Holger Grohganz

Holger Grohganz

Associate Professor

ORCID: 0000-0002-0482-1397

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  1. Published

    Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

    Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling

    Wang, Y., Rades, Thomas & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 1, 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Controlling production process: incorporating analytical methods

    Grohganz, Holger & Rantanen, Jukka, 2008, In: Pharma focus Asia. 8, p. 82-83

    Research output: Contribution to journal › Journal article › Communication

  4. Published

    Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

    Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Design of experiments approach on the compaction properties of co-amorphous tablets

    Engelsing, F., Buchart, L. & Grohganz, Holger, 2023, In: Pharmaceutical Development and Technology. 28, 9, p. 907-914

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 2012, In: A A P S PharmSciTech. 13, 3, p. 747-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

    Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis

    Chieng, N., Trnka, H., Bøtker, Johan Peter, Pikal, M., Rantanen, Jukka & Grohganz, Holger, 18 Jul 2013, In: International Journal of Pharmaceutics. 454, 1, p. 167-173 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems

    Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Development of a screening method for co-amorphous formulations of drugs and amino acids

    Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dipeptides as co-formers in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media

    Heikkinen, A. T., DeClerck, L., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan

    Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

    Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Emerging trends in the stabilization of amorphous drugs

    Laitinen, R., Löbmann, Korbinian, Strachan, C. J., Grohganz, Holger & Rades, Thomas, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

    Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 21 Feb 2013, In: A A P S PharmSciTech. 14, 2, p. 901 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  18. Published

    Exploring the chemical space for freeze-drying excipients

    Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Formation mechanism of coamorphous drug−amino acid mixtures

    Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Formation of mannitol hemihydrate in freeze-dried protein formulations-A design of experiment approach

    Larsen, H. M. L., Trnka, H. & Grohganz, Holger, 2 Jan 2014, In: International Journal of Pharmaceutics. 460, 1-2, p. 45-52 8 p.

    Research output: Contribution to journal › Journal article › Research

  21. Published

    Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17

    Research output: Contribution to journal › Journal article › Communication

  22. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

    Trnka, H., Wu, J., van de Weert, Marco, Grohganz, Holger & Rantanen, Jukka, Dec 2013, In: Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation

    Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO

    Doreth, M., Löbmann, Korbinian, Grohganz, Holger, Holm, R., Lopez De Diego, H., Rades, Thomas & Priemel, P. A., 1 Feb 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 32–40 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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