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Lars Olsen

Lars Olsen

Associate Professor

Introductory remarks on publicationslist

See also Google Scholar


  1. 2018
  2. Accepted/In press

    7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. / Goffin, Eric; Drapier, Thomas; Larsen, Anja Probst; Geubelle, Pierre; Ptak, Christopher P; Laulumaa, Saara; Rovinskaja, Karoline; Gilissen, Julie; Tullio, Pascal de; Olsen, Lars; Frydenvang, Karla; Pirotte, Bernard; Hanson, Julien; Oswald, Robert E; Kastrup, Jette Sandholm; Francotte, Pierre.

    In: Journal of medicinal chemistry, 2018.

    Research output: Research - peer-reviewJournal article

  3. Published

    Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. / Jones, Sarah E; Olsen, Lars; Gajhede, Michael.

    In: Biochemistry, 2018.

    Research output: Research - peer-reviewJournal article

  4. 2017
  5. Published

    Dissecting the Cytochrome P450 1A2- and 3A4-Mediated Metabolism of Aflatoxin B1 in Ligand and Protein Contributions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Chemistry: A European Journal, Vol. 23, No. 12, 24.02.2017, p. 2884-2893.

    Research output: Research - peer-reviewJournal article

  6. Published

    Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions. / Bonomo, Silvia; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of chemical information and modeling, Vol. 57, No. 5, 22.05.2017, p. 1123-1133.

    Research output: Research - peer-reviewJournal article

  7. Published

    Structure-Based Design of a New Scaffold for Cell-Penetrating Peptidic Inhibitors of the Histone Demethylase PHF8. / Dorosz, Jerzy; Olsen, Lars; Seger, Signe Teuber; Steinhauer, Cornelia; Bouras, Giorgos; Helgstrand, Charlotte; Wiuf, Anders; Gajhede, Michael.

    In: ChemBioChem, Vol. 18, No. 14, 18.07.2017, p. 1369-1375.

    Research output: Research - peer-reviewJournal article

  8. Published

    Prediction of pKa values for druglike molecules using semiempirical quantum chemical methods. / Jensen, Jan Halborg; Swain, Christopher J; Olsen, Lars.

    In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, Vol. 121, No. 3, 2017, p. 699-707.

    Research output: Research - peer-reviewJournal article

  9. Published

    Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors. / Larsen, Morten; Hansen, Cecilie Hurup; Rasmussen, Tobias B.; Styrishave, Bjarne; Olsen, Lars; Jørgensen, Flemming Steen.

    In: Chemical Communications, Vol. 53, No. 3118, 3118, 28.02.2017.

    Research output: Research - peer-reviewJournal article

  10. Published

    Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH. / Nielsen, Line Marie; Holm, Niels Bjerre; Leth-Petersen, Sebastian; Kristensen, Jesper Langgaard; Olsen, Lars; Linnet, Kristian.

    In: Drug testing and analysis, Vol. 9, No. 5, 2017, p. 671–679.

    Research output: Research - peer-reviewJournal article

  11. Published

    The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region. / Tapken, Daniel; Steffensen, Thomas Bielefeldt; Leth, Rasmus; Kristensen, Lise Baadsgaard; Gerbola, Alexander; Gajhede, Michael; Jørgensen, Flemming Steen; Olsen, Lars; Kastrup, Jette Sandholm.

    In: Scientific Reports, Vol. 7, 46145, 07.04.2017.

    Research output: Research - peer-reviewJournal article

  12. Published

    The CYP79A1 catalyzed conversion of tyrosine to (E)-p-hydroxyphenylacetaldoxime unravelled using an improved method for homology modeling. / Vazquez Albacete, Dario; Montefiori, Marco; Kol, Stefan; Motawie, Mohammed Saddik; Møller, Birger Lindberg; Olsen, Lars; Nørholm, Morten H.H.

    In: Phytochemistry, Vol. 135, 2017, p. 8-17.

    Research output: Research - peer-reviewJournal article

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