Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., Jul 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Determinants of glycemic charges in normoglycemic individuals

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, T., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetes. Suppl. 1, p. A659-A659 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor

    Murphy, R., Tura, A., Clark, P. M., Holst, Jens Juul, Mari, A. & Hattersley, A. T., 2008, In: Diabetologia. 52, 1, p. 154-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K., Schmidt, W. E., Schmitz, F. & Meier, J. J., Oct 2008, In: The Journal of clinical endocrinology and metabolism. 93, 10, p. 3995-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, E. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, Jens Juul, Fuller, P. J. & Bines, J. E., Jan 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The physiology and pharmacology of incretins in type 2 diabetes mellitus

    Holst, Jens Juul, 2008, In: Diabetes, Obesity and Metabolism. 10, Suppl. 3, p. 14-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects

    Enç, F. Y., Ones, T., Akin, H. L., Dede, F., Turoglu, H. T., Ulfer, G., Bekiroglu, N., Haklar, G., Rehfeld, Jens Frederik, Holst, Jens Juul, Ulusoy, N. B. & Imeryüz, N., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 296, 3, p. G482-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., Aug 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

    de Heer, J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, Dec 2008, In: Diabetologia. 51, 12, p. 2263-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Enteral nutrients potentiate the intestinotrophic action of glucagon-like peptide-2 in association with increased insulin-like growth factor-I responses in rats.

    Liu, X., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. p. 295:R1794-1802

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The Relationship between Glucagon-Like Peptide 2 and Feeding Intolerance in Preterm Infants.

    Ozer, E. A., Holst, Jens Juul, Duman, N., Kumral, A. & Ozkan, H., 2008, In: Journal of Tropical Pediatrics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Meal-induced compositional changes in blood and saliva in persons with bulimia nervosa

    Dynesen, A. W., Jensen, A. B., Astrup, A., Petersson, B., Holst, Jens Juul & Nauntofte, B., 2008, In: American Journal of Clinical Nutrition. 87, 1, p. 12-22 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, B., Wallace, L., Wright, J. & Sigalet, D. L., 2008, In: Pediatrics. 121, 1, p. E180-E186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast

    Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Bjorck, I. M., 2008, In: Journal of Nutrition. 138, 4, p. 732-739 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Glucagon-like peptide-1 inhibits blood-brain glucose transfer in humans

    Lerche, S., Brock, B., Rungby, J., Bøtker, H. E., Møller, N., Rodell, A., Bibby, B. M., Holst, Jens Juul, Schmitz, O. & Gjedde, Albert, 2008, In: Diabetes. 57, 2, p. 325-31 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans

    Pedersen-Bjergaard, Ulrik, Thomsen, Carsten Eckhart, Høgenhaven, H., Smed, A., Kjaer, T. W., Holst, Jens Juul, Dela, Flemming, Hilsted, Linda, Frandsen, E., Pramming, S. & Thorsteinsson, B., 2008, In: Journal of the Renin-Angiotensin-Aldosterone System. 9, 1, p. 37-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects

    Greenfield, J. R., Farooqi, I. S., Keogh, J. M., Henning, E., Habib, A. M., Blackwood, A., Reimann, F., Holst, Jens Juul & Gribble, F. M., 2008, In: American Journal of Clinical Nutrition. 89, 1, p. 106-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome

    Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes

    Müssig, K., Oncü, A., Lindauer, P., Heininger, A., Aebert, H., Unertl, K., Ziemer, G., Häring, H., Holst, Jens Juul & Gallwitz, B., 1 Sep 2008, In: American Journal of Cardiology. 102, 5, p. 646-7 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake

    Sørensen, L. B., Cueto, H. T., Andersen, M. T., Bitz, C., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 5, p. 1163-1169 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv : tidsskrift om ernæring. 1, p. 4-8 5 p.

    Research output: Contribution to journalJournal articleCommunication

  30. Published

    Glucagon-like peptide-1, glucose homeostasis and diabetes.

    Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Plasma glucagon-like peptide 1 and peptide YY levels are not altered in symptomatic fructose-sorbitol malabsorption.

    Valeur, J., Øines, E., Morken, M. H., Holst, Jens Juul & Berstad, A., 2008, In: Scandinavian Journal of Gastroenterology. 43, 10, p. 1212-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

    Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In: Frontiers in Bioscience. 13, p. 1780-94 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-937 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

    de, H. J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 12, p. 2263-2270 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes

    Mussig, K., Oncu, A., Lindauer, P., Heininger, A., Aebert, H., Unertl, K., Ziemer, G., Haring, H. U., Gallwitz, B. & Holst, Jens Juul, 2008, In: Journal of the American College of Cardiology. 102, 5, p. 646-647 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-1071 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome

    Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, B., Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-1310 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv. 1, 8

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Glucagon-like peptide-2 increases mesenteric blood flow in humans

    Bremholm, L., Hornum, Mads, Henriksen, B. M., Larsen, S. & Holst, Jens Juul, 2008, In: Scandinavian Journal of Gastroenterology. 44, 3, p. 314-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets

    Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients

    Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., May 2008, In: Diabetes. 57, 5, p. 1340-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monosaturated-fat, low-fat, and control diets

    Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: Challenges and feasibility

    Knop, F. K., Holst, Jens Juul & Vilsbøll, Tina, 2008, In: IDrugs. The Investigational Drugs Journal. 11, 7, p. 497-501 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Progression from normal glucose tolerance to impaired fasting glycaemia and impaired glucose tolerance: differential roles of insulin resistance and beta cell dysfunction

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Pedersen, O., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetologia. 51, Suppl. 1, p. S85-S86

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, Torben, Jørgensen, T. & Borch-Johnsen, K., 2008, In: Diabetes Care. 32, 3, p. 439-44 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Temporal changes in the intestinal growth promoting effects of glucagon-like peptide 2 following intestinal resection

    Kaji, T., Tanaka, H., Redstone, H., Wallace, L. E., Holst, Jens Juul & Sigalet, D. L., 2008, In: Journal of Surgical Research. 152, 2, p. 271-80 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats

    Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 30 Apr 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-65 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

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