secher, Niels H., Feb 2014, In: Annals of Surgery. 259, 2, p. 249-254 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Maximal heart rate does not limit cardiovascular capacity in healthy humans: insight from right atrial pacing during maximal exercise

    Munch, G. D. W., Svendsen, Jesper Hastrup, Damsgaard, R., Secher, Niels H., González-Alonso, J. & Mortensen, S. P., 15 Jan 2014, In: The Journal of Physiology. 592, Pt 2, p. 377-390 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Ischemic Preconditioning of One Forearm Enhances Static and Dynamic Apnea

    Kjeld, T., Rasmussen, M. R., Jattu, T., Nielsen, H. B. & Secher, Niels H., Jan 2014, In: Medicine and Science in Sports and Exercise. 46, 1, p. 151-155 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Beneficial effects of elevating cardiac preload on left-ventricular diastolic function and volume during heat stress: implications toward tolerance during a hemorrhagic insult

    Brothers, R. M., Pecini, R., Dalsgaard, M., Bundgaard-Nielsen, M., Wilson, T. E., Secher, Niels H. & Crandall, C. G., 2014, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 307, 8, p. R1036-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Case report: (Pre)syncopal symptoms associated with a negative internal jugular venous pressure

    Olesen, N. D., van Lieshout, J. J., Fisher, J. P., Seifert, T., Nielsen, H. B. & Secher, Niels H., 2014, In: Frontiers in Physiology. 5, p. 1-5 5 p., 317.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cerebral oxygenation in health and disease

    Brassard, P., Ainslie, P. N. & Secher, Niels H., 2014, In: Frontiers in Physiology. 5, p. 1-2 458.

    Research output: Contribution to journalEditorialResearchpeer-review

  8. Published

    Detailed statistical analysis plan for the pulmonary protection trial

    Buggeskov, K. B., Jakobsen, J. C., Secher, Niels H., Jonassen, Thomas, Andersen, L. W., Steinbrüchel, D. A. & Wetterslev, J., 2014, In: Trials. 15, p. 1-7 7 p., 510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Glucocorticoids improve high-intensity exercise performance in humans

    Casuso, R. A., Melskens, L., Bruhn, T., Secher, Niels H. & Nordsborg, Nikolai Baastrup, 2014, In: Journal of Applied Physiology. 114, 2, p. 419-424 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glycopyrrolate does not influence the visual or motor-induced increase in regional cerebral perfusion

    Rokamp, K. Z., Olesen, N. D., Larsson, Henrik Bo Wiberg, Hansen, Adam Espe, Seifert, T., Nielsen, H. B., Secher, Niels H. & Rostrup, E., 2014, In: Frontiers in Physiology. 5, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Influence of intranasal and carotid cooling on cerebral temperature balance and oxygenation

    Nybo, Lars, Wanscher, M. & Secher, Niels H., 2014, In: Frontiers in Physiology. 5, 5 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Inhale your blood volume!

    Secher, Niels H., 2014, In: Experimental Physiology. 99, 10, p. 1285 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Mesenterielt traktionssyndrom

    Krohn, P. S., Ambrus, R., Zaar, M., Secher, Niels H. & Svendsen, Lars Bo, 2014, In: Ugeskrift for Laeger. 176, p. 2-5 4 p., V09130546.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    O2 supplementation to secure the near-infrared spectroscopy determined brain and muscle oxygenation in vascular surgical patients: a presentation of 100 cases

    Rokamp, K. Z., Secher, Niels H., Eiberg, Jonas Peter, Lönn, Lars & Nielsen, H. B., 2014, In: Frontiers in Physiology. 5, p. 66

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Preserved frontal lobe oxygenation following calcium chloride for treatment of anesthesia-induced hypotension

    Kitchen, C., Nissen, P., Secher, Niels H. & Nielsen, H. B., 2014, In: Frontiers in Physiology. 5, p. 1-5 5 p., 407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2013
  17. Published

    A note on arterial to venous oxygen saturation as reference for NIRS-determined frontal lobe oxygen saturation in healthy humans

    Sørensen, H., Secher, Niels H. & Rasmussen, P., 2013, In: Frontiers in Physiology. 4, p. 1-3 3 p., 403.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Acute volume expansion attenuates hyperthermia-induced reductions in cerebral perfusion during simulated hemorrhage

    Schlader, Z. J., Seifert, T., Wilson, T. E., Bundgaard-Nielsen, M., Secher, Niels H. & Crandall, C. G., 2013, In: Journal of Applied Physiology. 114, 12, p. 1730-1735 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cerebral perfusion, oxygenation and metabolism during exercise in young and elderly individuals

    Fisher, J. P., Hartwich, D., Seifert, T., Olesen, N., McNulty, C. L., Nielsen, H. M. B., van Lieshout, J. J. & Secher, Niels H., 2013, In: Journal of Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Does Goal-directed Fluid Therapy Affect Postoperative Orthostatic Intolerance? A Randomized Trial

    Bundgaard-Nielsen, M., Jans, O., Müller, R. G., Korshin, A. M., Ruhnau, B., Bie, P., Secher, Niels H. & Kehlet, Henrik, 2013, In: Anesthesiology. 119, 4, p. 813-823 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    G16R single nucleotide polymorphism but not haplotypes of the ß2-adrenergic receptor gene alters cardiac output in humans

    Rokamp, K. Z., Staalsø, J. M., Gartmann, M., Sletgaard, A., Nordsborg, Nikolai Baastrup, Secher, Niels H., Nielsen, H. B. & Olsen, N. V., 2013, In: Clinical Science. 125, 4, p. 191-198 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hypercoagulability in response to elevated body temperature and central hypovolemia

    Meyer, M., Ostrowski, Sisse Rye, Overgaard, F. A., Ganio, M. S., Secher, Niels H., Crandall, C. G. & Johansson, P. I., 2013, In: Journal of Surgical Research. 185, 2, p. 93-100 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    In reply

    Sørensen, H., Secher, Niels H., Siebenmann, C., Kohl-Bareis, M., Lundby, C. & Rasmussen, P., 2013, In: Anesthesiology. 118, 4, p. 982 1 p.

    Research output: Contribution to journalComment/debateResearch

  24. Published

    Leg oxygen uptake in the initial phase of intense exercise is slowed by a marked reduction in oxygen delivery

    Christensen, P. M., Nyberg, M. P., Mortensen, S. P., Nielsen, Jens Jung, Secher, Niels H., Damsgaard, R., Hellsten, Ylva & Bangsbo, Jens, 2013, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 305, 3, p. R313-R321 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Muscle metaboreflex and autonomic regulation of heart rate in humans

    Fisher, J. P., Adlan, A. M., Shantsila, A., Secher, J. F., Sørensen, H. & Secher, Niels H., 2013, In: The Journal of Physiology. 591, 15, p. 3777-3788 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    One size does not fit all: regional cerebral blood flow and arterial carbon dioxide tension

    Secher, Niels H., 2013, In: Experimental Physiology. 98, 3, p. 654 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Protection against high intravascular pressure in giraffe legs

    Petersen, K. K., Hørlyck, A., Østergaard, K. H., Andresen, J., Brøgger, T. H., Jensen, N. S., Telinius, N., Laher, I., Bertelsen, Mads Frost, Grøndahl, C., Smerup, M. H., Secher, Niels H., Brøndum, E. T., Hasenkam, J. M., Wang, T., Baandrup, U. & Aalkjær, Christian, 2013, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 305, 9, p. R1021-R1030 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Pulmonary perfusion with oxygenated blood or custodiol HTK solution during cardiac surgery for postoperative pulmonary function in COPD patients: a trial protocol for the randomized, clinical, parallel group, assessor and data analyst blinded Pulmonary Protection Trial

    Buggeskov, K. B., Wetterslev, J., Secher, Niels H., Andersen, L. W., Jonassen, T. E. N. & Steinbrüchel, D. A., 2013, In: Trials. 14, p. 30

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Skeletal muscle signaling and the heart rate and blood pressure response to exercise: insight from heart rate pacing during exercise with a trained and a deconditioned muscle group

    Mortensen, S. P., Svendsen, Jesper Hastrup, Ersbøll, M., Hellsten, Ylva, Secher, Niels H. & Saltin, B., 2013, In: Hypertension. 61, 5, p. 1126-1133 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    When is enough enough? Individualized goal-directed fluid therapy for surgery

    Secher, Niels H., 2013, In: Journal of Clinical Monitoring and Computing. 27, 3, p. 223-224 2 p.

    Research output: Contribution to journalJournal articleCommunication

  31. 2012
  32. Published

    Both acute and prolonged administration of EPO reduce cerebral and systemic vascular conductance in humans

    Rasmussen, P., Kim, Y., Krogh-Madsen, Rikke, Lundby, C., Olsen, N. V., Secher, Niels H. & van Lieshout, J. J., Mar 2012, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26, 3, p. 1343-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Atrial Natriuretic Peptide and Acute Changes in Central Blood Volume by Hyperthermia in Healthy Humans

    Wiis Vogelsang, T., Marving, J., G. Crandall, C., Wilson, C., C. Yoshiga, C., Secher, Niels H., Hesse, B. & Kjær, Andreas, 2012, In: The Open Neuroendocrinology Journal. 5, p. 1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Blood flow in internal carotid and vertebral arteries during orthostatic stress

    Sato, K., Fisher, J. P., Seifert, T., Overgaard, M., Secher, Niels H. & Ogoh, S., 2012, In: Experimental Physiology. 97, 12, p. 1272-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Brain and skin do not contribute to the systemic rise in erythropoietin during acute hypoxia in humans

    Rasmussen, P., Nordsborg, Nikolai Baastrup, Taudorf, S., Sørensen, H., Berg, Ronan Martin Griffin, Jacobs, R. A., Bailey, D. M., Olsen, N. V., Secher, Niels H., Møller, Kirsten & Lundby, C., 2012, In: F A S E B Journal. 26, 5, p. 1831-1834 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Colloid volume loading does not mitigate decreases in central blood volume during simulated hemorrhage while heat stressed

    Crandall, C. G., Wilson, T. E., Marving, J., Bundgaard-Nielsen, M., Seifert, T., Klausen, T., Andersen, F., Secher, Niels H. & Hesse, B., 2012, In: Journal of Physiology. p. 1287-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine

    Holm-Sørensen, H., Secher, Niels H., Siebenmann, C., Nielsen, H. M. B., Kohl-Bareis, M., Lundby, C. & Rasmussen, P., 2012, In: Anesthesiology. 117, 2, p. 263-270 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effect of heat stress on cardiac output and systemic vascular conductance during simulated hemorrhage to presyncope in young men

    Ganio, M. S., Overgaard, M., Seifert, T., Secher, Niels H., Johansson, P. I., Meyer, M. & Crandall, C. G., 2012, In: American Journal of Physiology: Heart and Circulatory Physiology. 302, 8, p. H1756-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Endotoxemia reduces cerebral perfusion but enhances dynamic cerebrovascular autoregulation at reduced arterial carbon dioxide tension*

    Brassard, P., Kim, Y., van Lieshout, J., Secher, Niels H. & Rosenmeier, J. B., 2012, In: The Open Critical Care Medicine Journal. 40, 6, p. 1873-1878 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Food for thought

    Secher, Niels H. & Rasmussen, P., 2012, In: Journal of Physiology. 590, Pt 5, p. 1013

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Human investigations into the exercise pressor reflex

    Secher, Niels H. & Amann, M., 2012, In: Experimental Physiology. 97, 1, p. 59-69 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Hypoxia and exercise provoke both lactate release and lactate oxidation by the human brain

    Overgaard, M., Rasmussen, P., Bohm, A. M., Seifert, T., Brassard, P., Zaar, M., Homann, P. H., Evans, K. A., Nielsen, H. B., Secher, Niels H. & Nielsen, H. M. B., 2012, In: F A S E B Journal. p. 3012-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    One-legged endurance training: leg blood flow and oxygen extraction during cycling exercise

    Rud, B., Foss, O., Krustrup, P., Secher, Niels H. & Hallén, J., 2012, In: Acta Physiologica (Print). 205, 1, p. 177-185 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Orthostatic leg blood volume changes assessed by near-infrared spectroscopy

    Truijen, J., Kim, Y. S., Krediet, C. T. P., Stok, W. J., Kölgen, R. S., Colier, W. N., Secher, Niels H. & van Lieshout, J. J., 2012, In: Experimental Physiology. 97, 3, p. 353-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Peripheral circulation: In Comprehensive Physiology

    Laughlin, M., Secher, Niels H., Davis, M., Van Lieshout, J., Arce-Esquivel, A., Simmons, G., Bender, S., Padilla, J., Bache, R., Merkus, D. & Duncker, D., 2012

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  46. Published

    Peripheral vasodilatation determines cardiac output in exercising humans: insight from atrial pacing

    Bada, A. A., Svendsen, Jesper Hastrup, Secher, Niels H., Saltin, B. & Mortensen, S. P., 2012, In: Journal of Physiology. 590, Pt 8, p. 2051-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Pulmonary artery and intestinal temperatures during heat stress and cooling

    Pearson, J., Ganio, M. S., Seifert, T., Overgaard, M., Secher, Niels H. & Crandall, C. G., 2012, In: Medicine and Science in Sports and Exercise. 44, 5, p. 857-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Renal lactate elimination is maintained during moderate exercise in humans

    Volianitis, S., Dawson, E. A., Dalsgaard, M., Yoshiga, C., Clemmesen, J., Secher, Niels H., Olsen, N. V. & Nielsen, H., 2012, In: Serbian Journal of Sports Sciences. 30, 2, p. 149-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The role of haemoglobin mass on VO(2)max following normobaric 'live high-train low' in endurance-trained athletes

    Robach, P., Siebenmann, C., Jacobs, R. A., Rasmussen, P., Nordsborg, Nikolai Baastrup, Pesta, D., Gnaiger, E., Díaz, V., Christ, A., Fiedler, J., Crivelli, N., Secher, Niels H., Pichon, A., Maggiorini, M. & Lundby, C., 2012, In: British Journal of Sports Medicine. 46, 11, p. 822-827 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Thigh oxygen uptake at the onset of intense exercise is not affected by a reduction in oxygen delivery caused by hypoxia

    Christensen, P. M., Nordsborg, Nikolai Baastrup, Nybo, Lars, Mortensen, S. P., Sander, M., Secher, Niels H. & Bangsbo, Jens, 2012, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 303, 8, p. R843-R849 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2011
  52. Published

    In cirrhotic patients reduced muscle strength is unrelated to muscle capacity for ATP turnover suggesting a central limitation

    Gam, C. M. B., Nielsen, H. B., Secher, Niels H., Larsen, F. S., Ott, P. & Quistorff, B., May 2011, In: Clinical Physiology and Functional Imaging. 31, 3, p. 169-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Intensive blood pressure control affects cerebral blood flow in type 2 diabetes mellitus patients

    Kim, Y., Davis, S. C. A. T., Truijen, J., Stok, W. J., Secher, Niels H. & van Lieshout, J. J., 1 Apr 2011, In: Hypertension. 57, 4, p. 738-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Interindividual variation in platelets and the cardiovascular response to haemorrhage in the pig

    Zaar, M., Secher, Niels H., Gam, C. M. B., Rasmussen, P. & Jo­hans­son, Pär In­ge­mar , 1 Mar 2011, In: Blood Coagulation and Fibrinolysis. 22, 2, p. 92-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3104085