Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    The physiology and pharmacology of incretins in type 2 diabetes mellitus

    Holst, Jens Juul, 2008, In: Diabetes, Obesity and Metabolism. 10, Suppl. 3, p. 14-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The incretin system and its role in type 2 diabetes mellitus

    Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake

    Sørensen, L. B., Cueto, H. T., Andersen, M. T., Bitz, C., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 5, p. 1163-1169 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  8. Published

    The Relationship between Glucagon-Like Peptide 2 and Feeding Intolerance in Preterm Infants.

    Ozer, E. A., Holst, Jens Juul, Duman, N., Kumral, A. & Ozkan, H., 2008, In: Journal of Tropical Pediatrics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Temporal changes in the intestinal growth promoting effects of glucagon-like peptide 2 following intestinal resection

    Kaji, T., Tanaka, H., Redstone, H., Wallace, L. E., Holst, Jens Juul & Sigalet, D. L., 2008, In: Journal of Surgical Research. 152, 2, p. 271-80 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients

    Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., May 2008, In: Diabetes. 57, 5, p. 1340-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients

    Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., 2008, In: Diabetes. 57, 5, p. 1340-1348 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: Challenges and feasibility

    Knop, F. K., Holst, Jens Juul & Vilsbøll, Tina, 2008, In: IDrugs. The Investigational Drugs Journal. 11, 7, p. 497-501 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: challenges and feasibility

    Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, T., Jul 2008, In: I Drugs: the Investigational Drugs Journal. 11, 7, p. 497-501 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., Aug 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-937 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Progression from normal glucose tolerance to impaired fasting glycaemia and impaired glucose tolerance: differential roles of insulin resistance and beta cell dysfunction

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Pedersen, O., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetologia. 51, Suppl. 1, p. S85-S86

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance

    Vollmer, K., Holst, Jens Juul, Baher, B., Ellrichmann, M., Nauck, M. A., Schmidt, W. E. & Meier, J. J., 2008, In: Diabetes. 57, 3, p. 678-687 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Plasma glucagon-like peptide 1 and peptide YY levels are not altered in symptomatic fructose-sorbitol malabsorption.

    Valeur, J., Øines, E., Morken, M. H., Holst, Jens Juul & Berstad, A., 2008, In: Scandinavian Journal of Gastroenterology. 43, 10, p. 1212-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Overview of incretin hormones.

    Holst, Jens Juul & Lasalle, J., 2008, In: Journal of Family Practice. 57, 9, p. 53-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Overconsumption and obesity: Peptides and susceptibility to weight gain

    Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 2008, In: Regulatory Peptides. 149, 1-3, p. 32-38 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Overconsumption and obesity: peptides and susceptibility to weight gain

    Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafsson, T., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 7 Aug 2008, In: Regulatory Peptides. 149, 1-3, p. 32-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K. H., Schmidt, W. E., Schmitz, F. & Meier, J. J., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3995-3998 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K., Schmidt, W. E., Schmitz, F. & Meier, J. J., Oct 2008, In: The Journal of clinical endocrinology and metabolism. 93, 10, p. 3995-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects

    Enç, F. Y., Ones, T., Akin, H. L., Dede, F., Turoglu, H. T., Ulfer, G., Bekiroglu, N., Haklar, G., Rehfeld, Jens Frederik, Holst, Jens Juul, Ulusoy, N. B. & Imeryüz, N., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 296, 3, p. G482-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects

    Greenfield, J. R., Farooqi, I. S., Keogh, J. M., Henning, E., Habib, A. M., Blackwood, A., Reimann, F., Holst, Jens Juul & Gribble, F. M., 2008, In: American Journal of Clinical Nutrition. 89, 1, p. 106-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects

    Lerche, S., Soendergaard, L., Rungby, J., Moeller, N., Holst, Jens Juul, Schmitz, O. E. & Brock, B., 2008, In: Clinical Endocrinology. 71, 4, p. 500-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, Torben, Jørgensen, T. & Borch-Johnsen, K., 2008, In: Diabetes Care. 32, 3, p. 439-44 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.

    Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Meal-induced compositional changes in blood and saliva in persons with bulimia nervosa

    Dynesen, A. W., Jensen, A. B., Astrup, A., Petersson, B., Holst, Jens Juul & Nauntofte, B., 2008, In: American Journal of Clinical Nutrition. 87, 1, p. 12-22 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-1071 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., Jul 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-71 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats

    Nelson, D. W., Murali, S. G., Liu, X., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., Apr 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats

    Nelson, D. W., Murali, S. G., Liu, X. W., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-R1184

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study

    Laakso, M., Zilinskaite, J., Hansen, Torben, Boesgaard, T. W., Vänttinen, M., Stancáková, A., Jansson, P., Pellmé, F., Kuulasmaa, T., Hribal, M. L., Sesti, G., Stefan, N., Fritsche, A., Häring, H., Pedersen, Oluf Borbye, Smith, U., EUGENE2 Consortium, E. C. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 3, p. 502-11 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast

    Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Björck, I. M. E., Apr 2008, In: Journal of Nutrition. 138, 4, p. 732-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast

    Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Bjorck, I. M., 2008, In: Journal of Nutrition. 138, 4, p. 732-739 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis

    Kalaitzakis, E., Sadik, R., Holst, Jens Juul, Ohman, L. & Björnsson, E., 2008, In: Clinical Gastroenterology and Hepatology. 7, 3, p. 346-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor

    Murphy, R., Tura, A., Clark, P. M., Holst, Jens Juul, Mari, A. & Hattersley, A. T., 2008, In: Diabetologia. 52, 1, p. 154-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Glucagon-like peptide-2 increases mesenteric blood flow in humans

    Bremholm, L., Hornum, Mads, Henriksen, B. M., Larsen, S. & Holst, Jens Juul, 2008, In: Scandinavian Journal of Gastroenterology. 44, 3, p. 314-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Glucagon-like peptide-1, glucose homeostasis and diabetes.

    Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

    de, H. J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 12, p. 2263-2270 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

    de Heer, J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, Dec 2008, In: Diabetologia. 51, 12, p. 2263-70 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Glucagon-like peptide-1 inhibits blood-brain glucose transfer in humans

    Lerche, S., Brock, B., Rungby, J., Bøtker, H. E., Møller, N., Rodell, A., Bibby, B. M., Holst, Jens Juul, Schmitz, O. & Gjedde, Albert, 2008, In: Diabetes. 57, 2, p. 325-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, E. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, Jens Juul, Fuller, P. J. & Bines, J. E., Jan 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, T. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, J. J., Fuller, P. J., Bines, J. E. & Holst, Jens Juul, 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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