Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


  1. 2022
  2. Published

    Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

    Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB

    Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, Børglum, A. D., Werge, Thomas, Agerbo, E., Söderhall, C., Altman, M. C., Thysen, A. H., McKennan, C. G., Brix, Susanne, Gern, J. E., Ober, C., Ahluwalia, Tarun Veer Singh, Bisgaard, H., Pedersen, A. G. & Bønnelykke, Klaus, 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

    Fadista, J., Skotte, L., Karjalainen, J., Abner, E., Sørensen, E., Ullum, H., Werge, Thomas, Esko, T., Milani, L., Palotie, A., Daly, M., Melbye, M., Feenstra, B., Geller, F., IPSYCH Grp, I. G. & FinnGen Consortium, F. C., 2022, In: Nature Communications. 13, 11 p., 3200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The population genomic legacy of the second plague pandemic

    Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, Juan, D., Gelabert, P., de-Dios, T., Fotaki, Anna Katerina, Iraeta Orbegozo, Miren, Vågene, Åshild Joanne, Denham, S. D., Christophersen, A., Stenøien, H. K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, T., Kivisild, T., Moseng, O. G., Skar, B., Cheung, C., Sandoval-Velasco, Marcela, Wales, N., Schroeder, Hannes, Campos, P. F., Guðmundsdóttir, V. B., Sicheritz-Pontén, Thomas, Petersen, Bent, Halgunset, J., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, Thomas Folkmann, Werge, Thomas, Willerslev, Eske, Balloux, F., Marques-Bonet, T., Lalueza-Fox, C., Nielsen, Rasmus, Stefánsson, K., Helgason, A. & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 21, p. 4743-4751.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The sequences of 150,119 genomes in the UK Biobank

    Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, Sverrisson, S. T., Sigurdsson, B., Gudjonsson, S. A., Sigurdsson, G. T., Halldorsson, G. H., Sveinbjornsson, G., Norland, K., Styrkarsdottir, U., Magnusdottir, D. N., Snorradottir, S., Kristinsson, K., Sobech, E., Pedersen, Ole Birger Vesterager, Brunak, Søren, Ostrowski, Sisse Rye, Banasik, Karina, Burgdorf, Kristoffer Sølvsten, Didriksen, Maria, Hansen, Thomas Folkmann, Hjalgrim, Henrik, Jemec, Gregor, Jennum, Poul, Jo­hans­son, Pär In­ge­mar , Ostrowski, Sisse Rye, Ullum, H., Werge, Thomas & DBDS Genetic Consortium, D. G. C., 2022, In: Nature. 607

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Selection Landscape and Genetic Legacy of Ancient Eurasians

    Irving-Pease, E., Refoyo Martínez, A., Ingason, A., Pearson, A., Fischer, A., Barrie, W., Sjögren, K-G., Halgren, A. S., Macleod, R., Demeter, F., Henriksen, R. H. A., Vimala, T., McColl, H., Vaughn, A., Stern, A. J., Speidel, L., Scorrano, G., Ramsøe, A., Schork, A. J., Rosengren, A. & 12 others, Zhao, Lei, Kristiansen, K., Sudmant, P. H., Lawson, D. J., Durbin, R., Korneliussen, Thorfinn Sand, Werge, Thomas, Allentoft, Morten Erik, Sikora, Martin, Nielsen, Rasmus, Racimo, Fernando & Willerslev, Eske, 2022, bioRxiv, 26 p.

    Research output: Working paperPreprint

  8. Published

    Genetic assortative mating for schizophrenia and bipolar disorder

    Jefsen, O. H., Nudel, R., Wang, Y., Bybjerg-Grauholm, J., Hemager, N., Christiani, C. A. J., Burton, B. K., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Nordentoft, Merete, Mors, O. & Greve, A. N., 2022, In: European Psychiatry. 65, 1, 7 p., e53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?

    Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structural basis of organic cation transporter-3 inhibition

    Khanppnavar, B., Maier, J., Herborg, Freja, Gradisch, R., Lazzarin, E., Luethi, D., Yang, J. W., Qi, C., Holy, M., Jäntsch, K., Kudlacek, O., Schicker, K., Werge, Thomas, Gether, Ulrik, Stockner, T., Korkhov, V. M. & Sitte, H. H., 2022, In: Nature Communications. 13, 1, 13 p., 6714.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Accumulation of Disadvantages Across Multiple Domains Amongst Subgroups of Children of Parents with Schizophrenia or Bipolar Disorder: Clustering Data from the Danish High Risk and Resilience Study VIA 7

    Krantz, M. F., Ellersgaard, D., Andersen, K. K., Hemager, N., Christiani, C., Spang, K. S., Burton, B. K., Gregersen, M., Søndergaard, A., Greve, A., Gantriis, D. L., Ohland, J., Mortensen, P. B., Werge, T., Nudel, R., Wang, Y., Hougaard, D. M., Plessen, K. J., Bliksted, V., Jepsen, J. R. M. & 3 others, Thorup, Anne, Mors, O. & Nordentoft, Merete, 2022, In: Schizophrenia Bulletin Open. 3, 1, 16 p., sgac010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Life-time Actionable Pharmacogenetic Drug Use: A Population-based Cohort Study in 86 040 Young People with and without Mental Disorders in Denmark

    Lunenburg, C. A. T. C., Ishtiak-Ahmed, K., Werge, Thomas & Gasse, C., 2022, In: Pharmacopsychiatry. 55, 2, p. 95-107

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Enhancing discovery of genetic variants for PTSD through integration of quantitative phenotypes and trauma exposure information

    Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B. & 161 others, Avdibegovic, E., Borglum, A. D., Babic, D., Bμkvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Chen, C., Dale, A. M., Dalvie, S., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Duncan, L. E., Kulenovic, A. D., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gautam, A., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goci, A., Gordon, S. D., Guffanti, G., Hammamieh, R., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X., Karstoft, Karen-Inge, Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J. L., Marmar, C., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., Mehta, D., Mellor, R., Michopoulos, V., Milberg, W., Miller, M. W., Morris, C. P., Mors, O., Mortensen, P. B., Nelson, E. C., Nordentoft, Merete, Norman, S. B., O'Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., Luella van den Heuvel, L., Van Hooff, M., Vermetten, E., Vinkers, C., Voisey, J., Wang, Y., Wang, Z., Werge, Thomas, Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Yehuda, R., Young, K. A., Young, R. M., Zhao, H., Zoellner, L. A., Haas, M., Lasseter, H., Provost, A. C., Salem, R. M., Sebat, J., Shaffer, R. A., Wu, T., Ripke, S., Daly, M. J., Ressler, K. J., Koenen, K. C., Stein, M. B. & Nievergelt, C. M., 1 Apr 2022, In: Biological Psychiatry. 91, 7, p. 626-636 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

    Mattheisen, M., Grove, J., Als, T. D., Martin, J., Voloudakis, G., Meier, S., Demontis, D., Bendl, J., Walters, R., Carey, C. E., Rosengren, A., Strom, N. I., Hauberg, M. E., Zeng, B., Hoffman, G., Zhang, W., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Agerbo, E., Cormand, B. & 14 others, Nordentoft, Merete, Werge, Thomas, Mors, O., Hougaard, D. M., Buxbaum, J. D., Faraone, S. V., Franke, B., Dalsgaard, Søren, Mortensen, P. B., Robinson, E. B., Roussos, P., Neale, B. M., Daly, M. J. & Børglum, A. D., 2022, In: Nature Genetics. 54, p. 1470–1478

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication

    Mikkelsen, Christina, Larsen, M. A. H., Sørensen, E., Hansen, Thomas Folkmann, Mikkelsen, S., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Kessing, Lars Vedel, Werge, Thomas, Ullum, H., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Thørner, L. W. & Didriksen, Maria, 2022, In: Psychiatry Research. 318, 7 p., 114944.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Elucidating the relationship between migraine risk and brain structure using genetic data

    International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Accurate and Effective Detection of Recurrent Copy Number Variants in Large SNP Genotype Datasets

    Montalbano, S., Sánchez, X. C., Vaez, M., Helenius, D., Werge, Thomas & Ingason, A., 2022, In: Current Protocols. 2, 12, 21 p., e621.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

    Mullins, N., Kang, J. E., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M. H., Watson, H. J., Adams, M., Awasthi, S., Gandal, M., Hafferty, J. D., Hishimoto, A., Kim, M., Okazaki, S., Otsuka, I. & 36 others, Ripke, S., Ware, E. B., Bergen, A. W., Berrettini, W. H., Bohus, M., Brandt, H., Chang, X., Chen, W. J., Chen, H. C., Crawford, S., Crow, S., DiBlasi, E., Duriez, P., Fernández-Aranda, F., Fichter, M. M., Gallinger, S., Glatt, S. J., Gorwood, P., Guo, Y., Hakonarson, H., Halmi, K. A., Hwu, H. G., Jain, S., Li, D., Røpke, S., Appadurai, V., Jonsson, L., Schofield, Peter, Nordentoft, Merete, Werge, Thomas, VA Million Veteran Program, V. M. V. P., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C., Eating Disorders Working Group of the Psychiatric Genomics Consortium, E. D. W. G. O. T. P. G. C., German Borderline Genomics Consortium, G. B. G. C. & MVP Suicide Exemplar Workgroup, M. S. E. W., 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions

    Nudel, R., Zetterberg, R., Hemager, N., Christiani, C. A. J., Ohland, J., Burton, B. K., Greve, A. N., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Bybjerg-Grauholm, J., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Mors, O. & Nordentoft, Merete, 2022, In: Behavioral and Brain Functions. 18, 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective

    Nudel, R., Thompson, W. K., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete & Benros, Michael Eriksen, Dec 2022, In: Translational Psychiatry. 12, 1, 9 p., 334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Accounting for age of onset and family history improves power in genome-wide association studies

    Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Privé, F. & 1 others, Vilhjálmsson, B. J., 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

    Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B., Ribasés, M. & 2 others, Børglum, A. D. & Demontis, D., 2022, In: Nature Genetics. 54, 8, p. 1117-1124 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Family disadvantage, gender, and the returns to genetic human capital

    Ronda, V., Agerbo, E., Bleses, D., Mortensen, P. B., Borglum, A., Mors, O., Rosholm, M., Hougaard, D. M., Nordentoft, Merete & Werge, Thomas, Apr 2022, In: Scandinavian Journal of Economics. 124, 2, p. 550-578 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism

    Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Børglum, A. D., Werge, Thomas, Nordentoft, Merete, Mortensen, P. B. & Agerbo, E., 2022, In: Autism Research. 15, 1, p. 171-182

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Infection Polygenic Factors Account for a Small Proportion of the Relationship Between Infections and Mental Disorders

    Shorter, J. R., Meijsen, J., Nudel, R., Krebs, M., Gådin, J., Mikkelsen, D. H., Nogueira Avelar e Silva, R., Benros, Michael Eriksen, Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: Biological Psychiatry. 92, 4, p. 283-290

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Rare coding variants in ten genes confer substantial risk for schizophrenia

    Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M., DeLisi, L. & 91 others, Dodge, S., Escamilla, M. A., Eskelinen, S., Fanous, A. H., Faraone, S. V., Fiorentino, A., Francioli, L., Gabriel, S. B., Gage, D., Gagliano Taliun, S. A., Ganna, A., Genovese, G., Glahn, D. C., Grove, J., Hall, M. H., Hämäläinen, E., Heyne, H. O., Holi, M., Hougaard, D. M., Howrigan, D. P., Huang, H., Hwu, H. G., Kahn, R. S., Kang, H. M., Karczewski, K. J., Kirov, G., Knowles, J. A., Lee, F. S., Lehrer, D. S., Lescai, F., Malaspina, D., Marder, S. R., McCarroll, S. A., McIntosh, A. M., Medeiros, H., Milani, L., Morley, C. P., Morris, D. W., Mortensen, P. B., Myers, R. M., Nordentoft, Merete, O’Brien, N. L., Olivares, A. M., Ongur, D., Ouwehand, W. H., Palmer, D. S., Paunio, T., Quested, D., Rapaport, M. H., Rees, E., Rollins, B., Satterstrom, F. K., Schatzberg, A., Scolnick, E., Scott, L. J., Sharp, S. I., Sklar, P., Smoller, J. W., Sobell, J. L., Solomonson, M., Stahl, E. A., Stevens, C. R., Suvisaari, J., Tiao, G., Watson, S. J., Watts, N. A., Blackwood, D. H., Børglum, A. D., Cohen, B. M., Corvin, A. P., Esko, T., Freimer, N. B., Glatt, S. J., Hultman, C. M., McQuillin, A., Palotie, A., Pato, C. N., Pato, M. T., Pulver, A. E., St. Clair, D., Tsuang, M. T., Vawter, M. P., Walters, J. T., Werge, Thomas, Ophoff, R. A., Sullivan, P. F., Owen, M. J., Boehnke, M., O’Donovan, M. C., Neale, B. M. & Daly, M. J., 2022, In: Nature. 604, 7906, p. 509-516 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 34394780