Thomas Werge
Clinical Professor
- Published
Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome
Starnawska, A., Hansen, C. S., Sparsø, T., Mazin, W., Olsen, L., Bertalan, M., Buil, A., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mortensen, P. B., Pedersen, C. B., Nyegaard, M., Werge, Thomas & Weinsheimer, S., 29 Aug 2017, In: Translational Psychiatry. 7, 11 p., e1221.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Socio-demographic characteristics of adults with self-reported ADHD symptoms in a Danishpopulation of 12,415 blood donors
Høffding, L. K. E., Nielsen, Maria Haahr, Didriksen, Maria, Schow, T., Werge, Thomas, Nielsen, K. R., Erikstrup, C., Pedersen, O. B., Hjalgrim, H., Jepsen, J. R. M., Hansen, T. F., Banasik, K., Ullum, H. & Burgdorf, K., 20 Aug 2018, In: Journal of Psychiatry and Behavioral Sciences. 3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Hughes, T., Sønderby, I. E., Polushina, T., Hansson, L., Holmgren, A., Athanasiu, L., Melbø-Jørgensen, C., Hassani, S., Hoeffding, L. K., Herms, S., Bergen, S. E., Karlsson, R., Song, J., Rietschel, M., Nöthen, M. M., Forstner, A. J., Hoffmann, P., Hultman, C. M., Landén, M., Cichon, S. & 4 others, , 2018, In: Translational Psychiatry. 8, 1, p. 1-12 210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease
Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Kanters, Jørgen K., Nielsen, J., Mors, O., Demur, A. B., Als, T. D., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Kennedy, J., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 1 Dec 2018, In: PLoS ONE. 13, 12, 14 p., e0208828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study
Didriksen, M., Rigas, A. S., Allen, R. P., Burchell, B. J., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., Aug 2017, In: Sleep Medicine. 36, p. 55-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response
Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, Thomas & Sullivan, P. F., 2018, In: Psychological Medicine. 48, 7, p. 1201-1208 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
Hoeffding, L. K. E., Duong, L. T. T., Ingason, A., Rosengren, A., Sorbanski, E., Witt, S. H., Djurovic, S., Andreassen, O. A., Hansen, T., Werge, Thomas & Rasmussen, Henrik Berg, 2016, In: Nordic Journal of Psychiatry. 70, 4, p. 276-279 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare coding variants in ten genes confer substantial risk for schizophrenia
Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M., DeLisi, L. & 91 others, , 2022, In: Nature. 604, 7906, p. 509-516 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression
Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, Merete, Børglum, A. D., Hougaard, D. M., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2022, In: Science Advances. 8, 26, eabi7293.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders
Debost, J. P. G., Thorsteinsson, E., Trabjerg, B., Benros, Michael Eriksen, Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, Thomas, Mortensen, P. B., Agerbo, E. & Vogdrup, L., 2022, In: Acta Psychiatrica Scandinavica. 146, 5, p. 406-419 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A saturated map of common genetic variants associated with human height
Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, , 2022, In: Nature. 610, p. 704–712Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Identification of women at high risk of postpartum psychiatric episodes: A population-based study quantifying relative and absolute risks following exposure to selected risk factors and genetic liability
Johannsen, B. M. W., Larsen, J. T., Liu, X., Madsen, K. B., Mægbæk, M. L., Albiñana, C., Bergink, V., Laursen, T. M., Bech, B. H., Mortensen, P. B., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Agerbo, E., Petersen, L. V. & Munk-Olsen, T., 2024, (E-pub ahead of print) In: Acta Psychiatrica Scandinavica. 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments
Huang, L., Tang, S., Rietkerk, J., Appadurai, V., Krebs, M. D., Schork, A. J., Werge, Thomas, Zuber, V., Kendler, K. & Cai, N., 2024, (Accepted/In press) In: Biological Psychiatry. 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic signature of the pathogenic 22q11.2 deletion identifies carriers and provides insight into systemic dysregulation
Courraud, J., Russo, F., Themudo, G. E., Laursen, S. S., Ingason, A., Hougaard, D. M., Cohen, A. S., Werge, Thomas & Ernst, M., 2023, In: Translational Psychiatry. 13, 7 p., 391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders
Munk-Olsen, T., Di Florio, A., Madsen, K. B., Albiñana, C., Mægbæk, M. L., Bergink, V., Frøkjær, Vibe Gedsø, Agerbo, E., Vilhjálmsson, B. J., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M., Børglum, A. D., Mors, O., Mortensen, P. B. & Liu, X., 2023, In: Translational Psychiatry. 13, 1, 7 p., 346.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life - A Large Prospective Cohort Study on Adult Danes
Didriksen, Maria, Werge, Thomas, Nissen, J., Schwinn, M., Sørensen, E., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Hansen, T. F., Erikstrup, C., Ostrowski, Sisse Rye, Jennum, Poul, Hjalgrim, Henrik, Ullum, H. & Pedersen, Ole Birger Vesterager, 2021, In: International Journal of Environmental Research and Public Health. 18, 14, 14 p., 7610.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic structure of Norway
Mattingsdal, M., Ebenesersdóttir, S. S., Moore, K. H. S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kockum, I., Olsson, T., Alfredsson, L., Helgason, A., Stefánsson, K. & Hovig, E., 2021, In: European Journal of Human Genetics. 29, p. 1710–1718Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study
Fadista, J., Yakimov, V., Võsa, U., Hansen, C. S., Kasela, S., Skotte, L., Geller, F., Courraud, J., Esko, T., Kukuškina, V., Buil, A., Melbye, M., Werge, Thomas, Hougaard, D. M., Milani, L., Bybjerg-Grauholm, J., Cohen, A. S. & Feenstra, B., 2021, In: Scientific Reports. 11, 17463.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits
Martin, J., Khramtsova, E. A., Goleva, S. B., Blokland, G. A. M., Traglia, M., Walters, R. K., Hübel, C., Coleman, J. R. I., Breen, G., Børglum, A. D., Demontis, D., Grove, J., Werge, T., Bralten, J., Bulik, C. M., Lee, P. H., Mathews, C. A., Peterson, R. E., Winham, S. J., Wray, N. & 13 others, , 2021, In: Biological Psychiatry. 89, 12, p. 1127-1137Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample
Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-grauholm, J., Bækvad-hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O. & 3 others, , 2023, In: Biological Psychiatry Global Open Science. 2, 4, p. 400-410 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correlates of phenotypic heterogeneity in autism
Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Caceres, A. S. J., Hayward, H., Crawley, D., Faulkner, J., Sabet, J., Ellis, C., Oakley, B., Loth, E., Charman, T., Murphy, D., Holt, R. & 33 others, , 2022, In: Nature Genetics. 54, 9, p. 1293-1304 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells
Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity
Rajagopal, V. M., Ganna, A., Coleman, J. R. I., Allegrini, A., Voloudakis, G., Grove, J., Als, T. D., Horsdal, H. T., Petersen, L., Appadurai, V., Schork, A., Buil, A., Bulik, C. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, M., Werge, T., Mortensen, P. B. & 7 others, , 2023, In: Scientific Reports. 13, 16 p., 429.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., Alfredsson, L., Andreassen, O. A., Ask, H., Berrettini, W. H., Boehnke, M., Boehm, I., Boni, C., Buehren, K., Bulant, J., Burghardt, R., Chang, X., Cichon, S., Cone, R. D., Courtet, P. & 157 others, , 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 368-378 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & 1 others, , 2023, In: Nature Communications. 14, 16 p., 852.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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