Niels H. Secher

Niels H. Secher

Professor emeritus

Member of:

  • Anaesthesiology


  1. 2019
  2. Published

    Role of spleen and liver for enhanced hemostatic competence following administration of adrenaline to humans

    Niemann, M. J., Lund, A., Lunen, T. B., Zaar, M., Clemmesen, J. O., Plomgaard, Peter Stendahl, Nielsen, H. B. & Secher, Niels H., Apr 2019, In: Thrombosis Research. 176, p. 95-100

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Cardiac output during exercise is related to plasma atrial natriuretic peptide but not to central venous pressure in humans

    Yoshiga, C., Dawson, E. A., Volianitis, S., Warberg, J. & Secher, Niels H., Mar 2019, In: Experimental Physiology. 104, 3, p. 379-384

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Dynamic Cerebral Autoregulation Is Maintained during High-Intensity Interval Exercise

    Tsukamoto, H., Hashimoto, T., Olesen, N. D., Petersen, Lonnie Grove, Sørensen, H., Nielsen, H. B., Secher, Niels H. & Ogoh, S., Feb 2019, In: Medicine and Science in Sports and Exercise. 51, 2, p. 372-378 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Human brain blood flow and metabolism during isocapnic hyperoxia: the role of reactive oxygen species

    Mattos, J. D., Campos, M. O., Rocha, M. P., Mansur, D. E., Rocha, H. N. M., Garcia, V. P., Batista, G., Alvares, T. S., Oliveira, G. V., Souza, M. V., Videira, R. L. R., Rocha, N. G., Secher, Niels H., Nóbrega, A. C. L. & Fernandes, I. A., Feb 2019, In: Journal of Physiology. 597, 3, p. 741-755

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effect of early versus delayed activation of thoracic epidural anesthesia on plasma pro-atrial natriuretic peptide to indicate deviations in central blood volume during esophagectomy

    Strandby, R. B., Ambrus, R., Achiam, Michael Patrick, Goetze, J. P., Secher, Niels H. & Svendsen, Lars Bo, 2019, In: Regional Anesthesia and Pain Medicine. 44, 8, p. 787-792

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of hypotensive hypovolemia and thoracic epidural anesthesia on plasma pro-atrial natriuretic peptide to indicate deviations in central blood volume in pigs: a blinded, randomized controlled trial

    Strandby, R. B., Ambrus, R., Achiam, Michael Patrick, Henriksen, A., Goetze, J. P., Secher, Niels H. & Svendsen, Lars Bo, 2019, In: Local and Regional Anesthesia. 12, p. 47-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Fluid therapy for critical haemorrhage during elective noncardiac surgery

    Rasmussen, K. C., Secher, Niels H. & Pedersen, T., 2019, In: European Journal of Anaesthesiology. 36, 1, p. 77-78 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  9. Published

    Hypoxia-induced vagal withdrawal is independent of the hypoxic ventilatory response in men

    Siebenmann, C., Ryrsø, C. K., Oberholzer, L., Fisher, J. P., Hilsted, Linda, Rasmussen, P., Secher, Niels H. & Lundby, C., 2019, In: Journal of Applied Physiology. 126, 1, p. 124-131 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Nasal insulin administration does not affect hepatic glucose production at systemic fasting insulin levels

    Plomgaard, Peter Stendahl, Hansen, J. S., Ingerslev, B., Clemmesen, J. O., Secher, Niels H., van Hall, G., Fritsche, A., Weigert, C., Lehmann, R., Häring, H. U. & Heni, M., 2019, In: Diabetes, Obesity and Metabolism. 21, 4, p. 993-1000

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Protocol for a multicentre retrospective observational cohort study in Denmark: association between the intraoperative peripheral perfusion index and postoperative morbidity and mortality in acute non-cardiac surgical patients

    Agerskov, M., Thusholdt, A. N. W., Højlund, Jakob, Meyhoff, Christian Sylvest, Sørensen, H., Wiberg, S., Secher, Niels H. & Foss, Nicolai Bang, 2019, In: B M J Open. 9, 11, 6 p., e031249.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Regulation of Heart Rate and Blood Pressure During Exercise in Humans

    Fisher, J. P. & Secher, Niels H., 2019, Muscle and Exercise Physiology. Zoladz, J. A. (ed.). Elsevier, p. 541-560 20 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  13. Published

    The age-related reduction in cerebral blood flow affects vertebral artery more than internal carotid artery blood flow

    Olesen, N. D., Nielsen, H. B., Olsen, N. V. & Secher, Niels H., 2019, In: Clinical Physiology and Functional Imaging. 39, 4, p. 255-260

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Time trial performance is sensitive to low-volume autologous blood transfusion

    Bejder, Jacob, Andersen, A. B., Solheim, S. A., Gybel-Brask, M., Secher, Niels H., Johansson, P. I. & Nordsborg, Nikolai Baastrup, 2019, In: Medicine and Science in Sports and Exercise. 51, 4, p. 692-700 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2018
  16. Published

    Phenylephrine increases near-infrared spectroscopy determined muscle oxygenation during head-up tilt in men

    Egesborg, A. H., Sørensen, H., Olesen, N. D. & Secher, Niels H., 17 Nov 2018, In: Scandinavian Journal of Clinical & Laboratory Investigation. 78, 7-8, p. 601-605

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Elevated arterial lactate delays recovery of intracellular muscle pH after exercise

    Volianitis, S., Secher, Niels H. & Quistorff, B., Nov 2018, In: European Journal of Applied Physiology. 118, 11, p. 2429-2434

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Muscle alpha-adrenergic responsiveness during exercise and ATP-induced vasodilation in chronic obstructive pulmonary disease patients

    Iepsen, Ulrik Winning, Munch, G. W., Ryrso, C. K., Secher, Niels H., Lange, Peter, Thaning, P., Pedersen, Bente Klarlund & Mortensen, S. P., Feb 2018, In: American Journal of Physiology: Heart and Circulatory Physiology. 314, 2, p. H180-H187 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A mesenteric traction syndrome affects near-infrared spectroscopy evaluated cerebral oxygenation because skin blood flow increases

    Olesen, N. D., Sørensen, H., Ambrus, R., Svendsen, Lars Bo, Lund, A. & Secher, Niels H., 2018, In: Journal of Clinical Monitoring and Computing. 32, 2, p. 261-268

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Absent increase in vertebral artery blood flow during l-arginine infusion in hypertensive men

    Vianna, L. C., Fernandes, I. A., Barbosa, T. C., Amaral, T. G., Rocha, N. G., Secher, Niels H. & Nóbrega, A. C., 2018, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 315, 4, p. R820-R824 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Administration of platelets to ruptured abdominal aortic aneurysm patients before open surgery: a prospective, single-blinded, randomised study

    Lunen, T. B., Johansson, P. I., Jensen, L. P., Homburg, K. M., Roeder, O. C., Lönn, Lars, Secher, Niels H., Helgstrand, U., Carstensen, M., Jensen, K. B., Lange, Theis, Sillesen, Henrik, Swiatek, F. & Nielsen, H. B., 2018, In: Transfusion Medicine. 28, 5, p. 386-391

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Elevated Renal Oxygen Extraction During Open Abdominal Aortic Aneurysm Repair Is Related to Postoperative Renal Dysfunction

    Olesen, N. D., Jørgensen, T. B., Eiberg, Jonas Peter, Helgstrand, U. J. V., Sillesen, Henrik, Cedergreen, P., Secher, Niels H. & Nielsen, H. B., 2018, In: Seminars in Cardiothoracic and Vascular Anesthesia. 22, 4, p. 369-375

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation

    Bailey, D. M., Rasmussen, P., Evans, K. A., Bohm, A. M., Zaar, M., Nielsen, H. B., Brassard, P., Nordsborg, Nikolai Baastrup, Homann, P. H., Raven, P. B., McEneny, J., Young, I. S., McCord, J. M. & Secher, Niels H., 2018, In: Free Radical Biology & Medicine. 124, p. 104-113 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    In response to: phenylephrine and paradoxically increased muscle tissue oxygenation: is the mechanism related to local venoconstriction or augmented venous return?

    Sørensen, H., Egesborg, A. H., Thomsen, J. H., Meyer, A. S. P., Terzic, D., Hilsted, L., Kjærgaard, J., Goetze, J. P., Barbosa, T. C. & Secher, Niels H., 2018, In: Journal of Clinical Monitoring and Computing. 32, 6, p. 1145-1146

    Research output: Contribution to journalComment/debateResearch

  25. Published

    Maintained exercise-enhanced brain executive function related to cerebral lactate metabolism in men

    Hashimoto, T., Tsukamoto, H., Takenaka, S., Olesen, N. D., Petersen, Lonnie Grove, Sørensen, H., Nielsen, H. B., Secher, Niels H. & Ogoh, S., 2018, In: FASEB Journal. 32, 3, p. 1417-1427 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women

    Bertelsen, D. M., Neergaard, J. S., Bager, C. L., Nielsen, S. H., Secher, Niels H., Svendsen, Jesper Hastrup, Bihlet, A. R., Andersen, J. R., Karsdal, M. A., Christiansen, C. & Nielsen, H. B., 2018, In: Scientific Reports. 8, 7 p., 5371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Perioperativ væsketerapi har indflydelse på koagulation, blodtab og komplikationer

    Rasmussen, K. C., Pedersen, T. & Secher, Niels H., 2018, In: Ugeskrift for Laeger. 180, 21, 4 p., V06170498.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Pre-operative haemodynamic monitoring and resuscitation in hip fracture patients: Protocol for a prospective observational study

    Agerskov, M., Sørensen, H., Højlund, Jakob, Secher, Niels H. & Foss, Nicolai Bang, 2018, In: Acta Anaesthesiologica Scandinavica. 62, 9, p. 1314-1320 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Reduced arterial vasodilatation in response to hypoxia impairs cerebral and peripheral oxygen delivery in hypertensive men

    Fernandes, I. A., Rocha, M. P., Campos, M. O., Mattos, J. D., Mansur, D. E., Rocha, H. N. M., Terra, P. A. C., Garcia, V. P., Rocha, N. G., Secher, Niels H. & Nóbrega, A. C. L., 2018, In: The Journal of Physiology. 596, 7, p. 1167-1179

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Sodium nitroprusside dilates cerebral vessels and enhances internal carotid artery flow in young men

    Olesen, N. D., Fischer, Mads & Secher, Niels H., 2018, In: Journal of Physiology. 596, 17, p. 3967-3976 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2017
  32. Published

    Phenylephrine increases near-infrared spectroscopy determined muscle oxygenation in men

    Sørensen, H., Thomsen, J. H., Meyer, A. S. P., Terzic, D., Hilsted, L., Kjærgaard, J., Goetze, Jens P. , Barbosa, T. C. & Secher, Niels H., Dec 2017, In: Journal of Clinical Monitoring and Computing. 31, 6, p. 1159–1166 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP

    Ingerslev, B., Hansen, J. S., Hoffmann, C., Clemmesen, J. O., Secher, Niels H., Scheler, M., Hrabĕ de Angelis, M., Häring, H. U., Pedersen, Bente Klarlund, Weigert, C. & Plomgaard, P., Oct 2017, In: Molecular Metabolism. 6, 10, p. 1286-1295 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Effect of pulmonary hyperinflation on central blood volume: An MRI study

    Mijacika, T., Kyhl, K., Frestad, D., Otto Barak, F., Drvis, I., Secher, Niels H., Dujic, Z. & Lav Madsen, P., Sep 2017, In: Respiratory Physiology & Neurobiology. 243, p. 92-96 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Regulation of leg blood flow is impaired during exercise in COPD patients

    Iepsen, U. W., Munch, G., Rugbjerg, M., Ryrsø, C., Secher, Niels H., Hellsten, Ylva, Lange, Peter, Pedersen, Bente Klarlund, Thaning, P. & Mortensen, S., Sep 2017, In: Acta Anaesthesiologica Scandinavica. 61, 8, p. 1041-1042 2 p., 128.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  36. Published

    Severe Postoperative Complications may be Related to Mesenteric Traction Syndrome during Open Esophagectomy

    Ambrus, R., Svendsen, Lars Bo, Secher, Niels H., Goetze, Jens P. , Rünitz, K. & Achiam, Michael Patrick, Sep 2017, In: Scandinavian Journal of Surgery. 106, 3, p. 241-248 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Gly16 allele of the G16R single nucleotide polymorphism in the β2-adrenergic receptor gene augments the glycemic response to adrenaline in humans

    Rokamp, K. Z., Staalsø, J. M., Zaar, M., Rasmussen, P., Petersen, Lonnie Grove, Nielsen, R. V., Secher, Niels H., Olsen, N. V. & Nielsen, H. B., Sep 2017, In: Frontiers in Physiology. 8, SEP, 10 p., 661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Postoperative volume balance: does stroke volume increase in Trendelenburg's position?

    Frost, H., Mortensen, C. R., Secher, Niels H. & Nielsen, H. B., May 2017, In: Clinical Physiology and Functional Imaging. 37, 3, p. 314-316 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Blood pooling in extrathoracic veins after glossopharyngeal insufflation

    Mijacika, T., Frestad, D., Kyhl, K., Barak, O., Drvis, I., Secher, Niels H., Buca, A., Obad, A., Dujic, Z. & Madsen, P. L., Apr 2017, In: European Journal of Applied Physiology. 117, 4, p. 641-649 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Plasma pro-atrial natriuretic peptide to estimate fluid balance during open and robot-assisted esophagectomy: a prospective observational study

    Strandby, R. B., Ambrus, R., Secher, Niels H., Goetze, Jens P. , Achiam, Michael Patrick & Svendsen, Lars Bo, 3 Feb 2017, In: B M C Anesthesiology. 17, 7 p., 20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Nitrite and S-Nitrosohemoglobin Exchange Across the Human Cerebral and Femoral Circulation: Relationship to Basal and Exercise Blood Flow Responses to Hypoxia

    Bailey, D. M., Peter, R., Overgaard, M., Evans, K. A., Bohm, A. M., Seifert, T., Brassard, P., Zaar, M., Nielsen, H. B., Raven, P. B. & Secher, Niels H., 10 Jan 2017, In: Circulation. 135, 2, p. 166-176 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Whole body hyperthermia, but not skin hyperthermia, accelerates brain and locomotor limb circulatory strain and impairs exercise capacity in humans

    Trangmar, S. J., Chiesa, S. T., Kalsi, K. K., Secher, Niels H. & González-Alonso, J., Jan 2017, In: Physiological Reports. 5, 2, 17 p., e13108.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A reduced gastric corpus microvascular blood flow during Ivor-Lewis esophagectomy detected by laser speckle contrast imaging technique

    Ambrus, R., Svendsen, Lars Bo, Secher, Niels H., Rünitz, K., Frederiksen, H., Svendsen, M. B. S., Siemsen, M., Kofoed, S. C. & Achiam, Michael Patrick, 2017, In: Scandinavian Journal of Gastroenterology. 52, 4, p. 455-461 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    ACCURACY OF NONINVASIVE ANESTHETIC MONITORING IN THE ANESTHETIZED GIRAFFE (GIRAFFA CAMELOPARDALIS)

    Bertelsen, Mads Frost, Grondahl, C., Stegmann, G. F., Sauer, C., Secher, Niels H., Hasenkam, J. M., Damkjaer, M., Aalkjaer, C. & Wang, T., 2017, In: Journal of Zoo and Wildlife Medicine. 48, 3, p. 609-615

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Carbon monoxide reduces near-infrared spectroscopy determined 'total' hemoglobin: a human volunteer study

    Niemann, M. J., Sørensen, H., Siebenmann, C., Lundby, C. & Secher, Niels H., 2017, In: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 4, p. 259-262

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Evaluation of Gastric Microcirculation by Laser Speckle Contrast Imaging During Esophagectomy: Presented at the Annual Meeting of the Danish Surgical Society, Copenhagen, Denmark, November 2016.

    Ambrus, R., Achiam, Michael Patrick, Secher, Niels H., Svendsen, M. B. S., Rünitz, K., Siemsen, M. & Svendsen, Lars Bo, 2017, In: Journal of the American College of Surgeons. 225, 3, p. 395-402

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Leg blood flow is impaired during small muscle mass exercise in patients with COPD

    Iepsen, Ulrik Winning, Munch, G. D. W., Rugbjerg, M., Ryrsø, C. K., Secher, Niels H., Hellsten, Ylva, Lange, Peter, Pedersen, Bente Klarlund, Thaning, P. & Mortensen, S. P., 2017, In: Journal of Applied Physiology. 123, 3, p. 624-631 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Muscle oxygen saturation increases during head-up tilt-induced (pre)syncope

    Lund, A., Sorensen, H., Jensen, T. W., Niemann, M. J., Olesen, N. D., Nielsen, H. B., Olsen, N. V. & Secher, Niels H., 2017, In: Acta Physiologica. 221, 1, p. 74-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Physiological, biochemical, anthropometric, and biomechanical influences on exercise economy in humans

    Lundby, C., Montero, D., Gehrig, S., Andersson Hall, U., Kaiser, P., Boushel, R., Meinild Lundby, A., Kirk, N., Valdivieso, P., Flück, M., Secher, Niels H., Edin, F., Hein, T. & Madsen, K., 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 12, p. 1627-1637

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Thermodilution-determined Internal Jugular Venous Flow

    Rasmussen, P., Widmer, M., Hilty, M. P., Hug, M., Sørensen, H., Ogoh, S., Sato, K., Secher, Niels H., Maggiorini, M. & Lundby, C., 2017, In: Medicine and Science in Sports and Exercise. 49, 4, p. 661-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Tympanic membrane temperature decreases during head up tilt: relation to frontal lobe oxygenation and middle cerebral artery mean blood flow velocity

    Lorr, D., Lund, A., Fredrikson, M. & Secher, Niels H., 2017, In: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 8, p. 587-591

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2016
  53. Published

    ADRB2 gly16gly Genotype, Cardiac Output, and Cerebral Oxygenation in Patients Undergoing Anesthesia for Abdominal Aortic Aneurysm Surgery

    Staalso, J. M., Rokamp, K. Z., Olesen, N. D., Lönn, Lars, Secher, Niels H., Olsen, N. V., Mantoni, T., Helgstrand, U. & Nielsen, H. M. B., Dec 2016, In: Anesthesia and Analgesia. 123, 6, p. 1408-1415 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Coupling between arterial and venous cerebral blood flow during postural change

    Ogoh, S., Washio, T., Sasaki, H., Petersen, Lonnie Grove, Secher, Niels H. & Sato, K., Dec 2016, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 311, 6, p. R1255-R1261 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3104085