Thomas Werge
Clinical Professor
- 2020
- Published
FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Baker, J., Bergen, A., Berrettini, W., Birgegård, A., Boden, J., Boehm, I., Boni, C., Boraska Perica, V., Brandt, H. & 44 others, , May 2020, In: Nature Genetics. 52, p. 482-493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 31 others, , May 2020, In: Molecular Psychiatry. 25, p. 1430-1446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia
Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, Merete, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, Thomas, Svenning, J. C. & Horsdal, H. T., 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Erlangsen, A., Appadurai, V., Wang, Y., Turecki, G., Mors, O., Werge, Thomas, Mortensen, P. B., Starnawska, A., Børglum, A. D., Schork, A., Nudel, R., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Thompson, W. K., Nordentoft, Merete & Agerbo, E., 2020, In: Molecular Psychiatry. 25, p. 2410–2421Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between GLP-1 receptor gene polymorphisms with reward Learning, anhedonia, and depression diagnosis
Eser, H. Y., Appadurai, V., Eren, C. Y., Yazici, D., Chen, C. Y., Ongur, D., Pizzagalli, D. A., Werge, Thomas & Hall, M. H., 2020, In: Acta Neuropsychiatrica. 32, 4, p. 218-225Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores
Folkersen, L., Pain, O., Ingason, A., Werge, Thomas, Lewis, C. M. & Austin, J., 2020, In: Frontiers in Genetics. 11, 578.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 31 others, , 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, , 2020, In: Nature Communications. 11, 1, 3368.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic stratification of depression in UK Biobank
Howard, D. M., Folkersen, L., Coleman, J. R., Adams, M. J., Glanville, K., Werge, Thomas, Hagenaars, S. P., Han, B., Porteous, D., Campbell, A., Clarke, T., Breen, G., Sullivan, P. F., Wray, N. R., Lewis, C. M. & McIntosh, A. M., 2020, In: Translational Psychiatry. 10, 1, 8 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale genome-wide association study meta-analysis of cannabis use disorder
Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T. K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., Alexander, J. & 31 others, , 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia: A Randomized Clinical Trial
Jürgens, Gesche, Andersen, Stig Ejdrup, Rasmussen, H. B., Werge, Thomas, Jensen, H. D., Kaas-Hansen, Benjamin Skov & Nordentoft, Merete, 1 Dec 2020, In: JAMA Network Open. 3, 12, p. e2027909Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complement genes contribute sex-biased vulnerability in diverse disorders
Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, , 2020, In: Nature. 582, 7813, p. 577-581 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome
Lahrouchi, N., Tadros, R., Crotti, L., Mizusawa, Y., Postema, P. G., Beekman, L., Walsh, R., Hasegawa, K., Barc, J., Ernsting, M., Turkowski, K. L., Mazzanti, A., Beckmann, B. M., Shimamoto, K., Diamant, U-B., Wijeyeratne, Y. D., Kucho, Y., Robyns, T., Ishikawa, T., Arbelo, E. & 86 others, , 2020, In: Circulation. 142, 4, p. 324-338Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic architecture of sporadic and multiple consecutive miscarriage
Laisk, T., Soares, A. L. G., Ferreira, T., Painter, J. N., Censin, J. C., Laber, S., Bacelis, J., Chen, C. Y., Lepamets, M., Lin, K., Liu, S., Millwood, I. Y., Ramu, A., Southcombe, J., Andersen, M. S., Yang, L., Becker, C. M., Børglum, A. D., Gordon, S. D., Bybjerg-Grauholm, J. & 35 others, , 2020, In: Nature Communications. 11, 5980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Duffy-null genotype and risk of infection
Legge, S. E., Christensen, R. H., Petersen, L., Pardiñas, A. F., Bracher-Smith, M., Knapper, S., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Mortensen, P. B., Owen, M. J., O'Donovan, M. C., Benros, Michael Eriksen & Walters, J. T. R., 2020, In: Human Molecular Genetics. 29, 20, p. 3341-3349 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic liability to major depression and risk of childhood asthma
Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Mortensen, P. B. & Agerbo, E., 2020, In: Brain, Behavior, and Immunity. 89, p. 433-439 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genomics of the Viking world: [incl. correction]
Margaryan, A., Lawson, D. J., Sikora, M., Racimo, F., Rasmussen, S., Moltke, I., Cassidy, L. M., Jørsboe, E., Ingason, A., Pedersen, M. W., Korneliussen, T., Wilhelmson, H., Buś, M. M., de Barros Damgaard, P., Martiniano, R., Renaud, G., Bhérer, C., Moreno-Mayar, J. V., Fotakis, A. K., Allen, M. & 30 others, , 2020, In: Nature. 585, 7825, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control
Maurer, G. W., Malita, Alina, Nagy, S., Koyama, Takashi, Werge, Thomas, Halberg, Kenneth Veland, Texada, Michael James & Rewitz, Kim, 2020, In: PLOS Genetics. 16, 4, 31 p., e1008727.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between Mental Disorders and Subsequent Medical Conditions
Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E., Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P., Debost, J-C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C., Laursen, T. M., Lim, C. C. W., Mors, O., Mortensen, P. B., Musliner, K. L. & 18 others, , 2020, In: The New England Journal of Medicine. 382, 18, p. 1721-1731 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia
Monroe, T. O., Garrett, M. E., Kousi, M., Rodriguiz, R. M., Moon, S., Bai, Y., Brodar, S. C., Soldano, K. L., Savage, J., Hansen, T. F., Muzny, D. M., Gibbs, R. A., Barak, L., Sullivan, P. F., Ashley-Koch, A. E., Sawa, A., Wetsel, W. C., Werge, Thomas & Katsanis, N., 2020, In: Nature Communications. 11, 1, 14 p., 5903.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 332 others, , 2020, In: Addiction Biology (Online). 26, 1, 20 p., e12880.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life
Musliner, K. L., Krebs, M. D., Albiñana, C., Vilhjalmsson, B., Agerbo, E., Zandi, P. P., Hougaard, D. M., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Mortensen, P. B. & Østergaard, S. D., 2020, In: American Journal of Psychiatry. 177, 10, p. 936-943 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness
Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, Mar 2020, In: Human Genetics. 139, p. 593-604Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Language deficits in specific language impairment, attention deficit/hyperactivity disorder, and autism spectrum disorder: An analysis of polygenic risk
Nudel, R., Christiani, C. A. J., Ohland, J., Uddin, M. J., Hemager, N., Ellersgaard, D. V., Spang, K. S., Burton, B. K., Greve, A. N., Gantriis, D. L., Bybjerg-Grauholm, J., Jepsen, J. R. M., Thorup, Anne, Mors, O., Nordentoft, Merete & Werge, Thomas, 2020, In: Autism Research. 13, 3, p. 369-381Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study
Nudel, R., Christiani, C. A. J., Ohland, J., Uddin, M. J., Hemager, N., Ellersgaard, D., Spang, K. S., Burton, B. K., Greve, A. N., Gantriis, D. L., Bybjerg-Grauholm, J., Jepsen, J. R. M., Thorup, Anne, Mors, O., Werge, Thomas & Nordentoft, Merete, 2020, In: BMC Neuroscience. 21, 14 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression
Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Mortensen, P. B., Agerbo, E. & Horsdal, H. T., 2020, In: British Journal of Psychiatry. 217, 1, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A major role for common genetic variation in anxiety disorders
Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, , 2020, In: Molecular Psychiatry. 25, p. 3292–3303Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic prediction of school performance in individuals with and without psychiatric disorders
Rajagopal, V. M., Trajberg, B. B., Grove, J., Horsdal, H. T., Petersen, L., Bulik, C. M., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Agerbo, E., Borglum, A. D., Demontis, D. & iPSYCH-Broad Consortium, I. C., 2020, In: Behavior Genetics. 50, 6, p. 476-477 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Cerebral small vessel disease genomics and its implications across the lifespan
Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, , 2020, In: Nature Communications. 11, 1, 18 p., 6285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J. Y., Peng, M., Collins, R., Grove, J., Klei, L., Stevens, C., Reichert, J., Mulhern, M. S., Artomov, M., Gerges, S., Sheppard, B., Xu, X., Bhaduri, A., Norman, U., Brand, H. & 32 others, , 2020, In: Cell. 180, 3, p. 568-584.e23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, , 2020, In: Nature Communications. 11, 1, 2301.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of the genetic liability on the association between infections and autism
Shorter, J., Krebs, M., Ingason, A., Benros, Michael Eriksen, Thompson, W. & Werge, Thomas, Dec 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 719-720 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
Wang, Y., Nudel, R., Benros, Michael Eriksen, Skogstrand, K., Fishilevich, S., Lancet, D., Sun, J., Hougaard, D. M., Andreassen, O. A., Mortensen, P. B., Buil, A., Hansen, Thomas Folkmann, Thompson, W. K., Werge, Thomas & iPSYCH-BROAD, I., 2020, In: PLOS Genetics. 16, 11, e1009163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic liability to ADHD and substance use disorders in individuals with ADHD
Wimberley, T., Agerbo, E., Horsdal, H. T., Ottosen, C., Brikell, I., Als, T. D., Demontis, D., Børglum, A. D., Nordentoft, Merete, Mors, O., Werge, Thomas, Hougaard, D., Bybjerg-Grauholm, J., Hansen, M. B., Mortensen, P. B., Thapar, A., Riglin, L., Langley, K. & Dalsgaard, S., 2020, In: Addiction. 115, 7, p. 1368-1377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder
Østergaard, S. D., Trabjerg, B. B., Als, T. D., Climent, C. A., Privé, F., Vilhjálmsson, B. J., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Demontis, D., Mortensen, P. B., Børglum, A. D., Mors, O. & Agerbo, E., 2020, In: Translational Psychiatry. 10, 1, 335.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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