Vilhelm Bohr

Vilhelm Bohr

Affiliate professor, Affiliate Professor


  1. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis

    Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

    Akbari, M., Keijzers, G., Maynard, S., Scheibye-Knudsen, M., Desler, Claus, Hickson, Ian David & Bohr, Vilhelm, Apr 2014, In: DNA Repair. 16, p. 44-53 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging

    Lee, J., Demarest, T. G., Babbar, M., Kim, E. W., Okur, M. N., De, S., Croteau, D. L. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 16, p. 8548-8562

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The DNA repair enzyme, aprataxin, plays a role in innate immune signaling

    Madsen, Helena Borland, Pease, L. I., Scanlan, R. L., Akbari, M., Rasmussen, Lene Juel, Shanley, D. P. & Bohr, Vilhelm, 2023, In: Frontiers in Aging Neuroscience. 15, 17 p., 1290681.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy

    Palikaras, K., Achanta, K., Choi, S., Akbari, M. & Bohr, Vilhelm, 2021, In: Aging. 13, 21, p. 23876-23894 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Pneumococcal meningitis: an evaluation of prognostic factors in 164 cases based on mortality and on a study of lasting sequelae

    Bohr, Vilhelm, Rasmussen, N., Hansen, B., Gade, A., Kjersem, H., Johnsen, N. & Paulson, Olaf B., Mar 1985, In: Journal of Infection. 10, 2, p. 143-57 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD+ pathway

    Maynard, S., Hall, A., Galanos, P., Rizza, S., Yamamoto, T., Gram, H. H., Munk, S. H. N., Shoaib, Muhammad, Sørensen, Claus Storgaard, Bohr, Vilhelm, Lerdrup, Mads, Maya-Mendoza, A. & Bartek, J., 2022, In: Nucleic Acids Research. 50, 17, p. 9948-9965 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mitochondrial PARP1 regulates NAD+-dependent poly ADP-ribosylation of mitochondrial nucleoids

    Lee, J., Hussain, M., Kim, E. W., Cheng, S., Leung, A. K. L., Fakouri, N. B., Croteau, D. L. & Bohr, Vilhelm, 2022, In: Experimental and Molecular Medicine. 54, p. 2135–2147 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. E-pub ahead of print

    Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions

    Hou, Y., Chu, X., Park, J. H., Zhu, Q., Hussain, M., Li, Zhiquan, Madsen, Helena Borland, Yang, B., Wei, Y., Wang, Y., Fang, E. F., Croteau, D. L. & Bohr, Vilhelm, 2024, (E-pub ahead of print) In: Alzheimer's and Dementia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies

    Wang, H. L., Siow, R., Schmauck-Medina, T., Zhang, J., Sandset, P. M., Filshie, C., Lund, Ø., Partridge, L., Bergersen, L. H., Juel Rasmussen, L., Palikaras, K., Sotiropoulos, I., Storm-Mathisen, J., Rubinsztein, D. C., Spillantini, M. G., De Zeeuw, C. I., Watne, L. O., Vyhnalek, M., Veverova, K., Liang, K. X. & 18 others, Tavernarakis, N., Bohr, Vilhelm, Yokote, K., Saarela, J., Nilsen, H., Gonos, E. S., Scheibye-Knudsen, Morten, Chen, G., Kato, H., Selbæk, G., Fladby, T., Nilsson, P., Simonsen, A., Aarsland, D., Lautrup, S., Ottersen, O. P., Cox, L. S. & Fang, E. F., 2024, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 79, 4, 10 p., glae029.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mitochondrial helicases and mitochondrial genome maintenance

    de Souza-Pinto, N. C., Aamann, M. D., Kulikowicz, T., Stevnsner, T. V. & Bohr, Vilhelm, 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 503-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Nutrition and aging

    Cheng, W., Bohr, Vilhelm & de Cabo, R., 1 Apr 2010, In: Mechanisms of Ageing and Development. 131, 4, p. 223-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Base excision repair activities differ in human lung cancer cells and corresponding normal controls

    Karahalil, B., Bohr, Vilhelm & De Souza-Pinto, N. C., 1 Dec 2010, In: Anticancer Research. 30, 12, p. 4963-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mitochondrial DNA repair and association with aging--an update

    Diaz, R. G., Bohr, Vilhelm & Stevnsner, T. V., 1 Aug 2010, In: Experimental Gerontology. 45, 7-8, p. 478-88 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journalReviewResearchpeer-review

  17. A research agenda for aging in China in the 21st century

    Fang, E. F., Scheibye-Knudsen, Morten, Jahn, H. J., Li, J., Ling, L., Guo, H., Zhu, X., Preedy, V., Lu, H., Bohr, Vilhelm, Chan, W. Y., Liu, Y. & Ng, T. B., Nov 2015, In: Ageing Research Reviews. 24, Pt B, p. 197-205 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome

    Okur, M. N., Mao, B., Kimura, R., Haraczy, S., Fitzgerald, T., Edwards-Hollingsworth, K., Tian, J., Osmani, W., Croteau, D. L., Kelley, M. W. & Bohr, Vilhelm, Jan 2020, In: npj Aging and Mechanisms of Disease. 6, 10 p., 1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    NAD+ in Aging: Molecular Mechanisms and Translational Implications

    Fang, E. F., Lautrup, S., Hou, Y., Demarest, T. G., Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 2017, In: Trends in Molecular Medicine. 23, 10, p. 899-916 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

    Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The role of RecQ helicases in non-homologous end-joining

    Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The role of DNA base excision repair in brain homeostasis and disease

    Akbari, M., Morevati, M., Croteau, D. & Bohr, Vilhelm, Aug 2015, In: DNA Repair. 32, p. 172-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

    Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4975983