Holger Grohganz

Holger Grohganz

Associate Professor


  1. Published

    Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation

    Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

    Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Development of a screening method for co-amorphous formulations of drugs and amino acids

    Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Formation mechanism of coamorphous drug−amino acid mixtures

    Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect

    Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., Oct 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 150-160 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

    Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin

    Doreth, M., Löbmann, Korbinian, Priemel, P., Grohganz, Holger, Taylor, R., Holm, R., Lopez de Diego, H. & Rades, Thomas, Jan 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122, p. 62-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

    Christensen, J. R., Meng-Lund, H., Grohganz, Holger, Poso, A., Laitinen, T., Korhonen, O., Jørgensen, Lene & Pajander, J., 1 May 2017, In: European Journal of Pharmaceutical Sciences. 102, p. 188-195 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Formation of mannitol hemihydrate in freeze-dried protein formulations-A design of experiment approach

    Larsen, H. M. L., Trnka, H. & Grohganz, Holger, 2 Jan 2014, In: International Journal of Pharmaceutics. 460, 1-2, p. 45-52 8 p.

    Research output: Contribution to journalJournal articleResearch

  11. Published

    Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan

    Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Preparation of Co-Amorphous Levofloxacin Systems for Pulmonary Application

    Gabelmann, A., Lehr, C. M. & Grohganz, Holger, 2023, In: Pharmaceutics. 15, 6, 15 p., 1574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocaine

    Xu, X., Rades, Thomas & Grohganz, Holger, 2024, In: International Journal of Pharmaceutics. 651, 7 p., 123807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions

    Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

    Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Whey proteins as stabilizers in amorphous solid dispersions

    Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Quantification of various phosphatidylcholines in liposomes by enzymatic assay

    Grohganz, Holger, Ziroli, V., Massing, U. & Brandl, M., 2003, In: AAPS PharmSciTech. 4, 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Quality by design approach in the optimization of the spray-drying process

    Baldinger, A., Clerdent, L., Rantanen, Jukka, Yang, Mingshi & Grohganz, Holger, 2012, In: Pharmaceutical Development and Technology. 17, 4, p. 389-397

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Refining stability and dissolution rate of amorphous drug formulations

    Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling

    Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica

    Monsuur, F., Choudhari, Y., Reddy, U., McCarthy, W., Sadek, I., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Sep 2016, In: International Journal of Pharmaceutics. 511, 2, p. 1135-1136

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

    Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Interaction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): A novel approach for stability assessment of oral drug carriers

    Bohsen, M. S., Tychsen, S. T., Kadhim, A. A. H., Grohganz, Holger, Treusch, A. H. & Brandl, M., 2023, In: European Journal of Pharmaceutical Sciences. 182, 10 p., 106384.

    Research output: Contribution to journalJournal articleResearchpeer-review

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