Olaf Nielsen
Professor
Functional Genomics
Ole Maaløes Vej 5
2200 København N.
- Published
A context-dependent and disordered ubiquitin-binding motif
Dreier, Jesper Elmsted, Prestel, Andreas, Martins, J. M., Brøndum, S. S., Nielsen, Olaf, Garbers, Anna Engstrøm, Suga, H., Boomsma, Wouter, Rogers, Joseph Matthew, Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.Research output: Contribution to journal › Journal article › Research › peer-review
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A third gene, mfm3, for M-factor pheromone in fission yeast. Abstract. GSA-Meeting, Wisconsin, Madison, USA
Egel, R., Kjærulff, S., Nielsen, Olaf & Davey, J., 1993, 1993 Yeast Genetics and Molecular Biology Meeting. Abstracts Volume. USA, p. 101AResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe
Christensen, P. U., Davis, K., Nielsen, O., Davey, W. J. & Nielsen, Olaf, 1 Feb 1997, In: F E M S Microbiology Letters. 147, 1, p. 97-102 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An IPTG-inducible derivative of the fission yeast nmt promoter
Kjærulff, S. & Nielsen, Olaf, 2015, In: Yeast. 32, p. 469-478 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of RNA metabolism in fission yeast
Wise, J. A. & Nielsen, Olaf, May 2017, In: Cold Spring Harbor Protocols. 2017, 5, p. 365-372 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of the structural genes encoding M-factor in the fission yeast Schizosaccharomyces pombe: identification of a third gene, mfm3
Kjaerulff, S., Davey, W. J., Nielsen, O. & Nielsen, Olaf, 1 Jun 1994, In: Molecular and Cellular Biology. 14, 6, p. 3895-905 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of pheromone production and response in fission yeast by a halo test of induced sporulation
Egel, Richard, Willer, M., Kjaerulff, S., Davey, W. J., Nielsen, O. & Nielsen, Olaf, 1 Oct 1994, In: Yeast. 10, 10, p. 1347-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast
Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner
Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COP9 signalosome: a provider of DNA building blocks
Nielsen, Olaf, 15 Jul 2003, In: Current Biology. 13, 14, p. R565-7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1.
Kjaerulff, S., Andersen, N. R., Borup, M. T. & Nielsen, Olaf, 2007, In: Genes & Development. 21, 3, p. 347-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell differentiation by interaction of two HMG-box proteins: Mat1-Mc activates M cell-specific genes in S.pombe by recruiting the ubiquitous transcription factor Ste11 to weak binding sites
Kjaerulff, S., Dooijes, D., Clevers, H., Nielsen, O. & Nielsen, Olaf, 1 Jul 1997, In: E M B O Journal. 16, 13, p. 4021-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell differentiation by interaction of two HMG-box proteins: The fission yeast Mat1-Mc protein recruits the Stell transcription factor to weak binding sites
Kjærulff, S., Dooijes, D., Clevers, H. & Nielsen, Olaf, 1997, Yeast Cell Biology. Cold Spring Harbor Laboratory, p. 128Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Characterization of cell fusion in Schizosaccharomyces pombe. Abstr. European Congr. for Molecular Cell Biology, Brighton, England, 22.-25. Marts
Petersen, J., Hagan, I., Egel, R. & Nielsen, Olaf, 1997, ECBO 97. p. 22 (B28)Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Characterization of cell fusion in Schizosoccaromyces pombe. Abstr. 18th Intern. Conf. on Yeast Genetics and Molecular Biology, Stellenbosch, South Africa, March 31.-April 5., 1997
Petersen, J., Hagan, I., Egel, R. & Nielsen, Olaf, 1997, In: Yeast. 13 (special issue), p. S149/P91Research output: Contribution to journal › Journal article › Research
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Characterization of fus1 in Schizosaccharomyces pombe: A developmentally controlled function needed for conjugation (abstr. 17th Intern. Conf. on Yeast Genetics and Molecular Biology, Lissabon,juni95)
Petersen, J., Weilguny, D., Egel, R. & Nielsen, Olaf, 1995, In: Yeast. 11 (special issue), p. S82Research output: Contribution to journal › Journal article › Research
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Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation
Petersen, J., Weilguny, D., Egel, Richard, Nielsen, O. & Nielsen, Olaf, 1 Jul 1995, In: Molecular and Cellular Biology. 15, 7, p. 3697-707 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of meiotic mutants reveals multiole roles for telomeres during meiosis
Tuzon, C. T., Nielsen, Olaf & Cooper, J. P., 2002.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Characterization of the fission yeast p127 Xeroderma Pigmentosum homologue
Hansen, H. A., Slaaby, R., Fleck, O. & Nielsen, Olaf, 2002.Research output: Contribution to conference › Conference abstract for conference › Research
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Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs
Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive profiling of the fission yeast transcription start site activity during stress and media response
Thodberg, Malte, Thieffry, A., Lange, Jette Bornholdt, Boyd, M., Holmberg, Christian, Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, Olaf & Sandelin, Albin Gustav, 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Constitutive Activation of the Fission Yeast Pheromone-Responsive Pathway Induces Ectopic Meiosis and Reveals Ste11 as a Mitogen-Activated Protein Kinase Target
Kjærulff, S., Lautrup-Larsen, I., Truelsen, S., Pedersen, M. & Nielsen, Olaf, 2005, In: Molecular and Cellular Biology. 25, 5, p. 2045-2059Research output: Contribution to journal › Journal article › Research › peer-review
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Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA repair
Fleck, O. & Nielsen, Olaf, 1 Feb 2004, In: Journal of Cell Science. 117, Pt 4, p. 515-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ddb1 controls genome stability and meiosis in fission yeast
Holmberg, Christian, Fleck, O., Hansen, H. A., Liu, C., Slaaby, R., carr, A. M. & Nielsen, Olaf, 2005, In: Genes & Development. 19, 7, p. 853-862Research output: Contribution to journal › Journal article › Research › peer-review
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Den nye arv - historien om dna dna dna ...
Nielsen, Olaf, 1999, In: Hovedområdet. 3, p. 14-15Research output: Contribution to journal › Journal article › Research
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Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication
Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe
Petersen, J., Nielsen, O., Egel, Richard, Hagan, I. M. & Nielsen, Olaf, 1 Apr 1998, In: Journal of Cell Science. 111 ( Pt 7), p. 867-76 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation
Petersen, J., Nielsen, O., Egel, Richard, Hagan, I. M. & Nielsen, Olaf, 1 Jun 1998, In: Journal of Cell Biology. 141, 5, p. 1217-28 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fission yeast goes synthetic.
Nielsen, Olaf, 2007, In: Nature Methods. 4, 10, p. 777-8 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A
Møller, M. B., Kania, Per, Ino, Y., Gerdes, Anne-Marie Axø, Nielsen, Olaf, Louis, D. N., Skjødt, K. & Pedersen, N. T., May 2000, In: Leukemia. 14, 5, p. 898-904 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs
Richard, S., Almeida, J. M. G. C. F., Cissé, O. H., Luraschi, A., Nielsen, Olaf, Pagni, M. & Hauser, P. M., 2018, In: mBio. 9, 1, 10 p., e02201-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional conservation between Schizosaccharomyces pombe ste8 and Saccharomyces cerevisiae STE11 protein kinases in yeast signal transduction
Styrkársdóttir, U., Egel, Richard, Nielsen, O. & Nielsen, Olaf, 1 Oct 1992, In: Molecular and General Genetics MGG. 235, 1, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide identification of pheromone-targeted transcrption in fission yeast
Xue-Franzen, Y., Kjærulff, S., Holmberg, Christian, Wright, A. & Nielsen, Olaf, 2006, In: BMC Genomics. 7, p. 303Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gær som model for menneskeceller
Nielsen, Olaf, 1994, In: Naturligvis. p. 27-29Research output: Contribution to journal › Journal article › Research
- Published
Identification of the transporter for the M-factor mating pheromone in fission yeast
Davey, W. J., Christensen, P. U., Nielsen, O. & Nielsen, Olaf, 1 May 1997, In: Biochemical Society Transactions. 25, 2, p. 224SResearch output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of a protein-kinase cascade in signal transduction of fission yeast. Abstr. 16th Intern. Conf. on Yeast Genetics and Molecular Biology, Wien, Østrig, 15.-21. aug. 1992
Styrkársdóttir, U., Lautrup-Larsen, I. & Nielsen, Olaf, 1992, In: Yeast. 8 (special issue), p. S377Research output: Contribution to journal › Journal article › Research
- Published
Isolation and characterization of the fus1 gene from Schizosaccharomyces pombe. Abstract. GSA-Meeting, Wisconsin, Madison, USA
Nielsen, Olaf, Petersen, J., Egel, R. & Weilguny, D., 1993, 1993 Yeast Genetics and Molecular Biology Meeting. Abstracts Volume. USA, p. 104AResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Isolation and characterization of the rik1 gene from Schizosaccharomyces pombe. Abstract. GSA-Meeting, Wisconsin, Madison, USA
Borgstrøm, B., Weilguny, D., Egel, R. & Nielsen, Olaf, 1993, 1993 Yeast Genetics and Molecular Biology Meeting. Abstracts Volume. USA, p. 124AResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Isolation and characterization of the rik1*O+ gene from the fission yeast Schizosaccharomyces pombe. Abstract 25th Lunteren Lectures, Lunteren, The Netherlands, 20.-23. september 1994
Borgstrøm, B., Weilguny, D., Egel, R. & Nielsen, Olaf, 1994, Book of Abstracts: Chromatin, Structure and the Control of Gene Expression.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Mangel på DNA-byggesten kan give kræft.
Holmberg, Christian & Nielsen, Olaf, 2005, In: Aktuel Naturvidenskab. 3, p. 22-23Research output: Contribution to journal › Journal article › Research
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Mapping the double-strand breaks at the mating-type locus in fission yeast by genomic sequencing
Nielsen, O., Egel, Richard & Nielsen, Olaf, 1 Jan 1989, In: E M B O Journal. 8, 1, p. 269-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mat1-Mc activates M-cell specific genes in Schizosaccharomyces pombe by recruiting the stell transcription factor to weak binding sites
Kjærulff, S., Dooijes, D., Clevers, H. & Nielsen, Olaf, 1997, In: Yeast. 13 (special issue), p. s162/p101Research output: Contribution to journal › Journal article › Research
- Published
Mating type Control and differenctiation
Nielsen, Olaf, 2004, The Molecular Biology of Schizosaccharomyces pombe, genetics, genomics and beyond. Berlin, Springer: <Forlag uden navn>, p. 281-2961Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- Published
Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis
Christensen, P. U., Bentley, N. J., Martinho, R. G., Nielsen, O., Carr, A. & Nielsen, Olaf, 14 Mar 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 6, p. 2579-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in cyr1 and pat1 reveal pheromone-induced G1 arrest in the fission yeast Schizosaccharomyces pombe
Davey, W. J., Nielsen, O. & Nielsen, Olaf, 1 Aug 1994, In: Current Genetics. 26, 2, p. 105-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in cyr1 nad pat1 reveal pheromone-induced G*U1 arrest in the fission yeast Schizosaccharomyces pombe
Davey, J. & Nielsen, Olaf, 1994, In: Current Genetics. 26, p. 105-112Research output: Contribution to journal › Journal article › Research
- Published
New vectors in fission yeast: application for cloning the his2 gene
Weilguny, D., Praetorius, M., Carr, A., Egel, Richard, Nielsen, O. & Nielsen, Olaf, 1 Mar 1991, In: Gene. 99, 1, p. 47-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.
Nielsen, Olaf & Løbner-Olesen, Anders, 2008, In: EMBO Reports. 9, 2, p. 151-156 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pheromone Procedures in Fission Yeast
Davey, J., Egel, R. & Nielsen, Olaf, 1995, Methods in Molecular Genetics. Vol 6. Microbial Gene Techniques. London: Academic Press, p. 247-263Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.
Research output: Contribution to journal › Review › Research › peer-review
Published -
1835
downloads
Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1552
downloads
C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner
Research output: Contribution to journal › Journal article › Research › peer-review
Published