Thomas Werge
Clinical Professor
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GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C. B. D. W. G. O. T. P. G. C. S. W. G. O. T. P. G. C., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 2019, In: American Journal of Psychiatry. 176, 8, p. 651-660Research output: Contribution to journal › Journal article › Research › peer-review
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Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, Thomas, Garrido, M. I. & Siebner, Hartwig Roman, 2019, In: NeuroImage: Clinical. 22, 101721.Research output: Contribution to journal › Journal article › Research › peer-review
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A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population
Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, 2019, In: Translational Psychiatry. 9, 1, 10 p., 283.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia with Risk for Depression in the Danish Population
Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Agerbo, E., 2019, In: JAMA Psychiatry. 76, 5, p. 516-525 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats
Olsen, L., Klausen, M., Helboe, L., Nielsen, Finn Cilius, Werge, Thomas, Olsen, L., Klausen, M., Helboe, L., Nielsen, Finn Cilius & Werge, Thomas, 2009, In: PLoS ONE. 4, 10, p. e7225 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Ingason, A., Rujescu, D., Cichon, S., Sigurdsson, E., Sigmundsson, T., Pietiläinen, O. P. H., Buizer-Voskamp, J. E., Strengman, E., Francks, C., Muglia, P., Gylfason, A., Gustafsson, O., Olason, P. I., Steinberg, S., Hansen, T. F., Jakobsen, K. D., Rasmussen, H. B., Giegling, I., Möller, H-J., Hartmann, A. & 29 others, , 1 Jan 2011, In: Molecular Psychiatry. 16, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
van Schijndel, J. E., van Loo, K. M. J., van Zweeden, M., Djurovic, S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kallunki, P., Pedersen, J. T. & Martens, G. J. M., 2009, In: Journal of Psychiatric Research. 43, 15, p. 1195-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Kähler, A. K., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., Sep 2011, In: European Neuropsychopharmacology. 21, 9, p. 700-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A rare variant in MYH6 is associated with high risk of sick sinus syndrome
Holm, H., Gudbjartsson, D. F., Sulem, P., Masson, G., Helgadottir, H. T., Zanon, C., Magnusson, O. T., Helgason, A., Saemundsdottir, J., Gylfason, A., Stefansdottir, H., Gretarsdottir, S., Matthiasson, S. E., Thorgeirsson, G. M., Jonasdottir, A., Sigurdsson, A., Stefansson, H., Werge, T., Rafnar, T., Kiemeney, L. A. & 10 others, , 1 Apr 2011, In: Nature Genetics. 43, 4, p. 316-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: A combined analysis of independent samples
Saetre, P., Vares, M., Werge, T., Andreassen, O. A., Arinami, T., Ishiguro, H., Nanko, S., Tan, E. C., Han, D. H., Roffman, J. L., Muntjewerff, J-W., Jagodzinski, P. P., Kempisty, B., Hauser, J., Vilella, E., Betcheva, E., Nakamura, Y., Regland, B., Agartz, I., Hall, H. & 2 others, , Mar 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 2, p. 215-24 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Using electronic patient records to discover disease correlations and stratify patient cohorts
Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia
Carrera, N., Arrojo, M., Sanjuán, J., Ramos-Ríos, R., Paz, E., Suárez-Rama, J. J., Páramo, M., Agra, S., Brenlla, J., Martínez, S., Rivero, O., Collier, D. A., Palotie, A., Cichon, S., Nöthen, M. M., Rietschel, M., Rujescu, D., Stefansson, H., Steinberg, S., Sigurdsson, E. & 12 others, , 2012, In: Biological Psychiatry. 71, 2, p. 169-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cholesterol-induced protein sorting: an analysis of energetic feasibility
Lundbaek, J. A., Andersen, Ove, Werge, Thomas & Nielsen, C., 2003, In: Biophysical Journal. 84, 3, p. 2080-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume
Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B. M., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Kahn, R. S., the Psychiatric Genome-wide Association Study Consortium, Jakobsen, K. D., Hansen, T., Ingason, A., Duong, L., Rasmussen, H. B., Olsen, L., Nordentoft, M., Jürgens, G. & 3 others, , 2013, In: Advances in Biological Psychiatry. 73, 6, p. 525-531Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of CYP2D6 and CYP2C19 polymorphisms on suicidal behavior and substance abuse disorder among patients with schizophrenia: a retrospective study
Kobylecki, C. J., Hansen, T., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B., Werge, T. M., Kobylecki, C. J., Hansen, T. F., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B. & Werge, Thomas, 2008, In: Therapeutic Drug Monitoring. 30, 3, p. 265-70 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Utility and adoption of CYP2D6 and CYP2C19 genotyping and its translation into psychiatric clinical practice
Jürgens, G., Jacobsen, C. B., Rasmussen, H. B., Werge, T., Nordentoft, Merete, Andersen, S. E. & Werge, Thomas, 2012, In: Acta Psychiatrica Scandinavica. 125, 3, p. 228-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and characterization of tandem repeats in exon III of dopamine receptor D4 (DRD4) genes from different mammalian species
Larsen, S. A., Mogensen, L., Dietz, R., Baagøe, H. J., Andersen, M., Werge, Thomas & Rasmussen, H. B., 2005, In: D N A and Cell Biology. 24, 12, p. 795-804 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Runs of homozygosity implicate autozygosity as a schizophrenia risk factor
Keller, M. C., Simonson, M. A., Ripke, S., Neale, B. M., Gejman, P. V., Howrigan, D. P., Lee, S. H., Lencz, T., Levinson, D. F., Sullivan, P. F., Schizophrenia Psychiatric Genome-Wide Association Study Consortium, S. P. G. A. S. C., Hansen, T., Ingason, A., Olsen, L., Schmock, H., Skjødt, C., Thygesen, J. H., Rosengren, A. & Werge, Thomas, 2012, In: P L o S Genetics. 8, 4, p. e1002656Research output: Contribution to journal › Journal article › Research › peer-review
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Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
Jönsson, E. G., Larsson, K., Vares, M., Hansen, T., Wang, August Gabriel, Djurovic, S., Rønningen, K. S., Andreassen, O. A., Agartz, I., Werge, Thomas, Terenius, L. & Hall, H., 2008, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 6, p. 976-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High loading of polygenic risk in cases with chronic schizophrenia
Meier, S. M., Agerbo, E., Maier, R., Pedersen, C. B., Lang, M., Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T., Mors, O., Hougaard, D. M., Børglum, A. D., Wray, N. R. & 5 others, , 2016, In: Molecular Psychiatry. 21, p. 969-974Research output: Contribution to journal › Journal article › Research › peer-review
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Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores
Folkersen, L., Pain, O., Ingason, A., Werge, Thomas, Lewis, C. M. & Austin, J., 2020, In: Frontiers in Genetics. 11, 578.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
Wang, Y., Karstoft, Karen-Inge, Nievergelt, C. M., Maihofer, A. X., Stein, M. B., Ursano, R. J., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Andreassen, O. A., Werge, Thomas, Thompson, W. K. & Andersen, S. B., 2019, In: Journal of Affective Disorders. 252, p. 350-357 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336Research output: Contribution to journal › Journal article › Research › peer-review
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Digital questionnaire platform in the Danish Blood Donor Study
Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quetiapine extended release versus aripiprazole in children and adolescents with first-episode psychosis: the multicentre, double-blind, randomised tolerability and efficacy of antipsychotics (TEA) trial
Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Ruda, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrom, A. D., Nyvang, L., Madsen, S., Werge, T. M., Lange, T., Gluud, C., Skoog, M., Winkel, P., Jepsen, J. R. M. & 3 others, , Aug 2017, In: The Lancet Psychiatry. 4, 8, p. 605-618Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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590
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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340
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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