Thomas Werge
Clinical Professor
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Genetic Variants Associated with Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study
Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O., 2019, In: JAMA Psychiatry. 76, 9, p. 924-932 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Anorexia Nervosa Genetics Initiative, A. N. G. I., Aug 2019, In: Nature Genetics. 51, 8, p. 1207-1214Research output: Contribution to journal › Letter › Research › peer-review
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Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia
Gasse, C., Wimberley, T., Wang, Y., Mors, O., Børglum, A., Als, T. D., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M. & Horsdal, H. T., 2019, In: Schizophrenia Research. 212, p. 79-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, , 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., Rajagopal, V. M., Als, T. D., T. Nguyen, H., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Domenici, E., Gamazon, E. R., Purcell, S., CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group & 15 others, , 2019, In: Nature Genetics. 51, p. 659-674Research output: Contribution to journal › Journal article › Research › peer-review
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Migraine polygenic risk score associates with efficacy of migraine-specific drugs
Kogelman, L. J. A., Esserlind, A-L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Hansen, T. F., Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, K., Brunak, S. & 73 others, , 2019, In: Neurology: Genetics. 5, 6, 12 p., e364.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions
Giovanoli, S., Werge, Thomas, Mortensen, P. B., Didriksen, M. & Meyer, U., 2019, In: Neuropsychopharmacology. 44, 4, p. 703-710 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of common genetic risk variants for autism spectrum disorder
Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, A. S. D. W. G. O. T. P. G. C., Mar 2019, In: Nature Genetics. 51, 3, p. 431-444Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study
Choi, K. W., Chen, C. Y., Stein, M. B., Klimentidis, Y. C., Wang, M. J., Koenen, K. C., Smoller, J. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F. & 31 others, , 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, , 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158Research output: Contribution to journal › Journal article › Research › peer-review
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Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Nature Communications. 10, 1, 18 p., 2548.Research output: Contribution to journal › Journal article › Research › peer-review
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BIOLOGICAL PREDICTORS OF PSYCHIATRIC TRAJECTORIES IN A DANISH POPULATION COHORT OF INDIVIDUALS WITH SCHIZOPHRENIA
Krebs, M., Themudo, G. E., Benros, Michael Eriksen, Werge, Thomas & Thompson, W., 2019, In: European Neuropsychopharmacology. 29, S5, p. S260-S260 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genome-wide association study identifies 30 loci associated with bipolar disorder
eQTLGen Consortium, E. C., May 2019, In: Nature Genetics. 51, 5, p. 793-803Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical association to FKBP5 rs1360780 in patients with depression
Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia, Werge, Thomas & Jørgensen, M. B., 2019, In: Psychiatric Genetics. 29, 6, p. 220-225 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population
Nissen, J., Trabjerg, B., Pedersen, M. G., Banasik, K., Pedersen, O. B., Sørensen, E., Nielsen, K. R., Erikstrup, C., Petersen, M. S., Paarup, H. M., Bruun-Rasmussen, P., Westergaard, D., Hansen, T. F., Pedersen, C. B., Werge, T., Torrey, F., Hjalgrim, H., Mortensen, P. B., Yolken, R., Brunak, S. & 2 others, , Oct 2019, In: Psychoneuroendocrinology. 108, p. 150-154Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders
Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., Nyegaard, M., Grove, J., Musliner, K. L., Ingstrup, K. G., Johannsen, B. M. W., Mægbæk, M. L., Wang, Y., Nordentoft, M., Mors, O., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B., Munk-Olsen, T. & 1 others, , 11 Nov 2019, In: Translational Psychiatry. 9, 1, 13 p., 288.Research output: Contribution to journal › Journal article › Research › peer-review
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Roadmap for a precision-medicine initiative in the Nordic region
Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 others, , 2019, In: Nature Genetics. 51, p. 924-930Research output: Contribution to journal › Comment/debate › Research
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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593
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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340
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published