Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Glucose and Amino Acid Metabolism in Mice Depend Mutually on Glucagon and Insulin Receptor Signaling
Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Rosenkilde, Mette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 4, p. E660-E673Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.Research output: Contribution to journal › Journal article › Research › peer-review
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Alanine, arginine, cysteine, and proline, but not glutamine, are substrates for, and acute mediators of, the liver-α-cell axis in female mice
Galsgaard, Katrine Douglas, Jepsen, Sara Lind, Kjeldsen, Sasha Alexandra Sampson, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E920-E929 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon receptor signaling is not required for N-carbamoyl glutamate- And L-citrulline-induced ureagenesis in mice
Galsgaard, Katrine Douglas, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Winther-Sørensen, Marie, Stojanovska, E., Vilstrup, H., Ørskov, Cathrine, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 5, p. G912-G927Research output: Contribution to journal › Journal article › Research › peer-review
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Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis
Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103Research output: Contribution to journal › Journal article › Research › peer-review
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The liver–alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels
Gar, C., Haschka, S. J., Kern-Matschilles, S., Rauch, B., Sacco, V., Prehn, C., Adamski, J., Seissler, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Lechner, A., 2021, In: Diabetologia. 64, 3, p. 512-520Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2
Gasbjerg, Lærke Smidt, Hartmann, Bolette, Christensen, Mikkel Bring, Lanng, A. R., Vilsbøll, Tina, Jørgensen, Niklas Rye, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 130, 6 p., 115079 .Research output: Contribution to journal › Journal article › Research › peer-review
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Dose-dependent efficacy of the glucose-dependent insulinotropic polypeptide (GIP)receptor antagonistGIP(3-30)NH2 on GIP actions in humans
Gasbjerg, Lærke Smidt, Bari, E. J., Stensen, S., Hoe, B., Lanng, A. R., Mathiesen, D. S., Christensen, Mikkel Bring, Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 1, p. 68-74Research output: Contribution to journal › Journal article › Research › peer-review
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GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917Research output: Contribution to journal › Journal article › Research › peer-review
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GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e725-e738 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists
Gasbjerg, Lærke Smidt, Bergmann, N. C., Stensen, S., Christensen, Mikkel Bring, Rosenkilde, Mette, Holst, Jens Juul, Nauck, M. & Knop, Filip Krag, 2020, In: Peptides. 125, 10 p., 170183.Research output: Contribution to journal › Review › Research › peer-review
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The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide
Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092Research output: Contribution to journal › Review › Research › peer-review
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Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents
Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome
Gebhard, B., Holst, Jens Juul & Biegelmayer, C., 2001, In: Digest Dis Sci. 46, p. 1915-1923Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia
Gejl, M., Egefjord, L., Lerche, S., Vang, K., Bibby, B. M., Holst, Jens Juul, Mengel, A., Møller, N., Rungby, J., Brock, B. & Gjedde, Albert, Dec 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2146-2152 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia
Gejl, M., Lerche, S., Mengel, A., Møller, N., Bibby, B. M., Smidt, K., Brock, Birgitte, Søndergaard, H., Bøtker, H. E., Gjedde, Albert, Holst, Jens Juul, Hansen, S. B. & Rungby, J., 2014, In: PLOS ONE. 9, 1, p. 1-10 10 p., e83758.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 (GLP-1) raises blood-brain glucose transfer capacity and hexokinase activity in human brain
Gejl, M., Lerche, S., Egefjord, L., Brock, Birgitte, Møller, N., Vang, K., Rodell, A., Bibby, B. M., Holst, Jens Juul, Rungby, J. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-9 10 p., 2.Research output: Contribution to journal › Journal article › Research › peer-review
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Lower blood glucose, hyperglucagonemia and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huan, H., Cui, L., Tang, B. L., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Jelicks, L. A., Serup, P., Nishimura, E. & Charron, M. J., 2003, In: Proc Natl Sci. 100, p. 1438-1443Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass
Gelling, R. W., Vuguin, P. M., Du, X. Q., Cui, L., Rømer, J., Pederson, R. A., Leiser, M., Sørensen, H., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Fleischer, N., McIntosh, C. H. S., Nishimura, E. & Charron, M. J., 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 3, p. E695-707Research output: Contribution to journal › Journal article › Research › peer-review
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Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women
Gentile, C. L., Ward, E., Holst, Jens Juul, Astrup, A., Ormsbee, M. J., Connelly, S. & Arciero, P. J., 2015, In: Nutrition Journal. 14, 10 p., 113.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine
Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.Research output: Contribution to journal › Journal article › Research › peer-review
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Colesevelam has no acute effect on postprandial GLP-1 levels but abolishes gallbladder refilling
Gether, I. M., Bahne, E., Nerild, H. H., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 190, 4, p. 314-326 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake
Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390Research output: Contribution to journal › Journal article › Research › peer-review
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Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis
Gether, L., Thyssen, Jacob Pontoppidan, Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of topical corticosteroid vs. tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis - a randomized controlled study
Gether, L., Storgaard, H., Kezic, S., Jakasa, I., Hartmann, Bolette, Skov-Jeppesen, Kirsa, Holst, Jens Juul, Pedersen, A. J., Forman, Julie Lyng, van Hall, Gerrit, Sørensen, O. E., Skov, Lone, Røpke, Mads Almose, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, 2023, In: Allergy. 78, 7, p. 1964-1979 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomics reveals the effects of sustained weight loss on the human plasma proteome
Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of the long-term effects of LIiraglutide and Glimepiride monotherapy on bone mineral density in patients with type 2 diabetes
Gilbert, M. P., Marre, M., Holst, Jens Juul, Garber, A., Baeres, F. M. M., Thomsen, H. & Pratley, R. E., Apr 2016, In: Endocrine Practice. 22, 4, p. 406-411 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits
Gjesing, A. M. P., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Urhammer, S. A., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Teis Schjals, 2012, In: Diabetologia. 55, 5, p. 1338-1345 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status
Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of oral contraceptives and/or metformin on GLP-1 secretion and reactive hypoglycaemia in polycystic ovary syndrome
Glintborg, D., Mumm, H., Holst, Jens Juul & Andersen, M., May 2017, In: Endocrine Connections. 6, 4, p. 267-277 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice
Gobron, B., Bouvard, B., Vyavahare, S., Blom, L. V. V., Pedersen, K. K., Windeløv, Johanne Agerlin, Boer, G. A., Harada, N., Zhang, S., Shimazu-Kuwahara, S., Wice, B., Inagaki, N., Legrand, E., Flatt, P. R., Chappard, D., Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette, Irwin, N. & Mabilleau, G., 2020, In: Journal of Bone and Mineral Research. 35, 7, p. 1363-1374 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., Dec 2007, In: The Journal of clinical endocrinology and metabolism. 92, 12, p. 4678-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4678-4685 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide-evoked release of amylase from isolated acini of the rat parotid gland
Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, Steen Seier & Holst, Jens Juul, 26 May 1994, In: Regulatory Peptides. 51, 3, p. 237-54 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidergic control of amylase secretion from the rat parotid gland
Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, S. S. & Holst, Jens Juul, 1994, In: Regulatory Peptides. 51, p. 237-254Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of sodium butyrate supplementation in milk replacer and starter diet on rumen development in calves
Gorka, P., Kowalski, Z. M., Pietrzak, P., Kotunia, A., Kiljanczyk, R., Flaga, J., Holst, Jens Juul, Guilloteau, P. & Zabielski, R., 2009, In: Journal of Physiology and Pharmacology. 60 Suppl 3, p. 47-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, B., Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-1310 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract
Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., Aug 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract
Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-937 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets
Goudoever, V., Stoll, B., Hartmann, B., Holst, Jens Juul, Reeds, P. J. & Burrin, D. G., 2001, In: J Nutr.. 131, p. 729-732Research output: Contribution to journal › Journal article › Research › peer-review
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TRPV1: A Potential Therapeutic Target in Type 2 Diabetes and Comorbidities?
Gram, D. X., Holst, Jens Juul & Szallasi, A., Nov 2017, In: Trends in Molecular Medicine. 23, 11, p. 1002-1013 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects
Greenfield, J. R., Farooqi, I. S., Keogh, J. M., Henning, E., Habib, A. M., Blackwood, A., Reimann, F., Holst, Jens Juul & Gribble, F. M., 2008, In: American Journal of Clinical Nutrition. 89, 1, p. 106-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Case report: Somatostatin producing teratoma, causing rapidly alternating extreme hyperglycemia and hypoglycemia, and ovarian somatostatinoma
Gregersen, G., Holst, Jens Juul, Trankjaer, A., Stadil, F. & Mogensen, A. M., 2002, In: Metabolism. 51, 9, p. 1180-1183 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-hyperglycemi effects of stevioside in type 2 diabetic subjects
Gregersen, S., Jeppesen, P. B., Holst, Jens Juul & Hermansen, K., 2004, In: Metabolism. 53, p. 73-76Research output: Contribution to journal › Journal article › Research › peer-review
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Antihyperglycemic effects of stevioside in type 2 diabetic subjects
Gregersen, S., Jeppesen, P. B., Holst, Jens Juul & Hermansen, K., Jan 2004, In: Metabolism. 53, 1, p. 73-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling
Gromada, J., Bokvist, K., Ding, W. G., Holst, Jens Juul, Nielsen, Jens Høiriis & Rorsman, P., 1998, In: Diabetes. 47, 1, p. 57-65 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats
Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031Research output: Contribution to journal › Journal article › Research › peer-review
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Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice
Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism
Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers
Grøndahl, M. F., Bagger, J. I., Lund, A., Faurschou, A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2018, In: Diabetes Care. 41, 6, p. 1260-1267Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon Clearance is Preserved in Type 2 Diabetes
Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity
Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets
Guan, X., Stoll, B., Lu, X., Tappenden, K., Holst, Jens Juul, Hartmann, B. & Burrin, D. G., 2003, In: Today in Medicine. Gastroenterology. 125, p. 136-147Research output: Contribution to journal › Journal article › Research
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GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow
Guan, X. F., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S. Y., Zhang, G. C., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D. L., Nichols, B. L. & Burrin, D. G., 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 150-164 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1
Guan, X., Stoll, B., Lu, X., Tappenden, K. A., Holst, Jens Juul, Hartmann, Bolette & Burrin, D. G., Jul 2003, In: Gastroenterology. 125, 1, p. 136-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow
Guan, X., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S., Zhang, G., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D., Hadsell, D. L., Nichols, B. L. & Burrin, D. G., Jan 2006, In: Gastroenterology. 130, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?
Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Are SADI-S and BPD/DS bariatric procedures identical twins or distant relatives? – A case report
Guimarães, M., Pereira, A. M., Pereira, S. S., Almeida, R., Lobato, C. B., Hartmann, Bolette, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Obesity Research and Clinical Practice. 17, 2, p. 166-170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass
Guimarães, M., Rodrigues, P., Pereira, S. S., Nora, M., Gonçalves, G., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Holst, Jens Juul & Monteiro, M. P., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-5 5 p., 150049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery
Guldstrand, M., Ahrén, B., Näslund, E., Holst, Jens Juul & Adamson, U., 2009, In: Diabetes, Obesity and Metabolism. 11, 11, p. 1027-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk
Gunnerud, U., Holst, Jens Juul, Östman, E. & Björck, I., 2012, In: Nutrition Journal. 11, p. 83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal
Gunnerud, U. J., Heinzle, C., Holst, Jens Juul, Östman, E. M. & Björck, I. M. E., 2012, In: P L o S One. 7, 9, p. e44731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcutaneous injection of glucagon-like insulintropic peptide reduces postprandial glycemia in non-insulin dependent diabetes
Gutniak, M. K., Linde, B., Holst, Jens Juul & Efendic, S., 1994, In: Diabetes Care. 17, p. 1039-1044Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic action of glucagon-like peptide- 1 related to administration relative to meal intake in subjects with type 2 diabetes
Gutniak, M. K., Svartberg, J., Hellstrom, P. M. & Holst, Jens Juul, 2001, In: J Intern Med. 250, p. 81-87Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic Effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus
Gutniak, M., Ørskov, Cathrine, Holst, Jens Juul, Ahrén, B. & Efendic, S., 1992, In: New England Journal of Medicine. 326, p. 1316-1322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin effect is an early sign of glucose dysmetabolism in nondiabetic patients with psoriasis
Gyldenløve, M., Vilsbøll, Tina, Zachariae, Claus, Holst, Jens Juul, Knop, Filip Krag & Skov, Lone, 11 Nov 2015, In: Journal of Internal Medicine. 278, 6, p. 660-70 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis
Gyldenløve, M., Vilsbøll, Tina, Holst, Jens Juul, Zachariae, Claus, Skov, L. & Knop, Filip Krag, Nov 2016, In: British Journal of Dermatology. 175, 5, p. 1085–1088Research output: Contribution to journal › Letter › Research › peer-review
- Published
Patients with psoriasis are insulin resistant
Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of method of delivery of sodium butyrate on rumen development in newborn calves
Górka, P., Kowalski, Z. M., Pietrzak, P., Kotunia, A., Jagusiak, W., Holst, Jens Juul, Guilloteau, P. & Zabielski, R., Nov 2011, In: Journal of Dairy Science. 94, 11, p. 5578-88 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1: on its way to clinical application
Göke, B., Göke, R., Holst, Jens Juul & Ørskov, C., 1994, In: Digestion. 54, p. 339-340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Gastrin‐Releasing Peptide in Vagal Control of Gastrin Secretion
Holst, Jens Juul, KNUHTSEN, S., Ørskov, Cathrine, SKAK‐NIELSEN, T., Poulsen, Steen Seier & NIELSEN, O. V., 1 Jan 1988, In: Annals of the New York Academy of Sciences. 547, 1, p. 514-515 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals
Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, Jens Juul, Baaré, W. F. C., Højgaard, Liselotte, Almdal, T. & Knudsen, G. M., 8 Apr 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-5889 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon
Haderslev, Kent Valentin, Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In: Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term administration of Glucagon-like peptide-2. Effects on bone mass density and markers of bone remodelling in short bowel patients with no colon
Haderslev, K. V., Jeppesen, P. B., Hartmann, B., Thulesen, J., Sørensen, H. A., Graff, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul, Staun, M. & Mortensen, P. B., 2002, In: Scandinavian Journal of Gastroenterology. vol. 37, p. 392-398Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition
Haedersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, p. S312-S312.Research output: Contribution to conference › Poster › Research
- Published
Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes
Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, Jens, Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion
Hagemann, D., Holst, Jens Juul, Gethmann, A., Banasch, M., Schmidt, W. E. & Meier, J. J., 2007, In: Regulatory Peptides. 143, 1-3, p. 64-68 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion
Hagemann, D., Holst, Jens Juul, Gethmann, A., Banasch, M., Schmidt, W. E. & Meier, J. J., 4 Oct 2007, In: Regulatory Peptides. 143, 1-3, p. 64-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure
Halbirk, M., Nørrelund, H., Møller, N., Holst, Jens Juul, Schmitz, O., Nielsen, B. R. R., Nielsen-Kudsk, J. E., Nielsen, S. S., Nielsen, T. T., Eiskjaer, H., Bøtker, H. E. & Wiggers, H., 1 Mar 2010, In: American Journal of Physiology: Heart and Circulatory Physiology. 298, 3, p. H1096-H1102Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
Halden, T. A. S., Egeland, E. J., Åsberg, A., Hartmann, A., Midtvedt, K., Khiabani, H. Z., Holst, Jens Juul, Knop, Filip Krag, Hornum, Mads, Feldt-Rasmussen, Bo & Jenssen, T., 23 Feb 2016, In: Diabetes Care. 39, p. 617-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans
Halim, M. A., Degerblad, M., Sundbom, M., Karlbom, U., Holst, Jens Juul, Webb, D. & Hellstrom, P. M., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 2, p. 575-585Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis
Han, X. X., Holst, Jens Juul & Galbo, Henrik, 2022, In: Journal of Personalized Medicine. 12, 5, 12 p., 837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.
Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Et nyopdaget fotopigment i retina, melanopsin, styrer hjernens biologiske ur.
Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 2002, In: Ugeskrift for læger. 164, 19, p. 2523Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?
Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs
Hansen, C. F., Thymann, Thomas, Andersen, A. D., Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Langhorn, L., Jelsing, J. & Sangild, Per Torp, 28 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 8, p. G550-560 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes
Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten, Andersen, H. U. & Dejgaard, T. F., 2019, In: Frontiers in Endocrinology. 10, 9 p., 242.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR119 as a fat sensor
Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of insulin resistance and obesity by stimulating GLP-1 release
Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010Research output: Patent
- Published
Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 1 Jul 2010, In: The Journal of clinical endocrinology and metabolism. 95, 7, p. 3309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists
Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, 2009, In: International Journal of Clinical Practice. 63, 8, p. 1154-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 447-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 4, p. 1363-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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