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Erik Richter

Erik Richter

Head of section, professor

  • Molecular Physiology

    Nørre Allé 51, 2200 København N, August Krogh Bygningen, Universitetsparken 13, 2100 Københav, Building: 2. sal

    Phone: +45 35 32 16 26Mobile: +45 28 75 16 26Fax: +45 35 32 16 00

Researcher ID: N-4189-2014

Primary research interests:

My primary research interests are regulation of muscle metabolism, particularly during and following exercise. This includes acute exercise and exercise training. Emphasis has been on regulation of glucose metabolism and muscle glucose uptake during exercise as well as regulation of insulin sensitivity following exercise and training. Besides the deep interest in revealing physiological and molecular mechanisms, the objectives are to delineate the molecular mechanisms behind the positive health effects of exercise. We know very well that basically all forms of exercise have positive health effects but we have little knowledge about the molecular mechanisms that are responsible for these effects. These mechanisms are important to understand as they might reveal novel drug candidate pathways that could be beneficial for prevention and treatment of metabolic and cardiovascular diseases.

320 publications on PubMed, >17500 citations and H-Index of 79 (Web of Science)

Personal Awards and Honours:

  • PI of the University of Copenhagen Excellence Grant 2016 with the title “Physical activity, Nutrition and Health” 2013-2017, 25,3 million dkk
  • Knight of the Order of Dannebrog 2013
  • Novo Nordisk Prize 2012
  • Honor Award Biochemistry of Exercise 2012
  • Citation Award American College of Sports and Medicine, 2005.

Selected recent publications:

  1. Sjoberg,KA, Frosig,C, Kjobsted,R, Sylow,L, Kleinert,M, Betik,AC, Shaw,CS, Kiens,B, Wojtaszewski,JF, Rattigan,S, Richter,EA, McConell,GK: Exercise Increases Human Skeletal Muscle Insulin Sensitivity Via Coordinated Increases in Microvascular Perfusion and Molecular Signaling. Diabetes 2017
  2. Sylow,L, Kleinert,M, Richter,EA, Jensen,TE: Exercise-stimulated glucose uptake - regulation and implications for glycaemic control. Nat Rev Endocrinol 13:133-148, 2017
  3. Kleinert,M, Parker,BL, Chaudhuri,R, Fazakerley,DJ, Serup,A, Thomas,KC, Krycer,JR, Sylow,L, Fritzen,AM, Hoffman,NJ, Jeppesen,J, Schjerling,P, Ruegg,MA, Kiens,B, James,DE, Richter,EA: mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3. Mol Metab 5:646-655, 2016
  4. Sylow,L, Nielsen,IL, Kleinert,M, Moller,LL, Ploug,T, Schjerling,P, Bilan,PJ, Klip,A, Jensen,TE, Richter,EA: Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice. J Physiol 594:4997-5008, 2016
  5. Hoffman,NJ, Parker,BL, Chaudhuri,R, Fisher-Wellman,KH, Kleinert,M, Humphrey,SJ, Yang,P, Holliday,M, Trefely,S, Fazakerley,DJ, Stockli,J, Burchfield,JG, Jensen,TE, Jothi,R, Kiens,B, Wojtaszewski,JF, Richter,EA, James,DE: Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates. Cell Metab 22:922-935, 2015

Teaching

  • Muscle metabolism
  • Physical activity
  • Health
  • Training
  • AMPK
  • Molekular signalling
  • Insulin sensitivity
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