Birgitte Holst

Birgitte Holst

Guest Researcher


Publication year:
All
1 - 25 out of 132Page size: 25
  1. Published

    Ghrelin-mediated improvements in the metabolic phenotype in the R6/2 mouse model of Huntington's disease

    Rudenko, Olga, Springer, C., Skov, Louise Julie, Madsen, A. N., Hasholt, Lis Frydenreich, Nørremølle, Anne & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7 (SI), 14 p., e12699.

    Research output: Contribution to journal › Conference article › Research › peer-review

  2. Published

    RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones

    Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.

    Research output: Contribution to journal › Conference article › Research › peer-review

  3. Published

    Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39

    Storjohann, L., Holst, Birgitte & Schwartz, Thue W., 2008, In: FEBS Letters. 582, 17, p. 2583-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor

    Holst, Birgitte, Lang, M., Brandt, E., Bach, Anders, Howard, A., Frimurer, T. M., Beck-Sickinger, A. & Schwartz, Thue W., 2006, In: Molecular Pharmacology. 70, 3, p. 936-46 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Stability, liposome interaction, and in vivo pharmacology of ghrelin in liposomal suspensions

    Møller, E. H., Holst, Birgitte, Nielsen, L. H., Pedersen, P. S. & Østergaard, Jesper, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 13-18

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    An enteroendocrine full package solution

    Schwartz, Thue W. & Holst, Birgitte, 2010, In: Cell Metabolism. 11, 6, p. 445-7 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist

    Lückmann, Michael, Holst, Birgitte, Schwartz, Thue W. & Frimurer, Thomas Michael, 2016, In: Molecular Informatics. 35, p. 19-24 6 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  8. Published

    GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery

    Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics

    Park, M., Sivertsen, B. B., Els-Heindl, S., Huber, T., Holst, Birgitte, Beck-Sickinger, A. G., Schwartz, Thue W. & Sakmar, T. P., 19 Nov 2015, In: Chemistry & Biology. 22, 11, p. 1431-1436 6 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  11. Published

    Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

    Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

    Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, Niels, Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Metabolic insights from a GHSR-A203E mutant mouse model

    Pedersen, Lola Julie Torz, Osborne-Lawrence, S., Rodriguez, J., He, Z., Paula Cornejo, M., Roman Mustafa, E., Jin, C., Petersen, N., Hedegaard, M. A., Nybo, Maja Lind, Martinez Damonte, V., Metzger, N. P., Mani, B. K., Williams, K. W., Raingo, J., Perello, M., Holst, Birgitte & Zigman, J. M., 2020, In: Molecular Metabolism. 39, 16 p., 101004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Anorexia and fat aversion induced by vertical sleeve gastrectomy is attenuated in neurotensin receptor 1–Deficient mice

    Ratner, C., Shin, J. H., Dwibedi, C., Tremaroli, V., Bjerregaard, Anette, Hartmann, Bolette, Bäckhed, F., Leinninger, G., Seeley, R. J. & Holst, Birgitte, 2021, In: Endocrinology. 162, 9, 12 p., bqab130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Biased Ghrelin Receptor Signaling and the Dopaminergic System as Potential Targets for Metabolic and Psychological Symptoms of Anorexia Nervosa

    Khelifa, M. S., Skov, Louise Julie & Holst, Birgitte, 2021, In: Frontiers in Endocrinology. 12, 13 p., 734547.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

    Backe, M. B., Jin, C., Andreone, L., Sankar, A., Agger, K., Helin, K., Madsen, A. N., Poulsen, Steen Seier, Bysani, M., Bacos, K., Ling, C., Javier Perone, M., Holst, Birgitte & Mandrup-Poulsen, Thomas, 2019, In: Journal of Diabetes Research. 2019, 15 p., 5451038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39

    Storjohann, L., Holst, Birgitte & Schwartz, Thue W., 2008, In: Biochemistry. 47, 35, p. 9198-207 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype

    Martini, L., Hastrup, H., Holst, Birgitte, Fraile-Ramos, A., Marsh, M. & Schwartz, Thue W., 2002, In: Molecular Pharmacology. 62, 1, p. 30-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis

    Holst, Birgitte, Hastrup, H., Raffetseder, U., Martini, L. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276, 23, p. 19793-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

    Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

    Holst, Birgitte, Nygaard, R., Hansen, L. V., Bach, Anders, Engelstoft, M. S., Petersen, P. S., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 6, p. 3973-85 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    ß-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia

    Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Wierup, N., Sundler, F., Holst, Birgitte & Schwartz, Thue W., 2011, In: International Journal of Endocrinology. 2011, p. 401258

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Beta-Cell Specific DMT1 KO Protects Islets from Cytokine Induced ROS and Apoptosis

    Hansen, J. B., Heller, S., Madsen, A. N., Holst, Birgitte, Tonnesen, M. F. & Mandrup-Poulsen, Thomas, 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  24. Published

    Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36

    Pedersen, S. L., Bhatia, V. K., Jurt, S., Paulsson, J. F., Pedersen, M. H., Jørgensen, R., Holst, Birgitte, Stamou, Dimitrios, Vrang, N., Zerbe, O. & Jensen, Knud Jørgen, 2012, In: Journal of Peptide Science. 18, 9, p. 579-587 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Acylation type determines ghrelin's effects on energy homeostasis in rodents

    Heppner, K., Chaudhary, N., Müller, T. D., Kirchner, H., Habegger, K. M., Ottaway, N., Smiley, D. L., Dimarchi, R., Hofmann, S. M., Woods, S. C., Sivertsen, B. B., Holst, Birgitte, Pfluger, P. T., Perez-Tilve, D. & Tschöp, M. H., Oct 2012, In: Contemporary Endocrinology. 153, 10, p. 4687-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 4 5 6 Next

ID: 9886