Thomas Werge
Clinical Professor
- 2018
- Published
22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response
Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties
St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, , 2018, In: Molecular Psychiatry. 23, 2, p. 263-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age at first birth in women is genetically associated with increased risk of schizophrenia
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, , 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of shared heritability in common disorders of the brain
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, , 2018, In: Science. 360, 6395, 40 p., eaap8757.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomes from Iceland reveal the making of a human population
Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, , 2018, In: Science. 360, 6392, p. 1028-1032 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum
LaBianca, S., Pagsberg, Anne Katrine, Jakobsen, K. D., Demur, A. B., Bartalan, M., LaBianca, J. & Werge, Thomas, 2018, In: Journal of Autism and Developmental Disorders. 48, 10, p. 3629-3636 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M. & 51 others, , 2018, In: Nature Genetics. 50, p. 381-389Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comorbidity of migraine with ADHD in adults
Hansen, Thomas Folkmann, Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, Thomas & Burgdorf, K., 2018, In: BMC Neurology. 18, 1, p. 1-9 147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Hughes, T., Sønderby, I. E., Polushina, T., Hansson, L., Holmgren, A., Athanasiu, L., Melbø-Jørgensen, C., Hassani, S., Hoeffding, L. K., Herms, S., Bergen, S. E., Karlsson, R., Song, J., Rietschel, M., Nöthen, M. M., Forstner, A. J., Hoffmann, P., Hultman, C. M., Landén, M., Cichon, S. & 4 others, , 2018, In: Translational Psychiatry. 8, 1, p. 1-12 210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS. O4.6.
Benros, Michael Eriksen, Nudel, R., Wang, Y., Appadurai, V., Schork, A., Agerbo, E., Werge, Thomas, Nordentoft, Merete, Mortensen, P., Buil, A. & Thompson, W., 2018, In: Schizophrenia Bulletin. 44, Suppl. 1, p. S85 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis
Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., iPSYCH-Broad ASD Group, the IMAGEN consortium, Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Burke Quinlan, E., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M. L. & 31 others, , 2018, In: Translational Psychiatry. 8, 1, 204.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, Thomas & Sullivan, P. F., 2018, In: Psychological Medicine. 48, 7, p. 1201-1208 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, T. M. D. D. W. G. O. T. P. G. C., 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder
Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., Thomson, P. A., Porteous, D., Campbell, A., Smith, B. H., Black, C., Padmanabhan, S., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M. & 32 others, , 2018, In: PLOS ONE. 13, 12, p. 1-29 e0209160.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study
Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., Sanchez, X. C., Hoeffding, L. K., Schmock, H., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Daly, M. J., Neale, B. M., Pedersen, M. G., Agerbo, E., Mors, O., Børglum, A., Nordentoft, M., Hougaard, D. M., Mortensen, P. B. & 4 others, , 2018, In: The Lancet Psychiatry. 5, 7, p. 573-580 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum
Ganna, A., Satterstrom, F. K., Zekavat, S. M., Das, I., Kurki, M. I., Churchhouse, C., Alfoldi, J., Martin, A. R., Havulinna, A. S., Byrnes, A., Thompson, W. K., Nielsen, P. R., Karczewski, K. J., Saarentaus, E., Rivas, M. A., Gupta, N., Pietiläinen, O., Emdin, C. A., Lescai, F., Bybjerg-Grauholm, J. & 28 others, , 2018, In: American Journal of Human Genetics. 102, 6, p. 1204-1211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
Fan, C. C., McGrath, J. J., Appadurai, V., Buil, A., Gandal, M. J., Schork, A. J., Mortensen, P. B., Agerbo, E., Geschwind, S. A., Geschwind, D., Werge, Thomas, Thompson, W. K. & Pedersen, C. B., 2018, In: Nature Communications. 9, 7 p., 5296.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods
Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., Larsen, J. T., Petersen, L., Watson, H. J., Yilmaz, Z., Kirk, K. M., Gordon, S., Leppä, V. M., Martin, F. C., Whiteman, D. C., Olsen, C. M., Werge, T. M., Pedersen, N. L., Kaye, W., Bergen, A. W. & 26 others, , 2018, In: Contemporary Clinical Trials. 74, p. 61-69 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders
Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
Haney, J. R., CommonMind Consortium, C. C., PsychENCODE Consortium, P. C. & iPSYCH-BROAD Working Group, I. W. G., 9 Feb 2018, In: Science. 359, 6376, p. 693-697 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register
Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 15 Mar 2018, In: Biological Psychiatry. 83, 6, p. 492-498Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated polygenic burden for autism is associated with differential DNA methylation at birth
Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., Andrews, S. V., Hougaard, D. M., Bresnahan, M., Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M., Mortensen, P. B., Børglum, A. D., Werge, T., Pedersen, M. G., Nordentoft, M., Buxbaum, J., Fallin, M. D., Bybjerg-Grauholm, J. & 2 others, , 28 Mar 2018, In: Genome Medicine. 10, 13 p., 19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors
Didriksen, Maria, Allen, R. P., Burchell, B. J., Thørner, L. W., Rigas, A. S., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nielsen, K., Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., May 2018, In: Sleep Medicine. 45, p. 124-131 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder
Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Socio-demographic characteristics of adults with self-reported ADHD symptoms in a Danishpopulation of 12,415 blood donors
Høffding, L. K. E., Nielsen, Maria Haahr, Didriksen, Maria, Schow, T., Werge, Thomas, Nielsen, K. R., Erikstrup, C., Pedersen, O. B., Hjalgrim, H., Jepsen, J. R. M., Hansen, T. F., Banasik, K., Ullum, H. & Burgdorf, K., 20 Aug 2018, In: Journal of Psychiatry and Behavioral Sciences. 3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, I. M. S. G. C. E. A. C. C. E., Sellebjerg, Finn Thorup, Ullum, H. & Werge, Thomas, 29 Nov 2018, In: Cell. 175, 6, p. 1679-1687.e7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease
Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Kanters, Jørgen K., Nielsen, J., Mors, O., Demur, A. B., Als, T. D., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Kennedy, J., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 1 Dec 2018, In: PLoS ONE. 13, 12, 14 p., e0208828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., Kanters, Jørgen K., Nielsen, J., Theisen, M., Mors, O., Kennedy, J., Als, T. D., Demur, A. B., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 13 Dec 2018, In: PLoS ONE. 13, 12, 26 p., e0208829.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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594
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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