Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression

    Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice

    Waget, A., Cabou, C., Masseboeuf, M., Cattan, P., Armanet, M., Karaca, M., Castel, J., Garret, C., Payros, G., Maida, A., Sulpice, T., Holst, Jens Juul, Drucker, D. J., Magnan, C. & Burcelin, R., Aug 2011, In: Endocrinology. 152, 8, p. 3018-3029 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men

    Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., Jun 2006, In: Journal of Nutrition. 136, 6, p. 1511-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men

    Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., 2006, In: Journal of Nutrition. 136, 6, p. 1511-1516 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

    Vrieze, A., Out, C., Fuentes, S., Jonker, L., Reuling, I., Kootte, R. S., van Nood, E., Holleman, F., Knaapen, M., Romijn, J. A., Soeters, M. R., Blaak, E. E., Dallinga-Thie, G. M., Reijnders, D., Ackermans, M. T., Serlie, M. J., Knop, F. K., Holst, J. J., van der Ley, C., Kema, I. P. & 6 others, Zoetendal, E. G., de Vos, W. M., Hoekstra, J. B. L., Stroes, E. S., Groen, A. K. & Nieuwdorp, M., Apr 2014, In: Journal of Hepatology. 60, 4, p. 824-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans

    Vollmer, K., Gardiwal, H., Menge, B. A., Goetze, O., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1379-85 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance

    Vollmer, K., Holst, Jens Juul, Baher, B., Ellrichmann, M., Nauck, M. A., Schmidt, W. E. & Meier, J. J., 2008, In: Diabetes. 57, 3, p. 678-687 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test

    Voldstedlund, Christian T, Sjøberg, K. A., Schlabs, Farina Leonie, Sigvardsen, Casper Møller, Andersen, Nicoline Resen, Holst, Jens Juul, Hartmann, Bolette, Wojtaszewski, Jørgen F P, Kiens, Bente, McConell, G. K. & Richter, Erik A., 2024, In: Diabetologia. 67, p. 1386–1398

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery

    Visentin, R., Brodersen, K., Richelsen, B., Møller, N., Dalla Man, C., Pedersen, A. K., Abrahamsen, J., Holst, Jens Juul & Nielsen, M. F., 2023, In: Journal of Diabetes Research. 2023, 14 p., 127426.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Evaluation of ß-cell secretory capacity using glucagon-like peptide-1

    Visbøll, T., Toft-Nielsen, M., Krarup, T., Madsbad, S., Dinesen, B. & Holst, Jens Juul, 2000, In: Diabetes Care. 23, p. 807-812

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Incretin hormones and diabetes mellitus

    Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  13. Published

    No reactive hypoglycaemia in type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose

    Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, Jens Juul, 1 Feb 2001, In: Diabetic Medicine. 18, 2, p. 144-149 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The spectrum of antidiabetic actions of GLP-1 in patients with diabetes

    Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

    Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Inkretiner

    Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  17. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and in people with type 1 and type 2 diabetes mellitus

    Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, S., Vølund, A., Juul, A. G. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2706-2713

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype

    Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Similar elimination rates of GLP-1 in obese type 2 diabetic patients and matched healthy subjects

    Vilsbøll, T., Krarup, T., Agersø, H. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 220-224

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Incretins, insulin secretion and Type 2 diabetes mellitus

    Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects

    Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus

    Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Incretins, insulin secretion and type 2 diabetes mellitus

    Vilsboll, T. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 654-662

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Increased glucose-stimulated FGF21 response to oral glucose in obese non-diabetic subjects after Roux-en-Y Gastric Bypass

    Vienberg, S. G., Jacobsen, S. H., Worm, D., Hvolris, L. E., Naver, L. P. S., Almdal, Thomas Peter, Hansen, D. L., Wulff, B. S., Clausen, T. R., Madsbad, Sten, Holst, Jens Juul & Andersen, B., Jan 2017, In: Clinical Endocrinology. 86, 1, p. 156-159 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

    Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, Hulot, J., Lewinter, C., Pedersen, H. K., Quinquis, B., Rouault, C., Roume, H., Salem, J., Søndertoft, N. B., Touch, S., Dumas, M., Ehrlich, S. D., Galan, P., Gøtze, J. P., Hansen, Torben, Holst, Jens Juul, Køber, Lars Valeur, Letunic, I., Nielsen, J., Oppert, J., Stumvoll, M., Vestergaard, H., Zucker, J., Bork, P., Pedersen, Oluf Borbye, Bäckhed, F., Clément, K., Raes, J. & MetaCardis Consortium, M. C., 2020, In: Nature. 581, 7808, p. 310-315

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets

    Vidarsdottir, S., Roelfsema, F., Streefland, T., Holst, Jens Juul, Rehfeld, Jens Frederik & Pijl, H., 2009, In: European Journal of Endocrinology. 162, 1, p. 75-83 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Acute effects of ghrelin administration on glucose and lipid metabolism.

    Vestergaard, E. T., Djurhuus, C. B., Gjedsted, J., Nielsen, S., Møller, N., Holst, Jens Juul, Jørgensen, J. O. L. & Schmitz, O., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 438-444 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

    Vestergaard, E. T., Hjelholt, A. J., Kuhre, Rune Ehrenreich, Møller, N., Larraufie, P., Gribble, F. M., Reimann, F., Jessen, N., Holst, Jens Juul & Jørgensen, J. O. L., 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2581-2592

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans

    Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, Rune Ehrenreich, Holst, Jens Juul, Rehfeld, Jens Frederik & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage

    Vermeulen, M. A. R., Richir, M. C., Garretsen, M. K., van Schie, A., Ghatei, M. A., Holst, Jens Juul, Heijboer, A. C., Uitdehaag, B. M. J., Diamant, M., Eekhoff, E. M. W., van Leeuwen, P. A. M. & Ligthart-Melis, G. C., Sep 2011, In: Nutrition. 27, 9, p. 897-903 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The role of postprandial releases of insulin and incretin hormones in meal-induced satiety - effect of obesity and weight reduction

    Verdich, C., Toubro, S., Buemann, B. & Holst, Jens Juul, 2001, In: International Journal of Obesity. 25, p. 1206-1214

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

    Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Effect of glucagon-like peptide-1-(7,36)-amide on glucose effectiveness and insulin action in people with type 2 diabetes mellitus

    Vella, A., Shah, P., Basu, R., Basu, A., Holst, Jens Juul & Rizza, R. A., 2000, In: Diabetes. 49, p. 611-617

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Effect of glucagon-like peptide- 1 (7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes

    Vella, A., Shah, P., Basu, R. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 565-572

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates

    Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, S. B., Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men

    Veedfald, Simon, Wu, T., Bound, M., Grivell, J., Hartmann, Bolette, Rehfeld, Jens Frederik, Deacon, Carolyn F., Horowitz, M., Holst, Jens Juul & Rayner, C. K., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4409-4418

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Entero-pancreatic hormone secretion, gastric emptying and glucose absorption after frequently sampled meal tests

    Veedfald, Simon, Rehfeld, Jens Frederik, van Hall, Gerrit, Svendsen, Lars Bo & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. e188-e204 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs

    Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Glucose-Dependent Insulinotropic Polypeptide Is a Pancreatic Polypeptide Secretagogue in Humans

    Veedfald, Simon, Vedtofte, L., Skov-Jeppesen, Kirsa, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Christensen, Mikkel Bring & Holst, Jens Juul, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e502-e510

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Glucose homeostasis and the gastrointestinal tract

    Veedfald, Simon, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, Molecular Nutrition Carbohydrates. Elsevier, p. 3-19 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  41. Published

    Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo

    Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.

    Research output: Contribution to journal › Letter › Research › peer-review

  43. Published

    Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

    Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Gut hormone secretion, gastric emptying and glucose absorption after frequently sampled oral glucose and liquid mixed meal tests in young men: [Meeting Abstract]

    Veedfald, Simon, Rehfeld, Jens Frederik, vanHall, G., Svendsen, Lars Bo & Holst, Jens Juul, 2020, In: Neurogastroenterology and Motility. 32, SI, p. 56 1 p., 146.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  45. Published

    Ghrelin secretion in humans - a role for the vagus nerve?

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial

    Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Major rapid weight loss induces changes in cardiac repolarization

    Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose

    Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes

    Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Plasma glucagon-like peptide 1 and peptide YY levels are not altered in symptomatic fructose-sorbitol malabsorption.

    Valeur, J., Øines, E., Morken, M. H., Holst, Jens Juul & Berstad, A., 2008, In: Scandinavian Journal of Gastroenterology. 43, 10, p. 1212-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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