Holger Grohganz

Holger Grohganz

Associate Professor

ORCID: 0000-0002-0482-1397

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51 - 100 out of 124Page size: 50
  1. Published

    Coaxial electrospinning of polycaprolactone: A design of experiments approach

    Gürtler, Anna-Lena, Linseisen, I., Grohganz, Holger & Heinz, Andrea, 2024, In: European Polymer Journal. 208, 11 p., 112886.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The influence of moisture on the storage stability of co-amorphous systems

    Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Role of polymeric excipients in the stabilization of olanzapine when exposed to aqueous environments

    Paisana, M., Wahl, M., Pinto, J., Rades, Thomas (ed.), Grohganz, Holger (ed.) & Löbmann, Korbinian (ed.), 2015, In: Molecules. 20, 12, p. 22634-223282 200649.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Thermal investigation on hydrated co-amorphous systems of nicotinamide and prilocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 186, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling

    Wang, Y., Rades, Thomas & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 1, 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Towards a robust water content determination of freeze-dried samples by near-infrared spectroscopy

    Grohganz, Holger, Gildemyn, D., Skibsted, E., Fink, J. M. & Rantanen, Jukka, 2010, In: Analytica Chimica Acta. 676, p. 34-40

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis

    Chieng, N., Trnka, H., Bøtker, Johan Peter, Pikal, M., Rantanen, Jukka & Grohganz, Holger, 18 Jul 2013, In: International Journal of Pharmaceutics. 454, 1, p. 167-173 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, Thomas, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.

    Research output: Contribution to journal › Review › Research

  9. Published

    A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan

    Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The use of molecular descriptors in the development of co-amorphous formulations

    Meng-Lund, H. M. L., Korgaard, G. K., Jensen, K. B. T., Poso, A., Pantsar, T., Rades, Thomas, Rantanen, Jukka & Grohganz, Holger, 1 Jul 2018, In: European Journal of Pharmaceutical Sciences. 119, p. 31 38 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation

    Ruggiero, M. T., Krynski, M., Kissi, E. O., Sibik, J., Markl, D., Tan, N. Y., Arslanov, D., van der Zande, W., Redlich, B., Korter, T. M., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas, Elliott, S. R. & Zeitler, J. A., 2017, In: Physical chemistry chemical physics : PCCP. 19, 44, p. 30039-30047

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

    Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Compaction Behavior of Co-Amorphous Systems

    Sørensen, C. M., Rantanen, Jukka & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 3, 12 p., 858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17

    Research output: Contribution to journal › Journal article › Communication

  16. Published

    Preparation and characterization of spray-dried co-amorphous drug-amino acid salts

    Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Near-infrared (NIR) spectroscopy – a versatile tool for pharmaceutical research and production

    Grohganz, Holger, 2011, In: European Pharmaceutical Review. 16, 2, p. 57-60

    Research output: Contribution to journal › Journal article › Communication

  18. Published

    Ordnung muss (nicht) sein

    Löbmann, Korbinian, Jensen, K. B. T., Grohganz, Holger & Rades, Thomas, 2012, In: Lægemiddelforskning. 2012, p. 34-36

    Research output: Contribution to journal › Journal article › Communication

  19. Published

    Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying

    Craye, G., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., 2015, In: Molecules. 20, 12, p. 21532-48 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Unintended and in situ amorphisation of pharmaceuticals

    Priemel, P. A., Grohganz, Holger & Rades, Thomas, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 126-32 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Theoretical Considerations in Developing Amorphous Solid Dispersions

    Laitinen, R., Priemel, P. A., Surwase, S., Graeser, K., Strachan, C. J., Grohganz, Holger & Rades, Thomas, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 35-90 56 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions

    Löbmann, Korbinian, Laitinen, R., Strachan, C., Rades, Thomas & Grohganz, Holger, 1 Jan 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

    Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies

    Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.

    Research output: Contribution to journal › Review › Research

  25. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    In situ amorphisation of indomethacin with Eudragit® E during dissolution

    Priemel, P. A., Laitinen, R., Grohganz, Holger, Rades, Thomas & Strachan, C. J., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt B, p. 1259-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine

    Kasten, G., Nouri, K., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Nov 2017, In: International Journal of Pharmaceutics. 533, 1, p. 138-144 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability

    Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems

    Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The interplay between trehalose and dextran as spray drying precursors for cationic liposomes

    Lutta, A., Knopp, Matthias Manne, Tollemeto, M., Pedersen, Gabriel Kristian, Schmidt, S. T., Grohganz, Holger & Hagner Nielsen, L., 2024, In: International Journal of Pharmaceutics. 652, 10 p., 123798.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Exploring the chemical space for freeze-drying excipients

    Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Development and in vitro evaluation of a liposome based implant formulation for the decapeptide cetrorelix

    Grohganz, Holger, Tho, I. & Brandl, M., 2005, In: European Journal of Pharmaceutics and Biopharmaceutics. 59, 3, p. 439-448

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures

    Priemel, P. A., Laitinen, R., Barthold, S., Grohganz, Holger, Lehto, V., Rades, Thomas & Strachan, C. J., 18 Nov 2013, In: International Journal of Pharmaceutics. 456, 2, p. 301-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    INFLUENCE OF THE COOLING RATE AND THE BLEND RATIO ON THE PHYSICAL STABILTIY OF CO-AMORPHOUS NAPROXEN/INDOMETHACIN

    Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 13 Oct 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 109, p. 140-148 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin

    Beyer, A., Radi, L., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., Jul 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 104, p. 72-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

    Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids

    Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Supersaturating drug delivery systems: The potential of co-amorphous drug formulations

    Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Priemel, P., Strachan, C. J. & Rades, Thomas, 30 Oct 2017, In: International Journal of Pharmaceutics. 532, 1, p. 1-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems

    Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

    Di, Rong, Grohganz, Holger & Rades, Thomas, 2024, In: Pharmaceutics. 16, 15 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Salt hydrates as a source to form co-amorphous systems when prepared in the absence of water: Hydrogen bond analysis

    Deng, Y., Liu, S., Jiang, Y., Grohganz, Holger & Rades, Thomas, 2024, In: Chemical Engineering Science. 296, 120232.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Controlling production process: incorporating analytical methods

    Grohganz, Holger & Rantanen, Jukka, 2008, In: Pharma focus Asia. 8, p. 82-83

    Research output: Contribution to journal › Journal article › Communication

  45. Published

    Role of excipients in the quantification of water in lyophilised mixtures using NIR spectroscopy

    Grohganz, Holger, Fonteyne, M., Skibsted, E., Falck, T., Palmqvist, B. & Rantanen, Jukka, 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, p. 901-907

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Rapid solid-state analysis of freeze-dried protein formulations using NIR and raman spectroscopies

    Grohganz, Holger, Gildemyn, D., Skibsted, E., Flink, J. M. & Rantanen, Jukka, 2011, In: Journal of Pharmaceutical Sciences. 100, 7

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Near-Infrared Imaging for High-Throughput Screening of Moisture-Induced Changes in Freeze-Dried Formulations

    Trnka, H., Palou, A., Panouillot, P. E., Kauppinen, A., Toiviainen, M., Grohganz, Holger, Alcalà, M., Juuti, M., Ketolainen, J. & Rantanen, Jukka, 24 Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 9, p. 2839–2846 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The impact of surface- and nano-crystallisation on the detected amorphous content and the dissolution behaviour of amorphous indomethacin

    Priemel, P. A., Grohganz, Holger, Gordon, K. C., Rades, Thomas & Strachan, C., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 82, 1, p. 187-193

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The influence of lysozyme on mannitol polymorphism in freeze-dried and spray-dried formulations depends on the selection of the drying process

    Grohganz, Holger, Lee, Y., Rantanen, Jukka & Yang, Mingshi, 15 Apr 2013, In: International Journal of Pharmaceutics. 447, 1-2, p. 224-30 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Recent advances in co-amorphous drug formulations

    Dengale, S. J., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 May 2016, In: Advanced Drug Delivery Reviews. 100, p. 116-125 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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