Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial

    Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

    Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

    Research output: Contribution to journal › Conference abstract in journal › Research

  3. Published

    Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.

    Research output: Contribution to journal › Conference abstract in journal › Research

  4. Published

    The role of glucagon in the acute therapeutic effects of SGLT2 inhibition

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Oxyntomodulin and glicentin may predict the effect of bariatric surgery on food preferences and weight loss

    Nielsen, M. S., Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, le Roux, C. W. & Sjödin, Anders Mikael, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. e1064-e1074

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis

    Gether, L., Thyssen, Jacob Pontoppidan, Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists

    Gasbjerg, Lærke Smidt, Bergmann, N. C., Stensen, S., Christensen, Mikkel Bring, Rosenkilde, Mette, Holst, Jens Juul, Nauck, M. & Knop, Filip Krag, 2020, In: Peptides. 125, 10 p., 170183.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  9. Published

    Secretion of parathyroid hormone may be coupled to insulin secretion in humans

    Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Effects of an intensive lifestyle intervention on the underlying mechanisms of improved glycaemic control in individuals with type 2 diabetes: a secondary analysis of a randomised clinical trial

    Johansen, M. Y., Karstoft, K., MacDonald, C. S., Hansen, K. B., Ellingsgaard, H., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Vaag, A. A., Holst, Jens Juul, Pedersen, Bente Klarlund & Ried-Larsen, M., 2020, In: Diabetologia. 63, p. 2410-2422 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes

    Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    High-Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta-Adrenoceptor Blockade: A Randomized Clinical Trial

    Petersen, K. M., Bøgevig, S., Riis, T., Andersson, N. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Journal of the American Heart Association. 9, 21, 27 p., e016828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects

    Nauck, M. A., Holle, H., Kahle, M., Tytko, A., Deacon, Carolyn F., Holst, Jens Juul & Meier, J. J., 2020, In: Peptides. 125, 170176.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs

    Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)

    Christensen, A. S., Haedersdal, S., Stoy, J., Storgaard, H., Kampmann, U., Forman, Julie Lyng, Seghieri, M., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes Care. 43, 9, p. 2025-2033 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Role of fasting duration and weekday in incretin and glucose regulation

    Clemmensen, K. K. B., Quist, J. S., Vistisen, D., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Holst, Jens Juul, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Færch, K., 2020, In: Endocrine Connections. 9, 4, p. 279-288

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5

    Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Efficacy and safety of meal-time administration of short-acting exenatide for glycaemic control in type 1 diabetes (MAG1C): a randomised, double-blind, placebo-controlled trial

    Johansen, N. J., Dejgaard, T. F., Lund, A., Schluntz, C., Frandsen, C. S., Forman, Julie Lyng, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Madsbad, Sten, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2020, In: The Lancet Diabetes & Endocrinology. 8, 4, p. 313-324 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion

    Xu, S. F. S., Andersen, Daniel Bjørklund, Izarzugaza, J. M. G., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study

    Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

    Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, Hulot, J., Lewinter, C., Pedersen, H. K., Quinquis, B., Rouault, C., Roume, H., Salem, J., Søndertoft, N. B., Touch, S., Dumas, M., Ehrlich, S. D., Galan, P., Gøtze, J. P., Hansen, Torben, Holst, Jens Juul, Køber, Lars Valeur, Letunic, I., Nielsen, J., Oppert, J., Stumvoll, M., Vestergaard, H., Zucker, J., Bork, P., Pedersen, Oluf Borbye, Bäckhed, F., Clément, K., Raes, J. & MetaCardis Consortium, M. C., 2020, In: Nature. 581, 7808, p. 310-315

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Incretin Hormones and Type 2 Diabetes-Mechanistic Insights and Therapeutic Approaches

    Boer, G. A. & Holst, Jens Juul, 2020, In: Biology. 9, 12, 20 p., 473.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Exercise alone and in combination with liraglutide improves cardiorespiratory fitness and physical functioning during weight loss maintenance

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Blond, Martin Bæk, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S290-S290 1 p., 604.

    Research output: Contribution to journal › Conference abstract in journal › Research

  24. Published

    A Potential Role for Endogenous Glucagon in Preventing Post-Bariatric Hypoglycemia

    Lobato, C. B., Pereira, S. S., Guimaraes, M., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Frontiers in Endocrinology. 11, 11 p., 608248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Effect of meal texture on glucose excursions after bariatric surgery

    Hedbäck, N., Hindso, M., Linddal, A. K., Bojsen-Moller, K. N., Jorgensen, N. B., Dirksen, C., Moller, A., Kristiansen, V. B., Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2020, In: Diabetologia. 63, Suppl. 1, p. S203 1 p., 411.

    Research output: Contribution to journal › Conference abstract in journal › Research

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