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Thomas Rades

Thomas Rades

Professor

  • Pharmaceutical Design and Drug Delivery

    13, Building: 13-7-709

    2100 København Ø

    Phone: +45 35 33 60 32

Professional Affiliations/Memberships

  • APS Academy of Pharmaceutical Sciences (Member since 2007)
  • APSA, Australasian Pharmaceutical Science Association (Member since 2000, Member of the Executive Committee, 2002 -2005) • APV, International Association for Pharmaceutical Technology (Member since 1992)
  • CRS, Controlled Release Society (Member since 1996, Member of the Management Team of the Education Committee, 2003 - 2005; World-wide strategy leader for resource compilation, 2003 – 2005; Member of the Board of  Scientific Advisors, 2005-2007)
  •  CRS-NZ, New Zealand Chapter of the Controlled Release Society (Vice President, 2002 – 2004, President, 2004 -2008)
  • CRS-UKI, United Kingdom and Ireland Chapter of the Controlled Release Society (Member since 2007)
  • PhG, German Pharmaceutical Society (Member since 1992)
  • EAPB, European Association of Pharma Biotechnology (Founding member 2000)
  • NZIC, New Zealand Institute of Chemistry (Fellow since 2007)
  •  MNZ, Microscopy New Zealand (Member since 1996)
  •  OMSRS, Otago Medical Sciences Research Society (Member since 1996)
  •   PSSRC, Pharmaceutical Solid State Research Cluster (Director since 2006)
  •  RSNZ, Royal Society of New Zealand (Member since 2005)

Languages

  • German, fluently spoken and written
  • English, fluently spoken and written
  • French, basic knowledge spoken and written

  Employment History

Present Position
Research Chair in Pharmaceutical Design and Drug Delivery, Copenhagen University, Denmark, 03/2012 –

 Employment History
Chair in Pharmaceutical Sciences, School of Pharmacy, University of Otago, Dunedin, New Zealand, 10/2003 – 3/2012.
Senior Lecturer in Pharmaceutical Sciences, School of Pharmacy, University of Otago, Dunedin, New Zealand, 8/1999 - 9/2003
Research Scientist, Pharm. Research: Preclinical Development and Formulation, F. Hoffmann-La Roche, Basel, Switzerland, 4/1998 – 7/1999
Lecturer in Pharmaceutical Sciences, School of Pharmacy, University of Otago, Dunedin, New Zealand 1/1996 - 3/1998
Scientific Assistant, Technical University of Braunschweig, Department of Pharmaceutical Technology, Germany, 1/1995 - 12/1995
Scientific Employee, University of Marburg and Technical University of Braunschweig, Departments of Pharmaceutical Technology, Germany, 3/1990 - 12/1994

 Other Relevant Experience

Experience Working in an Overseas Country
Pharmacist, Nordsee-Apotheke & Nordsee Laboratorium, Ulmen-Apotheke, Hamburg, Germany, 5/1989 - 2/1990
Pre-registration Pharmacist, Nordsee-Apotheke & Nordsee Laboratorium, Hamburg, Germany, 4/1988 - 5/1989

 International Collaboration

Germany, Prof. Rolf Daniels, Technical University of Braunschweig, Department of Pharmaceutical Technology. Treatment of xerostomia using emulsion formulations, 1999 – 2003. Australia, Dr Christine Feinle, Prof Michael Horowitz, Royal Adelaide Hospital, Department of Medicine. The role of fat digestion in the development of dyspeptic symptoms in humans, 2000 – present.
United Kingdom, Prof. Sir Michael Pepper, Cavendish Laboratory, Cambridge. Vibrational spectroscopy of pharmaceuticals, 2003 – present.
Finland, A/Prof Vesa-Pekka, Department of Physics, University of Turku. Physico-chemical characterisation of mesoporous systems for drug release, 2005 – 2006.
Australia, Dr Ben Boyd, Victorian College of Pharmacy. Cubosomes and hexasomes as vaccine delivery systems, 2005 – present.
Australia, A/Prof Clive Prestige, University of South Australia, Ian Wark Research Institute. Physico-chemical and biopharmaceutical investigations of novel drug delivery systems for oral administration of lipophilic drugs, 2005 – present.
Denmark, Prof. Jukka Rantanen, University of Copenhagen, Faculty of Pharmaceutical Sciences, Department of Pharmaceutics and Analytical Chemistry, Copenhagen. Investigations into the amorphous state of drugs prepared by different techniques, 2005 – present.
France, Prof. Juergen Siepmann, College of Pharmacy, Université de Lille, Lille. Physicochemical characterisation of polymer films containing amorphous drugs, 2006 – present.
Germany, Prof. Peter Kleinebudde, Institute for Pharmaceutical Technology and Biopharmaceutics, Heinrich Heine University of Düsseldorf,  Analysis of coated tablets using TPS technology, 2006 – present.
United Kingdom, Dr Axel Zeitl, Department of Chemical Engineering, University of Cambridge, Imaging techniques for pharmaceuticals, 2006 – present.
Denmark, A/Prof. Anette Muellertz, University of Copenhagen, Faculty of Pharmaceutical Sciences, Department of Pharmaceutics and Analytical Chemistry, Copenhagen. Investigations into lipid formulations upon lipase induced precipitation, 2009 – present.  

 Research Activities

Research Expertise
Research interests are in formulation and drug delivery and physical characterisation of the solid and liquid crystalline state of matter. The research in both areas aims to improve drug therapy through appropriate formulation of medicines and to increase our understanding of the physico-chemical properties of drugs and medicines. It combines physical, chemical, and biological sciences and technology to optimally formulate drugs for human and veterinary uses. Specific research interests are: (1) Colloidal delivery systems for bioactives. (2) The solid state of drugs and dosage forms.

Experience in Applied R & D (consultancies, patents, contract research)
  • Consultancy: Pharmaceutical Research: Preclinical Development & Formulation Division, F. Hoffmann-La Roche, Basel, Switzerland, August 1999 – present
  • Consultancy: Member of the Board of Scientific Advisors, Phosphagenics, Melbourne, VIC, Australia, February 2007 – present
    Patent: Ho, L; Shen, YC; Taday, PF; Rades T: Analysis apparatus and method. UK Application Number: 0701646.2, Publication Number: GB2446026 (A8) (2008)
  • Patent: Taday, PF; Shen, YC; Ho, L; Rades T: A pharmaceutical analysis method and apparatus.  UK Application Number: 0712397.9, Publication Number: GB2446166 (A8) (2008)
  • Patent: Ho, L; Shen, YC; Taday, PF; Rades T: Analysis apparatus and method. International Application Number: PCT/GB208/00293, International Publication Number: WO2008/093067 A1 (2008)
  • Patent: Lee C, Rawle C, Strachan C, Rades T, Manson P, Payne C: Method and apparatus for performing a second order non-linear optical measurement on a sample. NZ Patent App. No: 537184 (2004) 
  • Patent: Feinle, C, Fried, M, Lengsfeld H, Rades T: Pharmaceutical composition and method for treatment of dyspepsia US Patent 6,534,539 (2003)
    Patent: Feinle, C, Fried, M, Lengsfeld H, Rades T: Use of lipase inhibitors European Patent EP 00117088.5 (2000)
  • Patent: Hadvary P, Lengsfeld H, Rades T, DeSmidt PC, Steffen H, Tardio J: Pharmaceutical compositions containing lipase inhibitors European Patent EP 99118180.1 (1999)
    Patent: Alex, R; Gerhards, J; Krämer-Pittrof, I; Oeschger, R; Rades, T: Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses US Patent 6,352,717 (1999)

  • Patent: Alex, R; Gerhards, J; Krämer-Pittrof, I; Oeschger, R; Rades, T: Process for the manufacture of liquid filled capsules. European Patent EP 98121831.6 (1998)
    Contract Research: Physico-chemical investigations on lactose (Lactose New Zealand, Hawera, New Zealand, February 2002 - 2005)
    Contract Research: Physico-chemical investigations on progesterone (InterAG, Hamilton, New Zealand, May 2002 - 2004)
    Contract Research: Stability of modification I of ranitidine-HCl (Dolorgiet Pharmaceuticals, St. Augustin, Germany, 1996 - 1998)
    Contract Research: Transmission electron microscopy investigations of liquid and semi-solid systems (several German Pharmaceutical companies, 1994 - 1995)

  Center/Consortia involvements:

  • IMI EU consortium: Biopharmaceutical Tools for Oral Drug Delivery (OrBiTo) (10 big Pharma companies, 10 European universities and 2 SMEs). €10.6 mio, 2012-2017; €0.75 mio at UCPH. Role: Task Leader.
  • Villum Kann Rasmussen Centre of Excellence “NanoMechanical Sensors” (Namec) in collaboration with DTU Nanotech. 28 mio DKK, 2009-14; 6 mio DKK at UCPH. Role: Task Leader.

 Research Grants

  • 2014  F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Co-administration of lipid DDS and API suspensions. SFr 80,000.
  • 2013  Phospholipid Research Center, Heidelberg (with Anette Müllertz, University of Copenagen): Elucidating the use of lyso-phospholipids in oral self-nanoemulsifying drug delivery systems. €75.000.
  • 2013  Lundbeckfonden, Development of co-amorphous drug-dipeptide formulations 110,000 DKK.
  • 2012   Lundbeckfonden (with Andrew Bond, University of Southern Denmark), Molecular-level understanding of co-amorphous pharmaceutical solids. DKK1,282,000 ($271,000).
  • 2011   PepsiCo Inc, New York, USA (industrial grant), Determination of the dissolution profile of salt samples. $45,000.
  • 2010   Bioneer A/S Copenhagen, Denmark (industrial grant), Production of Nanocrystals of atorvastatin calcium for use in fish oil products. $12,000.
  • 2010   PepsiCo Inc, New York, USA (industrial grant), Determination of the dissolution profile of salt samples. $45,000.
  • 2010   Douglas Pharmaceuticals, Auckland, New Zealand (industrial grant), Quantitative determination of amorphous content in acitretin samples. $11,000.
  • 2010   Boehringer-Ingelheim, Ingelheim, Germany (industrial grant), Characterisation of differently prepared pellets containing the drug BI14332CL. € 40,000 (approx. $75, 000).
  • 2009  Bioneer Farma, Copenhagen, Denmark (industrial grant), Determination of the Tg of tacrolimus and detection of crystalline tarcolimus. DKK 55,000 (approx. $15,400).
  • 2009  Laurenson Award, Preformulation of Puha for an antioxidant nutritional supplement. $11,990.
  • 2009  Boehringer Ingelheim, Bieberach, Germany (industrial grant), Development of analytical test methods and their application. € 6000 (approx. $12,600).
  • 2009 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Defining methods for the prediction of amorphous stability. SFr 80,000 (approx. $122,000).
  • 2009  NHMRC Project Grant No 565311 Effects of the fatty acid, lauric acid, on energy intake and gut motor and hormonal function in health and obesity. AUS $ 714,000 (approx. $ 780,000) (for three years, 2009-2011).
  • 2008  Otago Research Grant, Pre-clinical studies to improve the potency and practicality of a melanoma vaccine. $ 38,000.
  • 2008   Foundation for Research, Science and Technology NERF-Grant, Carbohydrate Nanotechnology - large, carbohydrate containing immuno-pharmaceuticals. $1.40 Mio. (for five years, 2008-2013).
  • 2008 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Thermal analysis for the prediction of amorphous stability. SFr 105,000 (approx. $115,000).
  • 2008 Cadbury (industrial grant), Collation and analysis of analytical and physicochemical data.  $40, 389.
  • 2008 Cadbury (industrial grant), Characterisation of crumb samples. $44, 699.
  • 2008 Heidelberg Pharma, Ladenburg, Germany (industrial grant), Development of a SMEDDS formulation for fosalvudine tidoxil. $132, 000.
  • 2007 Bayer, Leverkusen, Germany (industrial grant), Release of Propoxur from flea collars. € 18,000 (approx. $33,000).
  • 2007 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Amorphous systems. SFr 112,200 (approx. $125,000).
  • 2007   Boehringer-Ingelheim, Ingelheim, Germany (industrial grant), Physico-chemical characterisation of different batches of pimobendan. € 5,000 (approx. $9, 500).
  • 2007   Heidelberg Pharma, Ladenburg, Germany (industrial grant), Physico-chemical characterisation of fosalvudine tidoxil. € 6,000 (approx. $11, 350).
  • 2007   Rohm and Haas Spring House, PA, U.S.A. (industrial grant), Characterization of resinates as amorphous solids. US$ 17,000 (approx. $24,427).
  • 2007  Laurenson Award, Bioactivity of insulin delivered orally in nanoparticles dispersed in biocompatible microemulsions to diabetic rats. $16,688.
  • 2007  Phosphagenics, Melbourne, Australia (industrial grant), Characterisation and optimisation of tocopheryl phosphate particles. $195,240. 
  • 2007  Otago Research Grant, The amorphous state of saquinavir. $ 40,459.
  • 2006 Douglas Pharmaceuticals, Auckland, New Zealand (industrial grant), Stability of donepezil polymorphs. $5,000.
  • 2006  NZPERF Grant, Deeper understanding of drug manufacturing through process analytical technologies. $8,000.
  • 2006 GlaxoSmithKline Australia, Victoria, Australia (industrial grant), Investigation into amorphous product stability prediction. $51,420 (for three years).
  • 2006 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Physico-chemical investigations on APIs. SFr 150,000 (approx. $185,000).
  • 2006 Douglas Pharmaceuticals, Auckland, New Zealand (industrial grant), Characterisation and quantification of donepezil polymorphs. $21,401.
  • 2006  Technology New Zealand, Technology in Industry Fellowship (TIF), Prediction of tablet quality & API-lactose interaction using spectroscopic techniques. $158,000 (for three years).
  • 2005 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Physico-chemical investigations on APIs. SFr 100,000 (approx. $117,000).
  • 2005 Douglas Pharmaceuticals, Auckland, New Zealand (industrial grant), Quantification of drug polymorphism in solid dosage forms. $21,000.
  • 2005 Bayer, Leverkusen, Germany (industrial grant), Raman-spectroscopic investigations for the quantification of amorphous material in suspensions. €18,000 (approx. $33,000).
  • 2005 Douglas Pharmaceuticals, Auckland, New Zealand (industrial grant), Physico-chemical investigation of drug polymorphism. $18,000.
  • 2004 Otago Research Committee, Contestable theme funding, Purchase of a confocal Raman microscope. $50 000.
  • 2004  Easy Life Management Pty Ltd, Adelaide, Australia (industrial grant), Development and characterisation of oral formulations containing lauric acid. $25,000.
  • 2004  Laurenson Award, Immunostimulatory lipid implants for the delivery of cancer vaccines. $10,048.
  • 2004  Otago Research Grant, Using second harmonic generation to quantify polymorphism and crystallinity of pharmaceuticals. $ 31,084.
  • 2004  School of Pharmacy Research Grant, Preparation of modified nanoparticulate systems as vaccine delivery system. $ 16,000.
  • 2004  NZPERF Grant, New methods to analyse solid drugs & dosage forms. $8,000.
  • 2004 University of Adelaide Faculty of Health Sciences Research Development Award, Effects of the fatty acid, lauric acid, on energy intake and gastrointestinal motor and hormonal function. $Aus 9,000 (approx. $10,000). TR is a joint principle investigator with Dr C Feinle, University of Adelaide.
  • 2004  Royal Adelaide Hospital Research Committee Project Grant, Preliminary studies to evaluate the satiating potency of the free fatty acid, lauric acid, in healthy subjects. $Aus 18,000 (approx. $20,250). TR is a joint principle investigator with Dr C Feinle, University of Adelaide.
  •  2003  Foundation for Research, Science and Technology NERF-Grant, Carbohydrate nanotechnology. TR is Objective Leader of Objective 2 "ISCOMs" ($ 399.000 p.a. for five years) of this research theme.
  • 2003 Bayer, Leverkusen, Germany (industrial grant), Physico-chemical investigations on a suspension formulation. € 15,000 (approx. $30,000).
  • 2003 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Physico-chemical investigations on solids. SFr 100,000 (approx. $130,000).
  • 2003 NZPERF Grant, Formulation of colloidal carriers for proteins using methods that could be used in a hospital pharmacy, $9,300.
  • 2003 Committee for the Advancement of Learning and Teaching, Computer-aided learning package for principal components analysis, $7,971. TR is a joint principle investigator with A/Prof Keith Gordon, University of Otago.
  •  2002 Otago Research Grant, Novel spectroscopic techniques to investigate polymorphism and crystallinity of drugs, $21,300. TR is a joint principle investigator with A/Prof Keith Gordon, University of Otago.
  •  2001 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Physico-chemical investigations on new drugs, SFr 150,000 (approx. $200,000).
  • 2001 NZPERF Grant, Investigation of drug delivery into the skin using penetration enhancers. $3,600.
  • 2001 Otago Research Grant, Preparation of nanocapsules for protein/peptide delivery using a formulation reactor. $20,150.
  • 2001 New Zealand Dairy (industrial grant), Characterising pseudo-binary aqueous systems containing milk-derived phospholipids, $4,350. TR is a joint principle investigator with Dr Nigel Davies, University of Otago.
  • 2001 Neuronz (industrial grant), Physico-chemical characterisation of GPE, $16,000. TR is a joint principle investigator with Dr Nigel Davies, University of Otago.
  •  2000 NZPERF Grant, Investigation of drug delivery into the skin using penetration enhancers, $4,000. TR is a joint principle investigator with Dr Gordon Becket, University of Otago.
  • 2000 F. Hoffmann-La Roche, Basel, Switzerland (industrial grant), Physico-chemical investigations on lipid-water-systems, SFr 150,000 (approx. $200,000).
  • 2000 Otago Research Grant, Oral delivery of antigens using nanocapsules in microemulsions, $27,917. TR is a joint principle investigator with Dr Nigel Davies, University of Otago.
  • 1999 Otago Research Grant, Physico-chemical properties of sugar replacement compounds, $40,504. TR is a joint principle investigator with Dr Miang Lim, University of Otago.
  • 1999 NZPERF Grant, Investigation of the mechanism of action of penetration enhancers in drug delivery into and through the skin, $4,000. TR is a joint principle investigator with Dr Gordon Becket, University of Otago.
  • 1999 NZPERF Grant, Dispersions of nanocapsules in microemulsions, $6,385.
  •  1998 NZPERF Grant, Use of microemulsions in ocular drug delivery, $4,330. TR is a joint principle investigator with Dr Nigel Davies, University of Otago.
  • 1997 NZPERF Grant, Preparation and characterisation of immune stimulating complexes containing viral protein, $4,850. TR is a joint principle investigator with Dr Nigel Davies, University of Otago.
  • 1997 Otago Research Grant, Colloidal systems for delivery of bioactive antigens, $26,235.
  • 1997 Otago Research Grant, Student Scholarship, Colloidal systems for delivery of bioactive antigens, $24,000.
  •  1996 Formulation and Drug Delivery Group, Summer Scholarship, Investigations on the echogenic properties of suspensions. $ 3,000.
  • 1996 Otago Research Grant, Microemulsions and their use as ocular drug delivery systems. $14,000.
  • 1996 Lottery Science Research Grant, Thermal microscopy of drugs and drug delivery systems. $15,000.
  • 1996 Dolorgiet GmbH & Co. KG, Bonn, Germany (industrial grant), Stability of modification I of ranitidine-HCl. $12,000.
  • (2)  Please list below any research grant on which you are a named contributing researcher.
  • 2009  Lottery Health Research, Grant in aid; Equipment purchase essential for the advancement of biomedical research, $100,000). PI: Dr Dorothy Oorschot, University of Otago.
  • 2009  NZPERF Grant, Rapid detection of counterfeit and adulterated products using vibrational spectroscopy, $8,500). PI: Dr Clare Starchan, University of Otago.
  • 2006 Otago Research Grant, Development of sustained release colloidal vaccines,   $ 19,492. PI: Dr Sarah Hook, University of Otago.
  • 2005 Australian Research Council, ARC Discovery Grant, Physico-chemical and  administration of lipophilic drugs. $Aus 260,000 (approx. $ 283,000) for three years (Year 1: $Aus 100,000; Year 2: $Aus 80,000; Year 2: $Aus 80,000).  TR is a joint principle investigator with A/Prof CA Prestidge and Prof AM Evans, University of South Australia.
  • 2005 Otago Research Grant, Superantigen modified particulate vaccine delivery systems, $ 17,798. PI: Dr Sarah Hook, University of Otago.
  • 2005 NZPERF Grant, Investigation of drug stability in suspensions by Raman spectroscopy, $ 3,700 PI: Dr Dorothy Saville, University of Otago.
  • 2005 NZPERF Grant, Application of milling & spray drying techniques to optimise solid state properties, $ 7,300 PI: Dr Dorothy Saville, University of Otago.
  • 2003 NZPERF Grant, Using CpG modified cationic immune stimulating complexes to deliver peptide vaccines to dendritic cells, $ 6,391. PI: Dr Sarah Hook, University of Otago.
  • 2002 Genesis Oncology Trust, Use of ISCOMs as cancer vaccines, $ 22,608. PI: Dr Sarah Hook, University of Otago.
  • 2002 Otago Research Grant, Use of mannosylated liposomes in the delivery of antigens to the immune system, $ 25,000. PI: Dr Nigel Davies, University of Otago.
  • 2001 Otago Research Grant, Colloidal systems for sub- and trans-cutaneous antigen delivery, $ 24,600. PI: Dr Nigel Davies, University of Otago.
  • 2000 Otago Research Grant, Analysis of drugs using new spectroscopic techniques, $22,000. PI: Dr Keith Gordon, University of Otago.
  • 2000 Otago Research Grant, Improved delivery of antigens to dendritic cells using sugar-coated liposomes, $28,220. PI: Dr Nigel Davies, University of Otago.
  • 1997 Otago Research Grant, Application of neuro-fuzzy hybrid computing in pharmaceutical science, $28,818. PI: Prof Ian Tucker, University of Otago.
  • 1996 Lottery Health Research Grant, Receptor mediated antigen acquisition by dendritic cells, $83,160. PI: Dr Margaret Baird, University of Otago.
  • 1996 Lottery Health Research Grant, Particle sizing equipment, $50,000. PI: Prof Ian Tucker, University of Otago.  

 PhD – ongoing

  1. PhD ’Amorphous activation of drugs during administration. Maria Doreth, 2014 –
  2. PhD Oral delivery of Amphotericin B using lipids. Scheyla Daniela, 2014 -  [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (A/Prof A Müllertz)]
  3. PhD The use of lyso-phospholipids in  for SNEDDS and drug suspensions with SNEDDS. Thy Thuy Tran, 2014 -  [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (A/Prof A Müllertz)]
  4. PhD Understanding drug precipitation during digestion. Jamal Kahn, 2013 - ongoing [in collaboration with the Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia (Prof B Boyd)]
  5. PhD Solid-state transformations during pharmaceutical processes. Andreas Beyer, 2013 -  [in collaboration with the Department of Pharmacy, University of Hamburg, Germany (Prof K Leopold)]
  6. Studies on the tabletting of coated drug pellets with the goal of developing an optimized MUPS-Formulation (multiple unit pellet system). Anna Novikova, 2013 -  [in collaboration with the Department of Pharmacy, University of Hamburg, Germany (Prof K Leopold)]
  7. PhD Tableting of pressure sensitive drugs with a focus on pancreatic enzymes. Marten Klukkert, 2013 -  [in collaboration with the Department of Pharmacy, University of Hamburg, Germany (Prof K Leopold)]
  8. PhD Amorphous formulation in preclinical development. Matthias Knopp, 2013 – ongoing [in collaboration with the Faculty of Pharmaceutical Sciences, University of Mainz, Germany (Prof P Langguth) and H. Lundbeck AS, Valby, Denmark (Dr Rene Holm)]
  9. PhD Physiologically relevant physic-chemical characterization tools – a way to predict drug absorption? Cecilie Maria Madsen, 2013 – on-going [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (A/Prof A Müllertz)]
  10. PhD Elucidation of the role of mixed micelles in absorption of poorly water soluble drugs, Maria Høtoft Michaelsen, 2013 – on-going
  11. PhD Towards predictive models for lipid-based drug delivery systems, Philip Jonas Sassene, 2013 – on-going [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (A/Prof A Müllertz)]
  12. PhD Stabilising amorphous drugs by forming co-amorphous drug-excipient combinations, Katrine Brigitte Tarp Jensen, 2012 – on-going
  13. PhD Simulation of gastric precipitation, Linda Grøn Jensen, 2012 – on-going
  14. PhD Single-shot hydrogel vaccines – increasing success and decreasing costs of global immunization campaigns Silke Neumann, 2010 – on-going Thesis is currently submitted.
  15. PhD Stabilisation of protein drugs in phospholipid delivery systems, Paulina Guzman, 2010 – on-going Thesis is currently written up.

 PhD – completed

  • PhD Formulation of antioxidant phytochemicals form Sonchos species, Ellen Ou, 2010 – 2014
  • PhD Solid state conversions on the surface, Petra Priemel, 2010 - 2013 [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (Dr H Grohganz) and the University of Helsinki, Finland (Dr C Strachan)]
  •  PhD  The use of process analytical technology in the formulation of co-amorphous formulations, Korbinian Loebmann, 2010 – 2013 [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (Dr H Grohganz)] THIS THESIS HAS BEEN PLACED ON THE HEALTH SCIENCE DIVISIONAL LIST OF EXCEPTIONAL PHD THESES
  •  PhD Drug formulations for microcontainers, Line Hagner Nielsen, 2009 – 2013 [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (A/Prof A Müllertz)]
  •  PhD Tabletting of physico-chemically instable APIs, Sönke Rehder, 2010 – 2013 [in collaboration with the Department of Pharmacy, University of Hamburg, Germany (Prof C Leopold)].
  •  PhD Enhanced dissolution testing, Johan Bøtker, 2010 – 2013 [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (Prof J Rantanen)].
  •  PhD Optimizing the ideal carrier-drug composition for solid dispersions with fast screening analytical methods, Jian Xiong Wu, 2010 – 2013 [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (Prof J Rantanen)].
  •  PhD Terahertz pulsed spectroscopy and imaging on pharmaceutical formulations, Miriam Haaser, 2009 – 2013 [in collaboration with TeraView, Cambridge, UK (M Pepper)]
  •  PhD  Formulation and immunological characterization of novel carbohydrate containing immuno-pharmaceuticals, Madlen Hubert, 2009 – 2013.
  •  PhD  Transdermal delivery of peptide vaccines, Teerawan Rattanapak, 2009 – 2013.
  •  PhD Optimisation and in-vitro/in vivo correlation of lipid-based drug delivery systems, Nicky Thomas, 2009 – 2012 [in collaboration with the Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark (A/Prof A Müllertz)] THIS THESIS HAS BEEN PLACED ON THE HEALTH SCIENCE DIVISIONAL LIST OF EXCEPTIONAL PHD THESES  After his PhD NT started work as a postdoctoral fellow at the Department of Pharmacy at the University of Copenhagen, Denmark
  •  PhD Development of Tabernaemontana divarivata extract loaded transdermal delivery system by microemulsion for cholinesterase inhibitory activities,  Wantida Chaiyana, 2009 – 2012 [in collaboration with the Faculty of Pharmaceutical Sciences, Chiang Mai University, Thailand (A/Prof S Okonogi)]  After her PhD WC started work as a lecturer at Chiang Mai University, Thailand
  •  PhD Polymer matrix formation in tablets prepared by direct compression, Chompak Pirayavaraporn, 2008 – 2012.
  •  PhD Influence of preparative techniques on the structure, stability and dissolution of amorphous drugs, Pranav Karmwar, 2008 – 2011.  After his PhD PK started work as a postdoctoral fellow at Boehringer Ingelheim, Bieberach, Germany
  •  PhD Milling behaviour of drugs, Ulrike Zimper, 2007 – 2011.  After her PhD UZ started work as a process development engineer in Cape Town, South Africa.
  •  PhD Development and evaluation of chitosan-magnesium aluminum silicate nano-composite films for pharmaceutical use, Wanwisa Khunawattanakul, 2009 – 2011.
  •  PhD Preparation and physico-chemical characterisation of self gelling liquid crystalline vaccine delivery systems on the basis of biocompatible microemulsion templates, Rinku Singh, 2007 – 2011.  After his PhD RS started work as an analytical quality control person at a chemical company in Auckland, New Zealand.
  •  PhD Pharmaceutical nanotechnology for biocontrol of the brushtail possum in New Zealand, Alexandra Kafka, 2006 – 2010.  After her PhD AK started work as a research scientist at Coriolis PharmaService GmBH in Munich, Germany.
  •  PhD Physicochemical characterisation of the matrix tablet microstructure, Lipika Chatterjee, 2006 – 2010.  After her PhD AC started work as a research assistant in the School of Pharmacy, University of Otago, Dunedin, New Zealand.
  • PhD On the stability prediction of amorphous drugs, Kirsten Graeser, 2006 – 2009 [in collaboration with GSK, Harlow, UK]  After her PhD KG started work as a group leader at F. Hoffmann-La Roche in Basel, Switzerland.   PhD Chitosan hydrogels containing particulate antigen as vaccine delivery systems, Sarah Gordon, 2006 – 2009.  After her PhD SG started work as a postdoctoral research fellow at the Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark
  • PhD Understanding film coating quality. From non-destructive film coating quality analysis to dissolution prediction using terahertz pulsed imaging, Louise Ho, 2006 – 2009 [in collaboration with TeraView, Cambridge, UK].  After her PhD LH started work as a postdoctoral research fellow at the Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, Australia  THIS THESIS HAS BEEN PLACED ON THE HEALTH SCIENCE DIVISIONAL LIST OF EXCEPTIONAL PHD THESES
  • PhD On the importance of drug-polymer interactions in controlled drug delivery systems, Bianca Glaessl, 2006 – 2009 [in collaboration with Lille University, Lille, France]  After her PhD BG started work as a research scientist at Merck in Darmstadt, Germany.
  • PhD Skin delivery using nanotechnology, Kristina Ferderber, 2005 – 2009 [in collaboration with Pliva, Croatia]  After her PhD KF started work as a research scientist at Pliva in Zagreb, Croatia.
  • PhD  Cubosomes - colloidal delivery systems for cancer vaccines, Shakila Rizwan, 2005 – 2009 [in collaboration with Monash University, Melbourne, Australia]  After her PhD SR started work as a postdoctoral research fellow at the Department of Anatomy and Structural Biology, University of Otago, Dunedin, New Zealand
  • PhD Physicochemical properties of amorphous systems, Norman Chieng, 2005 – 2008.  After his PhD NC started work as a research fellow on an industrial contract with Roche and the University of Otago and then went on to a postdoctoral  position at the University of Connecticut, Ct. USA.
  •  PhD Comparison of different preparative and analytic techniques to study amorphous pharmaceutical materials, Andrea Heinz, 2005 - 2008.  After her PhD AH started work as a pharmacist at a retail pharmacy in Germany.
  •  PhD Quil-A containing lipid implants as vaccine delivery systems, Julia Myschik, 2005 – 2008.  After her PhD JM started work as a post doctoral fellow at the Department of Pharmaceutical Technology, Ludwig-Maximilian University Munich, Germany.
  • PhD New insights into the amorphous state and related solid state transformations, Marja Savolainen, 2005 – 2008.  After her PhD MS started work as a post doctoral fellow at the School of Pharmacy, University of Copenhagen, Denmark.
  • PhD Preparation and physico-chemical characterisation of nanoparticles from microemulsion templates, Anja Graf, 2005 – 2008.  After her PhD AG started work as a lecturer at the New Zealand National School of Pharmacy, University of Otago, Dunedin, New Zealand. 
  •  PhD  Quality of medicines in South Africa: Understanding the impact of consumers’ and providers’ perspectives on procurement and use behaviour, Aarti Patel, 2004 – 2009.  After her PhD AP continued to work as a lecturer in the School of Pharmacy, University of Otago, Dunedin, New Zealand.
  • PhD Characterisation of protein - phospholipid interactions in vaccine delivery systems, Ruedeeporn Tantipolphan, 2004 – 2007  After her PhD RT started work as a post doctoral fellow at the Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands.     PhD Liposome stability in frozen systems, Lee Fong Siow, 2004 – 2007.  After her PhD LFS started work as lecturer in food sciences at the Sunway Campus of Monash University, Bandar Sunway, Malaysia.
  • PhD The use of Raman-spectroscopy for the quantification of different solid forms of drugs in pharmaceutical suspensions. Fang Tian, 2004 – 2006  After her PhD FT has started work as a post doctoral fellow at the Pharmaceutical University Copenhagen, Denmark.
  • PhD Investigation of Terahertz spectroscopy - use in pharmaceutical systems, Axel Zeitler, 2004 – 2006  [in collaboration with TeraView, Cambridge, UK]  After his PhD AZ has started work as a post doctoral fellow at the Department of Chemical Engineering at Cambridge University, UK.  THIS THESIS HAS BEEN PLACED ON THE HEALTH SCIENCE DIVISIONAL LIST OF EXCEPTIONAL PHD THESES
  • PhD Influence of microemulsion microstructure and surfactant type on the efficiency of skin permeation of hydrophobic and hydrophilic drugs, Prapaporn Boonme, 2004 – 2006  After her PhD PB has continued work as a lecturer at the Department of Pharmaceutical Technology, Prince of Songkla University, Thailand.
  • PhD ISCOMs as delivery systems for antigens, Dirk Lendemans, 2003 – 2006  After his PhD DL has started work as a deputy head of a laboratory in the analytical development section of Merck & Co. KG in Darmstadt, Germany.
  • PhD Oral delivery of bioactive compounds to the common brushtail possum (Trichosurus vulpecula), Arlene McDowell, 2003 – 2005  After her PhD AMcD  has started work as a lecturer at the School of Pharmacy, University of Otago, Dunedin, NZ
  • PhD Spectroscopic investigation and quantitation of polymorphism and crystallinity of pharmaceutical compounds, Clare Strachan, 2002 – 2005  After her PhD CS  has started work as a postdoctoral research fellow at the Department of Pharmaceutical Technology, University of Helsinki, Finland
  • PhD Modified liposomes as adjuvants, Karen White, 2002 – 2005  After her PhD KW  has started work as a postdoctoral research fellow at the Victorian College of Pharmacy, Monash University, Melbourne, Australia
  • PhD Formulation and characterisation of nanoparticles from biocompatible microemulsions, Karen Krauel, 2001 – 2005  After her PhD KK  has started work as a postdoctoral research fellow at Boehringer-Ingelheim, Ingelheim, Germany
  • PhD Improving the immunogenicity of influenza subunit antigens through the use of antigen delivery systems and immune modulators, Jeremy Wales, 2001 – 2004  After his PhD JW  has started work as a postdoctoral research fellow at Imperial College in London, UK
  • PhD Investigation of the amorphous state of drugs and drug-PVP mixtures prepared by different solid dispersion techniques, James Patterson, 2001 – 2004 [in collaboration with GSK, Stevenage, UK]  After his PhD JP has started work as a senior research scientist at GlaxoSmithKline in Ware, UK.
  • PhD Investigation of the physico-chemical properties of sugars in frozen systems, Jens Liesebach, 2001 - 2003  After his PhD JL has started work as a research scientist at Zuegg Fruit Products in Berlin, Germany.
  • PhD ISCOMs and related colloidal particles prepared by the lipid film hydration method for antigen delivery, Patrick Demana, 2000 - 2004  After his PhD PD  has started work as a senior lecturer at the School of Pharmacy, Tshwane University of Technology, Pretoria, South Africa
  • PhD Investigation of the mechanism of action of penetration enhancers in drug delivery into and through the skin, Sarunyoo Songkro, 1999 - 2003  After her PhD SS has continued work as a lecturer at the Department of PharmaceuticalTechnology, Prince of Songkla University, Thailand.
  • PhD Pharmaceutical solid dispersions formed by co-precipitation, Gabriel Sertsou, 1999 - 2002 [in collaboration with GSK, Stevenage, UK]  After his PhD GS has started work as a senior research scientist at GlaxoSmithKline in Ware, UK after his PhD.
  • PhD Preparation, characterisation and cellular processing of antigen containing nanocapsules, Tasana Pitaksuteepong, 1999 - 2002  After her PhD TP has started work as an assistant professor at the Department of Pharmaceutical Technology, Naresuan University, Thailand.
  • PhD The use of amorphous compounds and solid-dispersions to enhanceoral bioavailability, Angus Forster, 1999 – 2001 [in collaboration with GSK, Stevenage, UK]  After his PhD AF has started work as a senior research scientist at GlaxoSmithKline in Stevenage, UK after his PhD.
  • PhD Nanoparticulate dispersions as oral drug delivery systems for peptides, Suchat Watnasirichaikul, 1997 - 2000  After his PhD SW has started work as research scientist at the Government Pharmaceutical Organisation, Bangkok, Thailand.
  • PhD Colloidal systems for the delivery of bioactive material to dendritic cells, Melissa Copland, 1997 - 2003  After her PhD MZ has started work as the owner of Queenstown Pharmacy, Queenstown, New Zealand.
  • PhD Water-in-oil microemulsions as vehicles for ocular drug delivery: formulation, physicochemical characterisation and evaluation, Raid Alany, 1996 - 2001  After his PhD RA has started work as a lecturer at the School of Pharmacy, University of Auckland, NZ.

   MPharm/MSc

  • MPharm Adding polymers to self-nanoemulsifying drug delivery systems (SNEDDS) containing poorly soluble drugs – Can supersaturation be induced during in vitro lipolysis? Charlotte Løf Henriksen, 2010 – 2011
  • MPharm The use of Raman-spectroscopy for the quantification of different polymorphic forms of drugs. Destari Pratiwi, 2000 - 2002. Degree awarded with DISTINCTION.
  • MPharm Stability of Modification I of Ranitidine-HCl, Vivian Wu, 1996 - 1998. Degree awarded with DISTINCTION.
  • MPharm Proliposomes as drug delivery systems, Siriporn Runglertkriangkrai, 1996 - 1997. Degree awarded with DISTINCTION.
  • MSc Shelf life of sugar confectionery with particular reference to sugar crystallization kinetics in a model marshmallow system, Yin Jia, 2003 - 2004
  • MSc The effects of composition on the glass transition and crystallisation rate of low calorie hard candies, Janet McFetridge, 2000 - 2001. Degree awarded with DISTINCTION.
  • MSc Characterisation of the physical properties of lactitol, Ben Lampen, 1999 - 2001. Degree awarded with DISTINCTION.

 Dipl.Pharm. (MPharm, Germany/Austria)

  • Dipl.Pharm. (Germany) Investigation of the influence of tableting and storage on the secondary structure of a protein, Maria Doreth, 2014.
  • Dipl.Pharm. (Austria) Development of silica coated liposomes for vaccine delivery, Sandra Prasch, 2010.
  • Dipl.Pharm. (Austria) Establishment of an in vitro lipolysis model, Sophie Wenger, 2010.
  • Dipl.Pharm. (Austria) Self-gelling microemulsions as nanoparticle templates – a novel approach for a depot drug delivery system, Elisabeth Ablinger, 2007. Degree awarded with DISTINCTION
  • Dipl.Pharm. (Germany) Entwicklung einer Methode zum Einbau von Ovalbumin in ISCOMs, Stephanie Könnings, 2001. Degree awarded with DISTINCTION
  • Dipl.Pharm. (Germany) Einfluss verschiedener Herstellungsparameter auf die Eigenschaften von Ethyl-2-cyanoacrylat-Nanokapseln, Karen Krauel, 2000 – 2001.
  • Dipl.Pharm. (Germany) Untersuchungen über die Inkorporierung von FITC-Ovalbumin in ISCOMs, Isabell Joachim, 2000 – 2001.

 PGCert (Pharmacy)

  • PG Cert Characterisation and imaging of three BI 14332 CL micropellet samples, May Mah, 2011
  • PG Cert Optimization of carbamazepine:PVP ratio in solid dispersions, Shan Pan, 2010
  • PG Cert Co-Crystal formation during a wet granulation process, Marten Klukkert, 2010
  • PG Cert Effect of nanonisation and amorphisation on dissolution behaviour of a BCS Class II drug, Himang Mujoo, 2010
  • PG Cert Crystallisation of nitrofurantoin from water – acetone mixtures, in the presence of polymers, Sebastian Kapp, 2010
  • PG Cert Physicochemical characterisation of naproxen-ranitidine hydrochloride binary system prepared by ball milling, Janine Tillmann, 2009
  • PG Cert  Preformulation of puha for an antioxidant nutritional supplement, Mirjam Stark, 2009
  • PG Cert  Preparation and characterization of lecithin based systems for transdermal delivery of peptides, Kathrin Radermacher, 2008
  • PG Cert Characterisation of a novel silica particle in chitosan gel formulation, Elena Teichmann, 2008
  • PG Cert Comparison of X-ray powder diffraction and Raman spectroscopy in quantifying ternary mixtures of ranitidine hydrochloride solid state forms, Soehnke Rehder, 2008
  • PG Cert Co-crystal formation of carbamazepine polymorphs (form 1 and 3) and dihydrate with nicotinamide prepared by ball milling, Madlen Hubert, 2008
  • PG Cert Liposomal formulations with tocopheryl phosphate as lipid components for transdermal drug delivery, Georg Pester, 2007
  • PG Cert Characterisation and in vitro release of ovalbumin from cubosomes produced via low viscosity precursors for vaccine delivery, Ann Kristin Boehnke, 2007
  • PG Cert Effect of the particle size and mechanical properties of the excipients on polymer matrix formation, Anne-Kathrin Baier, 2007
  • PG Cert Dehydration of carbamazepine dihydrate in the presences of polymers, Wolfram Lorenzen, 2007
  • PG Cert Characterisation and optimisation of tocopheryl phosphate particles, Svenja Steinbrinck, 2007
  • PG Cert Characterisation of resinates as amorphous solids, Anna Lueg, 2007
  • PG Cert Preparation and characterisation of insulin-loaded nanoparticles via microemulsion, Martin Graf, 2006
  • PG Cert Thermal analysis of carbamazepine, Nadine Tolle, 2006, submitted
  • PG Cert Formulation of a vaccine delivery system, Kathrin Boehm, 2006, submitted
  • PG Cert Pharmacopeial quality of medicines from South Africa and Samoa, Elke Huber, 2006, submitted
  • PG Cert Influence of different sustained release agents on the release of model antigen from an immunostimulatory lipid implant, Miriam Heger, 2006, submitted
  • PGCert Influence of polymorphic form, morphology and excipient interactions on the dissolution of carbamazepine compacts, Carolin Lang, 2006
  • PGCert Release of model antigen from Quil A containing solid lipid implants, Frederike Eberhardt, 2006
  • PGCert Development and characterization of lyotropic liquid crystalline nanoparticles produced via low viscosity precursors for vaccine delivery, Dirk Assmus, 2006
  • PG Cert Formulation and analysis of colloidal dispersions containing Quil-A, Anne Marie Egert, 2005
  • PGCert Formulation and characterisation of microemulsions, Sylvia Peters, 2005
  • PGCert Development of an oral drug delivery system for lauric acid, Annika Phillips, 2005
  • PGCert Characterisation of liposomes containing imiquimod, Nicky Thomas, 2005
  • PGCert Analysis and quantitation of the polymorphic form of leflunamide in tablets, Florian Matl, 2005
  • PGCert Formulation of lauric acid and triglycerides of lauric acid as an oral dosage form, Corinna Kronschnabel, 2005
  • PGCert Raman spectroscopic investigation for the quantification of amorphous material in suspension s of ampicillin trihydrate and oxacillin sodium in middle chain triglycerides, Johanna Kanzer, 2005
  • PGCert  Development of test methods to determine and quantify the polymorphic form of risperidone in tablets, Kirsten Graeser, 2005
  • PGCert Physico-chemical characterisation of pharmaceutical solids, Marc Kriesten, 2004
  • PGCert Factors influencing the formation of nanoparticles -a factorial study, Vanessa Bunjes, 2004
  • PGCert  Stability of insulin-loaded nanoparticles in enzyme solutions, Ulrike Jüse, 2004
  • PGCert Dissolution testing of amorphous solid dispersions, Peter Maisel, 2003 – 2004
  • PGCert Development of a method for the preparation of immune stimulating complexes (ISCOMs) utilizing synthetic saponin derivatives, Knut Hartmann, 2003 - 2004
  • PGCert Formulation of ISCOMs (immune-stimulating complexes) by ethanol injection, Julia Myschik, 2003 - 2004
  • PGCert Characterisation of water-free microemulsions, Anja Graf, 2003 - 2004
  • PGCert Immunological effects of incorporated Quil A in FITC-OVA-loaded nanoparticles, Silke Born, 2003 - 2004
  • PGCert Raman spectrosocopic investigations on the polymorphism of crystalline drugs in aqueous suspensions, Hendrik Stukenbrock, 2003
  • PGCert Influence of milling on the polymorphism of ranitidine hydrochloride, Ute Dunkel, 2003
  • PGCert Investigation of colloidal dispersions containing phosphatidylethanolamine and Quil A, Bianka Berger, 2003
  • PGCert Qualitative and quantitative analysis of the physical stability of the thermotropic mesophase of fenoprofen calcium by XRPD, DRIFTS and PCA, Karin Benten, 2003
  • PGCert Characterisation and quantification of polymorphs of enalapril maleate by HPLC, DRIFTS and XRPD, Ulrike Dahlke, 2002 -2003
  • PGCert Development of emulsions for intraduodenal administration, Cornelia Keck, 2002 -2003
  • PGCert A transmission electron microscopic study of ISCOMs and other colloidal structures prepared by the hydration-rehydration method, Uwe Vosgerau, 2002 -2003
  • PGCert Poly (alkyl cyanoacrylate) nanocapsules as delivery systems for hydrophilic drugs, Alexandra Kafka, 2001
  • PGCert Interfacial polymerisation of water-rich microemulsions containing cosurfactants, Sebastian Georgi, 2001
  • PGCert Polymerisation of water-rich microemulsions including the investigation of the entrapment of a hydrophilic model-drug, Sabine Rothmann, 2001  
  •  

 Distinctions

  • Honorary Doctorate, Åbo Akademie University, Turku, Finland, 2014
  • Eminent Fellow of the Academy of Pharmaceutical Sciences, UK, 2013
  • Appointed as Honorary Professor at the School of Pharmacy, University of Otago, Dunedin, NZ, 2013 –
  • Otago University PhD supervisor of the year (Top 10), Dunedin, New Zealand 2010
  • Appointed as Council Member of the Otago Institute, 2010 - 2012.
  • Named in the list of top 3 reviewers for the Journal of Liposome Research in 2009
  • Otago University PhD supervisor of the year (finalist), Dunedin, New Zealand 2009
  • 2009 “Best Paper Award” for best research paper published in Drug Development and Industrial Pharmacy: Melt Extrusion and Spray Drying of Carbamazepine and Dipyridamole with Polyvinylpyrrolidone/Vinyl Acetate Copolymers. James E. Patterson, Michael B. James, Angus H. Forster, Thomas Rades, 34:95–106, 2008
  • Appointed as Guest Professor at the Faculty of Pharmaceutical Sciences, Copenhagen University, Copenhagen, Denmark, 2009 - 2012
  • Otago University PhD supervisor of the year (finalist), Dunedin, New Zealand 2008
  • Named in the list of top reviewers for the Journal of Pharmaceutical Sciences for 2007
  • Inaugural Pfizer Lecturer in Pharmaceutical Technology, University of Connecticut, USA, 2007
  • Fellow of the New Zealand Institute of Chemistry, 2007
  • Fellow of St Margaret’s College, University of Otago, 2006
  • New Zealand Tertiary Teaching Excellence Award for Sustained Excellence, 2005
  • Otago University Award for Sustained Excellence in Tertiary Teaching, 2005
  • Appointed as Visiting Professor at the Department of Medicine at the University of Adelaide, Australia, 2004 -
  • Appointed as Guest Lecturer at the School of Pharmacy, Technical University of Braunschweig, Germany, 2001 - 2003
  • AGA Poster of Distinction, Annual AGA Meeting, DDW, Orlando, Florida (1999)
  • CDC Poster Award, 4th Expert Meeting on Colloidal Dug Carrier, Berlin, Germany (1999)
  • PhD awarded “summa cum laude” (1994)
  • APV Poster Prize, 38. Annual Congress of the Association of Pharmaceutical Technology, Regensburg, Germany (1992)

 

Publications

Books

1. Perrie Y, Rades T, Fasttrack: Pharmaceutics - Drug Delivery and Targeting, 1st Ed. (October 2009), Pharmaceutical Press, London, Chicago [ISBN: 978 0 85369 762 6], 2nd Ed. (June 2012), Pharmaceutical Press, London, Chicago [ISBN: 978 0 85711 059 6]

 

Book chapters

  1. Müller-Goymann C, Folger M, Rades T, Salben, Cremes, Gele, Pasten. Hagers Handbuch der Pharmazeutischen Praxis, 5th Ed. (Vol. 2) 1991; Nürnberg E and Surmann P (Eds.); Springer Verlag, Berlin, Heidelberg, New York; p 871 – 915 [ISBN: 3-5405-2459-2].
  2. Lee CJ, Strachan CJ, Rades T, Manson PJ, Nonlinear optics as a method for materials characterisation. Lasers and Electrooptics research at the cutting edge, 2006; Larkin SB (Ed.); Nova Scientific Publications, New York; p 63 – 122 [ISBN: 1-60021-194-1].
  3.  Saupe A, Rades T, Solid lipid nanoparticles. Nanocarrier Technologies - Frontiers of Nanotechnology, 2006; Mozafari MR (Ed.); Springer Verlag, Berlin, Heidelberg, New York; p 41-50 [ISBN: 1-4020-5040-2].
  4. Zeitler JA, Rades T, Taday PF, Pharmaceutical and security applications of terahertz spectroscopy. THz spectroscopy: Principles and Applications, 2007; Dexheimer SL (Ed.); Taylor and Francis, London;  [ISBN: 0849375258]
  5. Graf A, Krauel-Goellner K, Rades T, Poly(alkylcyanoacrylate) nanoparticles for drug delivery and vaccine development. Colloids in Drug Delivery, 2010; Fanun M (Ed.); Taylor and Francis/CRC Press, London; p 99 - 136 [ISBN: 9781439818251]
  6. im MH, Lampen B, Siow LF, Rades T, Physical changes in confectionary products caused by the availability of water, with a special focus on lactitol crystallization. Water properties in food, health pharmaceutical and biological systems, 2010; Reid DS, Sajjaanantakul T, Lillford PJ, Charoenrein S (Eds); Wiley-Blackwell; p 271 - 284 [ISBN: 9780813812731]
  7. Siow LF, Rades T, Lim MH, From water to ice: Investigation of the effect of ice crystal reduction on the stability of frozen large unilamellar vesicles. Water properties in food, health pharmaceutical and biological systems, 2010; Reid DS, Sajjaanantakul T, Lillford PJ, Charoenrein S (Eds); Wiley-Blackwell; p 551 - 562 [ISBN: 9780813812731]
  8. Rades T, Gordon K, Graeser K, Molecular Structure, Properties and States of Matter. Remington - The Science and Practice of Pharmacy, 22nd edition, 2012; Allen LV Jr (Ed); Pharmaceutical Press; p 541- 570 [ISBN: 978 0 85711 062 6]
  9. Rades T, Gordon K, Graeser K, Molecular Structure, Properties and States of Matter. Remington – Essentials of Pharmaceutics, 2012; Linda A Felton (Ed); Pharmaceutical Press; p 177- 207 [ISBN: 978 0 85711 105 0]
  10. Hook S, Rades T, Immune Stimulating Complexes (ISCOMs) and Quil-A Containing Particulate Formulations as Vaccine Delivery Systems. Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines (Immunomics Reviews:) 2013; Flower DR, Perrie Y (Eds); Springer; p 233 – 261 [ISBN-10: 1461450691, ISBN-13: 978-1461450696]  

 

Int. peer reviewed journal articles

  1. Rades T, Müller-Goymann CC, Structural investigations on the liquid crystalline phases of fenoprofen. Pharmaceutical and Pharmacological Letters 2: 131 - 134 (1992). COLLOIDAL SYSTEMS
  2. Hirsch R, Rades T, Grimm D, Langfermann I, Phasenvolumenbestimmung mit Integrationsokkular. Pharmazeutische Zeitung. 138: 2575 - 2580 (1993). COLLOIDAL SYSTEMS
  3. Rades T, Schütze W, Müller-Goymann CC, Interactions between gelatin and amphiphilic substances. Die Pharmazie 48: 425 - 432 (1993). COLLOIDAL SYSTEMS
  4. Rades T, Schütze W, Hirsch R, Müller-Goymann CC, Influence of amphiphilic substances on the coil-helix transformation of gelatin. Die Pharmazie 49: 294 - 295 (1994). COLLOIDAL SYSTEMS
  5. Hildebrand G, Kriwet K, Rades T, Müller-Goymann CC, Relationship between cytotoxic and physicochemical properties of some nonsteroidal anti-inflammatory drugs. Pharmaceutical and Pharmacological Letters. 3: 202 - 206 (1994). COLLOIDAL SYSTEMS
  6. Rades T, Müller-Goymann CC, Melting behaviour and thermotropic mesomorphism of fenoprofen salts. European Journal of Pharmaceutics and Biopharmaceutics 40: 277 - 282 (1994). SOLID STATE
  7. Rades T, Müller-Goymann, CC, Fenoprofen-Natrium, Flüssigkristalline Zustände. Deutsche Apotheker Zeitung 134: 1268 - 1272 (1994). SOLID STATE
  8. Rades T, Padmadisastra Y, Müller-Goymann CC, Thermal behaviour and solubility of fenoprofen calcium. Die Pharmazie 51: 846 - 851 (1996). SOLID STATE
  9. Rades T, Gerke A, Schütze W, Müller-Goymann CC, Characterization of a commercial liposome spray. Die Pharmazie 52: 44 - 50 (1997). COLLOIDAL SYSTEMS
  10. Rades T, Müller-Goymann CC, Electron- and light-microscopic investigation of defect structures in mesophases of pharmaceutical substances. Colloid and Polymer Science 275: 1169 - 1178 (1997). SOLID STATE
  11. Rades T, Müller-Goymann CC, Investigations on the micellisation behaviour of fenoprofen sodium. International Journal of Pharmaceutics 159: 215 - 222 (1997). COLLOIDAL SYSTEMS
  12. Rades T, Müller-Goymann C C, Interactions between fenoprofen-sodium and poly-(ethylene oxide). European Journal of Pharmaceutics and Biopharmaceutics 46: 51 - 59 (1998). COLLOIDAL SYSTEMS
  13.  Forster A, Gordon K, Schmierer D, Soper N, Wu V, Rades T, Characterisation of two polymorphic forms of ranitidine-HCl. Internet Journal of Vibrational Spectroscopy 2: 12 (1998). SOLID STATE
  14. . Ellin KE, Dietz HP, Wilson PD, Rades T, Coarse dispersed systems as ultrasound contrast media. Die Pharmazie 54: 195 - 199 (1999). COLLOIDAL SYSTEMS
  15.  Alany R, Agatonovic-Kustrin S, Rades T, Tucker IG, Use of artificial neural networks to predict quartenary phase systems from limited experimental data. Journal of Pharmaceutical and Biomedical Analysis 19: 443 - 452 (1999). COLLOIDAL SYSTEMS
  16.  Agatonovic-Kustrin S, Wu V, Rades T, Saville D, Tucker IG, Powder diffractometric assay of two polymorphic forms of ranitidine hydrochloride. International Journal of Pharmaceutics 184 (1): 107 - 114 (1999). SOLID STATE
  17. Sertsou G, Agatonovic-Kustrin S, Rades T, The use of DRIFTS to analyse binary mixtures of two polymorphic forms of ranitidine-HCl using only one specific peak. Internet Journal of Vibrational Spectroscopy 3 (5) 5 (1999). SOLID STATE
  18.  Alany R, Rades T, Agatonovic-Kustrin S, Davies NM, Tucker IG, Effects of alcohols and diols on the phase behaviour of quaternary systems. International Journal of Pharmaceutics 196: 141 - 145 (2000). COLLOIDAL SYSTEMS
  19. Copland MJ, Rades T, Davies NM, Hydration of lipid films with an aqueous solution of Quil A: A simple method for the preparation of immune-stimulating complexes. International Journal of Pharmaceutics 196: 135 - 139 (2000). COLLOIDAL SYSTEMS
  20. De Smidt PC, Rades T, Direct detection of 14C-labelled compounds into an oil phase by the fat scintillation proximity method. International Journal of Pharmaceutics 196: 187 - 191 (2000). COLOIDAL SYSTEMS
  21. Agatonovic-Kustrin S, Wu V, Rades T, Saville D, Tucker IG, Ranitidine hydrochloride x-ray assay using a neural network. Journal of Pharmaceutical and Biomedical Analysis 22 (6): 985 - 992 (2000). SOLID STATE
  22. Watnasirichaikul S, Davies NM, Rades T, Tucker IG, Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions. Pharmaceutical  Research 17 (6): 684 - 689 (2000). COLLOIDAL SYSTEMS
  23. Wu V, Rades T, Saville DJ, Stability of polymorphic forms of ranitidine hydrochloride. Die Pharmazie, 55 (7): 508 - 512 (2000). SOLID STATE
  24. Alany R, Davies NM, Tucker IG, Rades T, Characterising colloidal structures of pseudoternary phase diagrams formed by oil/water/amphiphile systems. Drug Development and Industrial Pharmacy 27 (1) 31 - 38 COLLOIDAL SYSTEMS
  25. Forster A, Hempenstall J, Rades T, Investigation of drug/polymer interaction in glass solutions prepared by melt extrusion. Internet Journal of Vibrational Spectroscopy [www.ijvs.com] 5, 2, 6 (2001). SOLID STATE
  26. Forster A, Hempenstall J, Rades T, Characterisation of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers. Journal of Pharmacy and Pharmacology 53: 303 - 315 (2001). SOLID STATE
  27. Feinle C, Rades T, Otto B, Fried M, Fat digestion modulates gastrointestinal sensations induced by gastric distension and duodenal lipids in humans. Gastroenterology 120: 1100 - 1107 (2001). COLLOIDAL SYSTEMS
  28. Agatonovic-Kustrin S, Rades T, Wu V, Saville D, Tucker IG, Determination of polymorphic forms of ranitidine-HCl by DRIFTS and XRPD. Journal of Pharmaceutical and Biomedical  Analysis 25 (5-6): 741 - 750 (2001). SOLID STATE
  29. Faas H, Schwizer W, Feinle C, Lengsfeld H, de Smidt PC, Boesiger P, Fried M, Rades T, Monitoring the intragastric distribution of a colloidal drug carrier model by magnetic resonance imaging. Pharmaceutical Research 18 (4): 460 - 466 (2001). COLLOIDAL SYSTEMS
  30. Lewisham K, Ferguson M, Rades T, Emulsions as oral moisturisers for the treatment of severe xerostomia. Die Pharmazie 56 (7): 591-592 (2001). COLLOIDAL SYSTEMS
  31. Forster A, Hempenstall J, Tucker IG, Rades T, Selection of excipients for melt extrusion with two poorly water -soluble drugs by solubility parameter calculation and thermal analysis. International Journal of Pharmaceutics 226: 147 - 161 (2001). SOLID STATE
  32. Forster A, Hempenstall J, Tucker IG, Rades T, The potential of small scale fusion experiments and the Gordon-Taylor equation to predict the suitability of drug/polymer blends for melt extrusion. Drug Development and Industrial Pharmacy 27: 549 - 560 (2001). SOLID STATE
  33. Faas H, Steingoetter A, Feinle C, Rades T, Lengsfeld H, Boesiger P, Fried M, Schwizer W, Effects of meal consistency and ingested fluid volume on the intragastric distribution of a drug model in humans - an MRI study. Alimentary Pharmacology and Therapeutics 16: 217 - 224 (2002). COLLOIDAL SYSTEMS
  34. Watnasirichaikul S, Rades T, Tucker IG, Davies NM, Effects of formulation variables on characteristics of poly (ethylcyanoacrylate) nanocapsules prepared from w/o microemulsions. International Journal of Pharmaceutics 235: 237 - 246 (2002). COLLOIDAL SYSTEMS
  35. Pitaksuteepong T, Davies NM, Tucker IG, Rades T, Factors influencing the entrapment of hydrophilic compounds in nanocapsules prepared by interfacial polymerisation of water-in-oil microemulsions. European Journal of Pharmaceutics and Biopharmaceutics 53: 335 - 342 (2002). COLLOIDAL SYSTEMS
  36. Watnasirichaikul S, Rades T, Tucker IG, Davies NM, In-vitro release and oral bioactivity of insulin in diabetic rats using nanocapsules dispersed in a biocompatible microemulsion. Journal of Pharmacy and Pharmacology 54: 473 - 480 (2002). COLLOIDAL SYSTEMS
  37. Könnings S, Copland MJ, Davies NM, Rades T, A method for the incorporation of ovalbumin into immune stimulating complexes (ISCOMs) prepared by the hydration method. International Journal of Pharmaceutics 241: 385 - 389 (2002). COLLOIDAL SYSTEMS
  38. Sertsou G, Butler J, Hempenstall J, Rades T, Solvent change co-precipitation with hydroxypropylmethylcellulose phthalate to improve dissolution characteristics of a poorly water-soluble drug Journal of Pharmacy and Pharmacology 54: 1041 - 1047 (2002). SOLID STATE
  39. Sertsou G, Butler J, Scott A, Hempenstall J, Rades T, Factors affecting incorporation of drug into solid solution with HPMCP during solvent change co-precipitation. International Journal of Pharmaceutics 245: 99 - 108 (2002). SOLID STATE
  40. Forster A, Rades T, Hempenstall J, Selection of suitable drug and excipient candidates for preparation of glass solutions by melt extrusion for immediate release oral formulations. Pharmaceutical Technology Europe 14: 27 - 37 (2002). SOLID STATE
  41. Patterson J, Bary A, Rades T, Physical stability and solubility of the thermotropic mesophase of fenoprofen calcium as pure drug and in a tablet formulation. International Journal of Pharmaceutics 247: 147 - 157 (2002). SOLID STATE
  42. Pratiwi D, Fawcett JP, Gordon KC, Rades T, Quantitative analysis of polymorphic mixtures of ranitidine hydrochloride by Raman spectroscopy and principal components analysis. European Journal of Pharmaceutics and Biopharmaceutics 54: 337 - 341 (2002). SOLID STATE
  43. Copland MJ, Baird MA, Rades T, McKenzie JL, Becker B, Reck F, Tyler P, Davies NM. Liposomal Delivery of Antigen to Human Dendritic Cells. Vaccine 21: 883 - 890 (2003). COLLOIDAL SYSTEMS
  44. Sertsou G, Butler J, Hempenstall J, Rades T, Physical stability and enthalpy relaxation of drug-hydroxypropyl methylcellulose phtalate solvent change co-precipitates. Journal of Pharmacy and Pharmacology 55: 35 - 41 (2003). SOLID STATE
  45. Songkro S, Becket G, Rades T, Investigation in newborn pig skin as an in vitro animal model for transdermal drug delivery. STP Pharma Sciences 13: 133 - 139 (2003). TRANSDERMAL DELIVERY
  46. Songkro S, Rades T, Becket G, The effects of p-menthane monoterpenes and related compounds on the percoutaneous absorption of propranolol hydrochloride across newborn pig skin. Part I: In vitro skin permeation and retention studies. STP Pharma Sciences 13: 349 - 357 (2003). TRANSDERMAL DELIVERY
  47. Liesebach J, Rades T, Lim M, Determination of the solute concentration of sugars in frozen systems near the maximal freeze concentrations. Thermochimica Acta 401: 159-168 (2003). SOLID STATE
  48. Forster A, Apperley D, Hempenstall J, Lancaster R, Rades T, Investigation of the physical stability of amorphous drug and drug/polymer melts using variable temperature solid state NMR. Die Pharmazie 58: 761-762 (2003). SOLID STATE
  49. Forster A, Hempenstall J, Rades T, Comparison of the Gordon-Taylor and Couchman-Karasz equations for prediction of the glass transition temperature of glass solutions of drug and polyvinylpyrrolidone prepared by melt extrusion. Die Pharmazie 58: 838-839 (2003). SOLID STATE
  50. Songkro S, Becket G, Rades T, The effects of p-menthane monoterpenes and related compounds on the percoutaneous absorption of propranolol hydrochloride across newborn pig skin. Part II: Infrared spectroscopic and thermal analytical investigations. STP Pharma Sciences 13: 397-404 (2003). TRANSDERMAL DELIVERY
  51.  Demana PH, Vosgerau U, Davies NM, Rades T, Pseudo ternary phase diagrams of aqueous systems of Quil A, cholesterol and phospholipid for immune stimulating complexes (ISCOMs). International Journal of Pharmaceutics 270: 229-239 (2004). COLLOIDAL SYSTEMS
  52. Liesebach J, Lim M, Rades T, Determination of the unfrozen matrix concentration of simple carbohydrate solutions and their mixtures using stepwise DSC. Thermochimica Acta 411: 43-51 (2004). SOLID STATE
  53. Strachan C, Pratiwi D, Gordon KC, Rades T, Quantitative analysis of polymorphic mixtures of carbamazepine by Raman spectroscopy and principal components analysis. Journal of Raman Spectroscopy 35: 347-352 (2004). SOLID STATE
  54. Pitaksuteepong T, Davies NM, Baird M, Rades T, Uptake of antigen encapsulated in polythylencyanoacrylate nanoparticles by D1-dendritic cells. Die Pharmazie 59: 134-142 (2004).  COLLOIDAL SYSTEMS
  55. Strachan CJ, Rades T, Newnham DA, Gordon KC, Pepper M, Taday PF, Using Terahertz Pulsed Spectroscopy to Study Crystallinity of Pharmaceutical Materials. Chemical Physics Letters 390: 20 - 24 (2004). SOLID STATE
  56. Demana PH, Davies NM, Berger B, Vosgerau U,  Rades T, A comparison of pseudo ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid film hydration and dialysis. Journal of Pharmacy and Pharmacology 56: 573-580 (2004). COLLOIDAL SYSTEMS
  57. McFetridge J, Rades T, Lim M, Influence of hydrogenated starch hydrolysates on the glass transition and crystallisation of sugar alcohols. Food Research International 37: 409-415 (2004).  SOLID STATE
  58. Strachan C, Howell SL, Rades T, Gordon KC, A theoretical and spectroscopic study of carbamazepine polymorphs. Journal of Raman Spectroscopy 35: 401-408 (2004). SOLID STATE
  59. Demana PH, Davies NM, Berger B, Rades T, Incorporation of ovalbumin into iscoms and related colloidal particles prepared by the lipid film hydration method. International Journal of Pharmaceutics 278: 263-274 (2004). COLLOIDAL SYSTEMS
  60. Songkro S, Becket G, Rades T, The effects of p-menthane monoterpenes and related compounds on the percoutaneous absorption of propranolol hydrochloride across newborn pig skin. Part III: Correlation between penetration enhancing activity and physicochemical properties of terpenes determined by principal component analysis. Journal of Drug Delivery Science and Technology 14: 223-228 (2004). TRANSDERMAL DELIVERY
  61. Demana P, Fehske C, White K, Rades T, Hook S, Effect of incorporation of the adjuvant Quil A on structure and immune stimulatory capacity of liposomes. Immunology and Cell Biology 82: 547-554 (2004). COLLOIDAL SYSTEMS
  62. Feltrin KL, Little TJ, Meyer JH, Horowitz M, Smout AJPM, Wishart J, Pilichiewicz AN, Rades T, Chapman IM, Feinle-Bisset C, Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility and plasma CCK and GLP-1 in humans vary with their chain length. American Journal of Physiology-Regulatory, Comparative and Integrative Physiology 287: 524-533 (2004). COLLOIDAL SYSTEMS
  63. Krauel K, Pitaksuteepong T,  Davies NM, Rades T, Entrapment of bioactive molecules in poly (alkylcyanoacrylate) nanoparticles. American Journal of Drug Delivery 2: 251-259 (2004). COLLOIDAL SYSTEMS
  64. Hachey MRJ, Bogomolov A, Gordon KC, Rades T, How using Raman spectroscopy and SIMPLISMA can accelerate the study of polymorphs: A case study using carbamazepine. Spectroscopy (2004), 19: 16-21 (2004). SOLID STATE
  65. Strachan CJ, Lee CJ, Rades T, Partial characterization of different mixtures of solids by measuring the optical nonlinear response. Journal of Pharmaceutical Sciences 93: 733-742 (2004). SOLID STATE
  66. 2005 66. Strachan CJ, Rades T, Lee CJ, Determination of the optical second harmonic response of pharmaceutical solid–solid mixtures. Optics and Lasers in Engineering 43: 209-220 (2005). SOLID STATE
  67. Strachan CJ, Taday PF, Newnham DA, Zeitler JA, Gordon KC, Pepper M, Rades T, Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity. Journal of Pharmaceutical Sciences 94: 837-846 (2005). SOLID STATE
  68. Copland MJ, Rades T, Davies NM, Baird M, Lipid based particulate formulations for the delivery of antigen. Immunology and Cell Biology 83: 97-105 (2005). COLLOIDAL SYSTEMS
  69. Bunjes H, Rades T, Thermotropic liquid crystalline drugs. Journal of Pharmacy and Pharmacology 57: 807-816 (2005). COLLOIDAL SYSTEMS
  70. Patterson J, James MB, Forster AH, Lancaster RW, Butler JM,  Rades T, The influence of thermal and mechanical preparative techniques on the amorphous state of four poorly soluble compounds. Journal of Pharmaceutical Sciences 94: 1998-2012 (2005). SOLID STATE
  71. Krauel K, Davies NM, Rades T, Using different structure types of microemulsions for the preparation of poly (alkylcyanoacrylate) nanoparticles by interfacial polymerization. Journal of Controlled Release 106: 76-87 (2005). COLLOIDAL SYSTEMS
  72. Lendemans DG, Myschik J, Hook S, Rades T, Immuno-stimulating complexes prepared by ethanol injection. Journal of Pharmacy and Pharmacology 57: 729-733 (2005). COLLOIDAL SYSTEMS
  73. Lendemans DG, Myschik J, Hook S, Rades T, Cationic Cage-like Complexes Formed by DC-cholesterol, Quil-A and Phospholipid. Journal of Pharmaceutical Sciences 94: 1794-1807(2005). COLLOIDAL SYSTEMS
  74. Zeitler JA,  Newnham DA, Taday PF Strachan CJ, Pepper M, Gordon KC, Rades T, Temperature Dependent Terahertz Pulsed Spectroscopy of Carbamazepine. Thermochimica Acta 436: 70-76 (2005). SOLID STATE
  75. Little TJ, Feltrin KL, Horowitz M, Smout AJPM, Rades T, Meyer JH, Pilichiewicz AN, Wishart J, Feinle-Bisset C, Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite and energy intake in healthy men.  American Journal of Physiology - Regulatory, Comparative and Integrative Physiology 289: 1090-1098 (2005). COLLOIDAL SYSTEMS
  76. Apperley DC, Forster AH, Fournier R, Harris RK, Hodgkinson P, Lancaster RW, Rades T, Characterisation of indomethacin and nifedipine using variable-temperature solid state NMR. Magnetic Resonance in Chemistry 43: 881-892 (2005). SOLID STATE
  77. Demana PH, Davies NM, Hook S, Rades T, Quil A-lipid powder formulations releasing ISCOMs and related colloidal structures upon hydration. Journal of Controlled Release 103: 45-59 (2005). COLLOIDAL SYSTEMS
  78. Tian F, Zeitler JA, Strachan CJ, Saville DJ, Gordon KC, Rades T, Characterizing the conversion kinetics of carbamazepine polymorphs to the dihydrate in aqueous suspension using Raman spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 40: 271-280 (2006). SOLID STATE
  79. Alany RG, Rades T, Nicoll TJ, Tucker IG, Davies NM, w/o Microemulsions for ocular delivery: Evaluation of ocular irritation and precorneal retention. Journal of Controlled Release 111: 145 - 152 (2006). COLLOIDAL SYSTEMS
  80. Rawle C, Lee C, Strachan CJ, Payne K, Manson P, Rades T, Towards Characterisation and Identification of Solid State Pharmaceutical Mixtures through Second Harmonic Generation. Journal of Pharmaceutical Sciences 95: 761 – 768 (2006). SOLID STATE
  81. Day GA, Zeitler JA, Jones W, Rades T, Taday P, Understanding the influence of polymorphism on phonon spectra: lattice dynamics calculations and terahertz spectroscopy of carbamazepine. Journal of Physical Chemistry B 110: 447 – 456 (2006). SOLID STATE
  82. Tantipolphan R, Rades T, Strachan CJ, Gordon KC, Medlicott N, Analysis of lecithin-cholesterol mixtures using Raman spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 41: 476 - 484 (2006). COLLOIDAL SYSTEMS
  83. Saupe A, Gordon KC, Rades T, Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy. International Journal of Pharmaceutics 314: 56 - 62 (2006). COLLOIDAL SYSTEMS
  84. Thompson AK, Hindmarsh JP, Haisman D, Rades T, Singh H, Comparison of the structure and properties of liposomes prepared from milk fat globule membrane and soya phospholipids. Journal of Agricultural and Food Chemistry 54: 3704 - 3711 (2006). COLLOIDAL SYSTEMS
  85. Boonme P, Krauel K, Graf A, Rades T, Junyaprasert VB, Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate /water/Brij 97:1-Butanol. AAPS PharmSciTech.  7(2): Article 45 (2006). COLLOIDAL SYSTEMS
  86. White K, Rades T, Fernaux RH, Tyler PC, Hook S, Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells.  Journal of Pharmacy and Pharmacology 58: 729 - 737 (2006). COLLOIDAL SYSTEMS
  87. Flanagan J, Kortegaard K, Pinder N, Rades T, Singh H, Solubilisation of soybean oil in microemulsions using food-grade surfactants. Food Hydrocolloids 20: 253-260 (2006). COLLOIDAL SYSTEMS
  88. Saupe A, McBurney WT, Rades T, Hook SJ, Immunostimulatory colloidal delivery systems for cancer vaccines. Expert Opinion on Drug Delivery 3: 345 - 354 (2006). COLLOIDAL YSTEMS
  89. White K, Rades T, Fernaux R, Kearns P, Toth I, Hook S, Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research 23: 1473 – 1481 (2006). COLLOIDAL SYSTEMS
  90. Lendemans DG, Egert AM, Myschik J, Hook S, Rades T, On the dilution behaviour of immuno-stimulation complexes. Die Pharmazie 61: 689 - 695 (2006). COLLOIDAL SYSTEMS
  91. Myschik J, Lendemans DG, McBurney WT, Demana P, Hook S, Rades T, On the preparation, microscopic investigation and application of ISCOMs. Micron 37: 724 - 734 (2006). COLLOIDAL SYSTEMS
  92. Krauel K, Graf A, Hook SM, Davies NM, Rades T, Preparation of poly (alkylcyanoacrylate) nanoparticles by polymerisation of water-free microemulsions. Journal of Microencapsulation: 23: 499 – 512 (2006). COLLOIDAL SYSTEMS
  93. Zeitler JA, Newnham DA, Taday PF, Threlfall TL, Lancaster RW, Berg RW, Strachan CJ, Gordon KC, Pepper M, Rades T, Characterisation of temperature induced phase transitions in the five polymorphic forms of sulfathiazole by terahertz pulsed spectroscopy and differential scanning calorimetry. Journal of Pharmaceutical Sciences 95: 2486 - 2498 (2006). SOLID STATE
  94. Tian F, Sandler N, Gordon KC, McGoverin C, Reay, A, Strachan CJ, Saville DJ, Rades T, Visualization of conversion of carbamazepine in aqueous suspension with and without the presence of excipients: a single crystal study using SEM and Raman microscopy. European Journal of Pharmaceutics and Biopharmaceutics 64: 326 - 335 (2006). SOLID STATE
  95. Chieng N, Zujovic Z, Rades T, Saville D, Effect of milling conditions on the solid-state conversion of ranitidine hydrochloride form 1. International Journal of Pharmaceutics 327: 36 - 44 (2006). SOLID STATE
  96. Strachan CJ Ho L, Zeitler JA, Rantanen J, Rades T, Gordon KC, Terahertz applications for the analysis of solid dosage forms. Pharmaceutical Technology Europe 18 (11): 27 - 33 (2006). SOLID STATE
  97. McGoverin CM, Ho LCH, Zeitler JA, Strachan CJ, Gordon KC, Rades T, Quantification of binary polymorphic mixtures of ranitidine hydrochloride using NIR spectroscopy. Vibrational Spectroscopy 41: 225 - 231 (2006). SOLID STATE
  98. Yotsawimonwat S, Okonoki S, Krauel K, Sirithunyalug J, Sirithunyalug B, Rades T, Characterization of microemulsions containing orange oil with water and propylene glycol as hydrophilic phases Die Pharmazie 61: 920 - 926  (2006). COLLOIDAL SYSTEMS
  99. Boonme VP, Krauel K, Graf A, Rades T, Junyaprasert VB, Characterisation of microstructures formed in isopropyl palmitate/water/Aerosol®OT:1-butanol (2:1) system. Die Pharmazie 61: 927 – 932 (2006). COLLODAL SYSTEMS
  100. McDowell A, McLeod BJ, Rades T, Tucker IG, Application of pharmaceutical drug delivery for biological control of the common brushtail possum in New Zealand – a review. Wildlife Research 33: 679-689 (2006). COLLOIDAL SYSTEMS
  101.  Zeitler JA, Shen Y, Baker C, Taday PF, Pepper M, Rades T, Analysis of coating structures and interfaces in solid oral dosage forms by three dimensional terahertz pulsed imaging. Journal of Pharmaceutical Sciences 96: 330 - 340 (2007). SOLID STATE
  102. Strachan CJ, Rades T, Gordon KC, Rantanen J, Raman spectroscopy for quantitative analysis of pharmaceutical solids. Journal of Pharmacy and Pharmacology 59: 179 – 192 (2007). SOLID STATE
  103. Tian F, Saville DJ, Gordon KC, Strachan JC, Zeitler JA, Sandler N, Rades T, The influence of various excipients on the conversion kinetics of carbamazepine polymorphs in aqueous suspension. Journal of Pharmacy and Pharmacology 59: 193 – 201 (2007). SOLID STATE
  104. Zeitler JA, Taday PF, Newnham DA, Pepper M, Gordon KC, Rades T, Terahertz pulsed spectroscopy and imaging in the pharmaceutical setting. Journal of Pharmacy and Pharmacology 59: 209 – 223 (2007). SOLID STATE
  105. Lee CJ, Strachan CJ, Manson PJ, Rades T, Characterisation of the bulk properties of pharmaceutical solids using nonlinear optics – a review. Journal of Pharmacy and Pharmacology 59: 241 – 250 (2007). SOLID STATE
  106. Strachan CJ, Rades T, Gordon KC, A theoretical and spectroscopic study of γ-crystalline and amorphous indomethacin. Journal of Pharmacy and Pharmacology 59: 261 – 269 (2007). SOLID STATE
  107. Gordon KC, McGoverin CM, Strachan CJ, Rades T, The use of quantum chemistry in pharmaceutical research as illustrated by case studies of indomethacin and carbamazepine. Journal of Pharmacy and Pharmacology 59: 271 – 277 (2007). SOLID STATE
  108. Savolainen M, Heinz A, Strachan CJ, Gordon KC, Yliruusi J, Rades T, Sandler N, Screening for differences in the amorphous state of indomethacin using multivariate visualization. European Journal of Pharmaceutical Sciences 30: 113 - 123 (2007). SOLID STATE
  109. Tian F, Sandler N, Aaltonen J, Lang C, Saville DJ, Gordon KC, Strachan JC, Rantanen J, Rades T, Influence of polymorphic form, morphology and excipient interactions on the dissolution of carbamazepine compacts.  Journal of Pharmaceutical Sciences 96: 584 – 594 (2007). SOLID STATE
  110. Lendemans DG, Egert AM, Hook S, Rades T, Cage-like complexes formed by DOTAP, Quil-A and cholesterol. International Journal of Pharmaceutics 332: 192 – 195 (2007). COLLOIDAL SYSTEMS
  111. Sandler N, Savolainen M,  Saupe A, Strachan C, Rades T, Applications of Raman spectroscopy in aqueous environments. Pharmaceutical Technology Europe 19 (2): 24 – 29 (2007). SOLID STATE
  112. Zeitler JA, Kogermann K, Rantanen J, Rades T, Taday PF,  Pepper M,  Aaltonen J,  Strachan CJ,  Drug hydrate systems and dehydration processes studied by terahertz pulsed spectroscopy. International Journal of Pharmaceutics 334: 78 – 84 (2007). SOLID STATE
  113. Patterson JE, James MB, Forster AH, Lancaster RW, Butler JM. Rades T, Preparation of glass solutions of three water soluble drugs by spray drying, melt extrusion and ball milling. International Journal of Pharmaceutics 336: 22 – 34 (2007). SOLID STATE
  114. Feltrin KL, Little TJ, Meyer JH, Horowitz M, Rades T, Wishart J, Feinle-Bisset C,  Effects of lauric acid on antropyloroduodenal motility, plasma CCK and PYY,  appetite and energy intake are dependent on load, but not concentration, in healthy humans. Journal of Physiology 581:2 767 – 777 (2007) COLLOIDAL SYSTEMS
  115. Tian F, Zhang F, Sandler N, Gordon KC, McGoverin CM, Strachan CJ, Saville DJ,  Rades T, Influence of sample characteristics on quantification of carbamazepine hydrate formation by X-ray powder diffraction and Raman spectroscopy. European Journal of Pharmaceutics and Biopharmaceutics 66: 466 – 474 (2007). SOLID STATE
  116. Junyaprasert VB, Boonme P, Songkro S, Krauel K, Rades T, Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions. Journal of Pharmacy and Pharmaceutical Sciences 10: 288-298 (2007). COLLOIDAL SYSTEMS
  117. Tantipolphan R, Rades T, McQuillan J, Medlicott NJ, Adsorption of bovine serum albumin (BSA) onto lecithin studied by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. International Journal of Pharmaceutics 337: 40 – 47 (2007). COLLOIDAL SYSTEMS
  118. Rizwan SB, Dong Y, Boyd BJ, Rades T, Hook S, Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM). Micron 38: 478 – 485 (2007). COLLOIDAL SYSTEMS
  119. Ho L, Müller R, Römer M, Gordon KC, Heinämäki J, Kleinebudde P, Pepper M, Rades T,  Shen YC, Strachan CJ, Taday PF, Zeitler J, Analysis of Sustained-Release Tablet Film Coats using Terahertz Pulsed Imaging. Journal of Controlled Release 119: 253–261 (2007) SOLID STATE
  120. Zeitler JA, Taday PF, Pepper M, Rades T, Crystallisation of amorphous carbamazepine studied by terahertz pulsed spectroscopy. Journal of Pharmaceutical Sciences 96: 2703 – 2709 (2007). SOLID STATE
  121. Demana PH, Nigel M. Davies NM, Sarah Hook S, Rades T, Analysis of Quil A-phospholipid mixtures using drift spectroscopy. International Journal of Pharmaceutics 342: 49 – 61 (2007). COLLOIDAL SYSTEMS
  122. Zeitler JA, Taday PF, Gordon KC, Pepper M, Rades T, New insights into the solid state transition mechanism of carbamazepine polymorphs by time resoled terahertz pulsed spectroscopy. ChemPhysChem 8: 1924 – 1927 (2007).  SOLID STATE
  123. Heinz A, Savolainen M, Rades T, Strachan CJ, Quantifying ternary mixtures of different solid state forms of indomethacin by Raman and near-infrared spectroscopy. European Journal of Pharmaceutical Sciences 32: 182 – 192 (2007). SOLID STATE
  124. Krauel K, Girvan L, Hook S, Rades T, Characterisation of colloidal drug delivery systems - from the naked eye to cryoFESEM. Micron 38: 796 – 803 (2007). COLLOIDAL SYSTEMS
  125. Siow LF, Rades T, Lim MH, Characterizing the freezing behaviour of liposomes as a tool to understand cryopreservation procedures. Cryobiology 55: 210 – 221 (2007). COLLOIDAL SYSTEMS
  126. Siow LF, Rades T, Lim MH, Effect of intra/extra liposomal distribution of sodium chloride on the stability of large unilamellar vesicles. CryoLetters 28: 429 - 444 (2007). COLLOIDAL SYSTEMS
  127. Boyd B, Rizwan S, Dong Y-D, Hook S, Rades T, Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions - hexosomes are not necessarily flat hexagonal prisms. Langmuir 23: 12461-12464 (2007). COLLOIDAL SYSTEMS
  128. Kogermann K, Zeitler JA, Rantanen J, Rades T, Taday PF, Pepper M, Heinämäki J, Strachan CJ, Investigating dehydration from compacts using terahertz pulsed, Raman and near-infrared spectroscopy. Applied Spectroscopy 61: 1265 - 1274 (2007). SOLID STATE
  129. Heinz A, Atassi F, Gordon KC, Rades T, Characterizing an amorphous system exhibiting trace crystallinity: a case study with saquinavir. Crystal Growth & Design 8: 119-127 (2008). SOLID STATE
  130. Graeser K, Strachan CJ, Patterson JE, Gordon KC, Rades T, Physico-chemical properties and stability of two differently prepared amorphous forms of simvastatin. Crystal Growth & Design 8: 128-135 (2008). SOLID STATE
  131. Patterson JE, James MB, Forster AH, Rades T, Melt extrusion and spray drying of carbamazepine and dipyridamole with polyvinylpyrrolidone/vinyl acetate copolymers. Drug Development and Industrial Pharmacy 34: 95 – 106 (2008). SOLID STATE    132. Graf A, Ablinger E, Peters S, Zimmer A, Hook S, Rades T, Microemulsions containing lecithin and sugar-based surfactants: nanoparticle templates for delivery of proteins and peptides. International Journal of Pharmaceutics 350: 351 – 360 (2008). COLLOIDAL SYSTEMS
  132. Myschik J, Eberhardt F, Rades T, Hook S, Immunostimulatory biodegradable implants containing the adjuvant Quil-A – Part I: Physicochemical characterisation. Journal of Drug Targeting 16: 213 – 223 (2008). COLLOIDAL SYSTEMS
  133. Myschik J, McBurney WT, Hennessy T, Phipps-Green A, Rades T, Hook S, Immunostimulatory biodegradable implants containing the adjuvant Quil-A – Part II: In vivo evaluation. Journal of Drug Targeting 16: 224 – 232 (2008). COLLOIDAL SYSTEMS
  134. Chieng N, Rades T, Saville D, Formation and physical stability of the amorphous phase of ranitidine hydrochloride polymorphs prepared by cryo-milling. European Journal of Pharmaceutics and Biopharmaceutics 68: 771 – 780 (2008). SOLID STATE
  135. Khunawattanakul W, Puttipipatkhachorn S, Rades T, Pongjanyakul T, Chitosan - magnesium aluminum silicate composite dispersions: Characterization of rheology, flocculate size and zeta potential. International Journal of Pharmaceutics 351: 227 – 235 (2008). COLLOIDAL SYSTEMS
  136. Ho L, Müller R, Gordon KC, Kleinebudde P, Pepper M, Rades T, Shen YC, Taday PF, Zeitler J, Applications of terahertz pulsed imaging to sustained-release tablet film coating quality assessment and dissolution performance. Journal of Controlled Release 129: 78 – 87 (2008). SOLID STATE
  137. Graf A, Jack KS, Whittaker AK, Hook SM, Rades T, Protein delivery using nanoparticles based on microemulsions with different structure-types. European Journal of Pharmaceutical Sciences 33: 434 – 444 (2008). COLLOIDAL SYSTEMS
  138. Feltrin KL, Little TJ, Meyer JH, Horowitz M, Rades T, Wishart J, Feinle-Bisset C, Comparative effects of intraduodenal administration of lauric and oleic acids on antropyloroduodenal motility, plasma cholecystokinin and peptide YY, and energy intake in healthy males. American Journal of Clinical Nutrition 87: 1181 - 1187 (2008) COLLOIDAL SYSTEMS
  139. Tantipolphan R, Rades T, Medlicott NJ, Insights into the structure of protein by vibrational spectroscopy. Current Pharmaceutical Analysis 4: 53 – 68 (2008). COLLOIDAL SYSTEMS
  140.  Junyaprasert VB, Boonme P, Wurster DE, Rades T, Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anaesthetics. Drug Delivery 15: 323 - 330 (2008). COLLOIDAL SYSTEMS
  141. McBurney WT, Lendemans DG, Myschik J, Hennessy T, Rades T, Hook S, In vivo activity of cationic immune stimulating complexes (PLUSCOMs). Vaccine 26: 4549 – 4556 (2008). COLLOIDAL SYSTEMS
  142. Sandler N, Tian F, Rades T, Visualizing solvent mediated phase transformation behavior of carbamazepine polymorphs by principal component analysis. AAPS PharmSciTech 9: 390-394 (2008). SOLID STATE
  143. McGoverin C, Rades T, Gordon KC, Recent pharmaceutical applications of Raman and terahertz spectroscopies. Journal of Pharmaceutical Sciences 97: 4598 - 4621 (2008). SOLID STATE
  144. Wiranidchapong C, Tucker IG, Rades T, Kulvanich P, Miscibility and interactions between 17β-estradiol and Eudragit  RS in Solid Dispersion. Journal of Pharmaceutical Sciences 97: 4879 - 4888 (2008). SOLID STATE
  145. Myschik J, McBurney WT, Rades T, Hook S, Immunostimulatory lipid implants containing Quil-A and DC-cholesterol. International Journal of Pharmaceutics 363: 91 – 98 (2008). COLLOIDAL SYSTEMS
  146. Myschik J, Hennessy T, McBurney WT, Phipps-Green A,  Rades T,  Hook S, Immunogenicity of lipid sustained release implants containing imiquimod, α-Galactosylceramide, or Quil-A. Die Pharmazie 63: 686 – 692 (2008). COLLOIDAL SYSTEMS
  147. Gordon S, Saupe A, McBurney W, Rades T, Hook S, Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery. Journal of Pharmacy and Pharmacology 60: 1591 – 1600 (2008). COLLOIDAL SYSTEMS
  148. Aaltonen J, Gordon KC, Strachan CJ, Rades T, Perspectives in the use of spectroscopy to characterise pharmaceutical solids. International Journal of Pharmaceutics 364: 158 – 169 (2008). SOLID STATE
  149. Siow LF, Rades T, Lim MH, Cryo-responses of two types of large unilamellar vesicles in the presence of non-permeable or permeable cryoprotecting agents. Cryobiology 57: 276 – 285 (2008). COLLOIDAL SYSTEMS
  150. Chieng N, Aaltonen J, Saville D, Rades T, Physical characterization and stability of amorphous indomethacin and ranitidine hydrochloride binary systems prepared by mechanical activation. European Journal of Pharmaceutics and Biopharmaceutics 71: 47 – 54 (2009). SOLID STATE
  151. Zhang F, Jaakko Aaltonen J, Tian F, Saville DJ, Rades T, Influence of particle size and preparation methods on the physical and chemical stability of amorphous simvastatin. European Journal of Pharmaceutics and Biopharmaceutics 71: 64 – 70 (2009). SOLID STATE
  152. Heinz A, Gordon KC, McGoverin CM, Rades T, Strachan CJ, Understanding the solid state forms of fenofibrate – a spectroscopic and computational study. European Journal of Pharmaceutics and Biopharmaceutics 71: 100 – 108 (2009). SOLID STATE
  153. Ho L, Mueller R, Gordon KC, Kleinebudde P, Pepper M, Rades T, Shen Y, Taday PF, Zeitler JA, Terahertz pulsed imaging as an analytical tool for sustained-release tablet film coating. European Journal of Pharmaceutics and Biopharmaceutics 71: 117 – 123 (2009). SOLID STATE
  154. Tan A, Simovic S, Davey AK, Rades T, Prestidge CA, Silica nanoparticle-lipid hybrid capsules: a novel oral delivery system for poorly soluble drugs. Journal of Controlled Release 134: 62 – 70 (2009) COLLOIAL SYSTEMS
  155. Chieng N, Rehder S, Saville D, Rades T, Aaltonen J, Quantitative solid-state analysis of three solid forms of ranitidine hydrochloride in ternary mixtures using Raman spectroscopy and X-ray powder diffraction. Journal of Pharmaceutical and Biomedical Analysis 49: 18 – 25 (2009). SOLID STATE
  156. Myschik J, Rades T, Hook S, Advances in lipid-based subunit vaccine formulations. Current Immunology Reviews 5: 42 – 48 (2009) COLLOIDAL SYSTEMS
  157. Wiranidchapong C, Rades T, Kulvanichc P, Tucker IG, Method of preparation does not affect the miscibility between steroid hormone and polymethacrylate. Thermochimica Acta 485: 57 – 64 (2009). SOLID STATE
  158. Boyd BJ, Dong Y, Rades T, Non-lamellar liquid crystalline nanostructured particles – advances in materials and structure determination. Journal of Liposome Research 19: 12 – 28 (2009). COLLOIDAL SYSTEMS
  159. Tantipolphan R, Rades T, Medlicott NJ, Swelling lecithin:cholesterol implants for the controlled release of proteins.  Journal of Liposome Research 19: 37 – 48 (2009) .COLLOIDAL SYSTEMS
  160. Graf A, Rades T, Hook S, Oral insulin delivery using nanoparticles based on microemulsions with different structure-types: Optimisation and in vivo evaluation. European Journal of Pharmaceutical Sciences 37: 53-61 (2009). COLLOIDAL SYSTEMS
  161. Greatrex BW, Brodie SJ, Furneaux RH, Hook SM, McBurney WT, Painter GF, Rades T, Rendle PM, The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers. Tetrahedron 65: 2939 - 2950 (2009). COLLOIDAL SYSTEMS
  162. Songkro S, Rades T, Becket G, Effects of some terpenes on the in vitro permeation of LHRH through newborn pig skin. Die Pharmazie 64: 110 - 115 (2009). COLLOIDAL SYSTEMS
  163. Allesø M, Chieng N, Rehder S, Rantanen J, Rades T, Aaltonen J, Enhanced dissolution rate and synchronized release of drugs in binary systems through formulation: Amorphous naproxen-cimetidine mixtures prepared by mechanical activation. Journal of Controlled Release 136: 45 – 53 (2009). SOLID STATE
  164. Chieng N, Hubert M, Saville D, Rades T, Aaltonen J, Formation kinetics and stability of carbamazepine-nicotinamide co-crystals prepared by mechanical activation. Journal of Crystal Growth and Design 9: 2377 - 2386 (2009). SOLID STATE
  165. Graeser KA, Patterson JE, Zeitler JA, Gordon KC, Rades T, Correlating thermodynamic and kinetic parameters with amorphous stability. European Journal of Pharmaceutical Sciences 37: 492 – 498 (2009). SOLID STATE
  166. Prestidge C, Spomenka S, Heard P,  Hui H,  Song, Y, Peddie F, Davey A, Andrew L, Rades T, Dry hybrid lipid-silica microcapsules engineered from submicron lipid droplets and nanoparticles as a novel delivery system for poorly soluble drugs. Molecular Pharmaceutics 6: 861 – 872 (2009). COLLOIDAL SYSTEMS
  167. Aaltonen J, Rades T, Towards physico-relevant dissolution testing: the importance of solid-state analysis in dissolution. Dissolution Technology 5: 47 – 54 (2009). SOLID STATE
  168. Baeumer B, Chatterjee L, Hino P, Rades T, Radunskaya A, Tucker I, Predicting the drug release kinetics of matrix tablets. Discrete and Continuous Dynamical Systems 12: 261 – 276 (2009). SOLID STATE
  169. Daines AM, Greatrex BW, Hayman CM, Hook S, McBurney WT, Rades T,  Rendle PM, Sims IM, Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems. Bioorganic and Medicinal Chemistry 17: 5207 – 5218 (2009). COLLOIDAL SYSTEMS
  170. Heinz A, Strachan CJ, Gordon KC, Rades T, Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy. Journal of Pharmacy and Pharmacology 61: 971 – 988 (2009). SOLID STATE
  171. Graeser KA, Patterson JE, Rades T, Applying thermodynamic and kinetic parameters to predict the physical stability of two differently prepared amorphous forms of simvastatin. Current Drug Delivery 6: 374 – 382 (2009). SOLID STATE
  172. Kafka A, Kleffmann, Rades T, McDowell A, Histidine residues in the peptide D-Lys6GnRH:  Potential for co-polymerization in polymeric nanoparticles. Molecular Pharmaceutics 6: 1483 – 1491 (2009). COLLOIDAL SYSTEMS
  173. Rizwan SB, Hanley T, Boyd BJ, Rades T, Hook S, Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: characterisation, swelling and release kinetics. Journal of Pharmaceutical Sciences 98: 4191 - 4204 (2009). COLLOIDAL SYSTEMS
  174. Ho L, Müller R, Gordon KC, Kleinebudde P, Pepper M, Rades T, Shen Y, Taday PF, Zeitler JA, Monitoring the film coating unit operation and predicting drug dissolution using terahertz pulsed imaging. Journal of Pharmaceutical Sciences 98: 4866 – 4876 (2009). SOLID STATE
  175. Graf A, McDowell A, Rades T, Poly(alkylcyanoacrylate) nanoparticles for enhanced delivery of therapeutics – is there real potential? Expert Opinion on Drug Delivery 6: 371 - 387 (2009). COLLOIDAL SYSTEMS
  176. Patel A, Gould R, Norris P, Rades T, Drug quality in South Africa: perceptions of key players involved in medicines distribution. International Journal of Health Care Quality Assurance 22: 547 - 560 (2009).
  177. Ferderber K, Rades T, Hook S, Phosphatidylcholine based colloidal systems for dermal and transdermal delivery. Journal of Liposome Research 19: 267 – 277 (2009). COLLOIDAL SYSTEMS
  178. Ho L, Cuppok Y, Muschert S, Gordon KC, Pepper M,  Shen Y, Siepmann F, Siepmann J, Taday PF, Rades T, Effects of film coating thickness and drug layer uniformity on in-vitro drug release from sustained-release coated pellets: A case study using terahertz pulsed imaging. International Journal of Pharmaceutics 382: 151 – 159 (2009). SOLID STATE
  179. Kaur  R, Morris R, Bencsik M, Vangala A, Rades T, Perrie Y, Development of a novel magnetic resonance imaging contrast agent for pressure measurements using lipid-coated gas filled microbubbles and nanobubbles. Journal of Biomedical Nanotechnology 5: 707-715 (2009). COLLOIDAL SYSTEMS
  180. Chatterjee L, Rades T, Tucker IG, Mechanical properties of excipients do not af1ct polymer matrix formation. International Journal of Pharmaceutics 384: 87 - 92 (2010). SOLID STATE
  181. Kafka A, Rades T, McDowell A, Rapid and specific high-performance liquid chromatography for the in vitro quantification of D-Lys6-GnRH in a microemulsion-type formulation in the presence of peptide oxidation products. Biomedical Chromatography 24: 132 – 139 (2010). COLLOIDAL SYSTEMS
  182. Ho L, Krüger C, Müller R, Gordon KC, Kleinebudde P, Pepper M, Rades T, Shen Y, Taday PF, Zeitler JA, Investigating dissolution performance critical areas on coated tablets: A case study using terahertz pulsed imaging. Journal of Pharmaceutical Sciences 99: 392 - 402 (2010). SOLID STATE
  183. Patel A, Norris P, Gould R, Rades T, "This body does not want free medicines": South African consumer perceptions of drug quality. Health Policy and Planning 25: 61 - 69 (2010).
  184. Zimper U, Aaltonen J, McGoverin CM, Gordon KC, Krauel-Goellner K, Rades T, Quantification of process induced disorder in milled samples using different analytical techniques. Pharmaceutics 2: 30 – 49 (2010). SOLID STATE
  185. Glaessl B, Siepmann F, Tucker I, Rades T, Siepmann J, Deeper insight into the drug release mechanisms in Eudragit RL-based delivery systems. International Journal of Pharmaceutics 389: 139 – 146 (2010). SOLID STATE
  186. Graeser KA, Patterson JE, Zeitler JA, Rades T, The role of configurational entropy in amorphous systems. Pharmaceutics 2: 224-244 (2010). SOLID STATE
  187. Simovic S, Hui H, Song Y, Davey AK, Rades T, Prestidge CA, An oral delivery system for indomethicin engineered from cationic lipid emulsions and silica nanoparticles. Journal of Controlled Release 143: 367-373 (2010). COLLOIDAL SYSTEMS
  188. Khunawattanakul W, Puttipipatkhachorn S, Rades T, Pongjanyakul T, Chitosan-magnesium aluminum silicate nanocomposite films: Physicochemical characterization and drug permeability. International Journal of Pharmaceutics 393: 220-230 (2010). COLLOIDAL SYSTEMS
  189. Prestidge C, Tan A, Simovic S, Davey A, Rades T, Boyd B, Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems. Molecular Pharmaceutics 7:  522–532 (2010). COLLOIDAL SYSTEMS
  190. Gordon S, Teichmann E, Young K, Finnie K, Rades T, Hook S, In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery. European Journal of Pharmaceutical Sciences 41: 360-368 (2010). COLLOIDAL SYSTEMS
  191. Kafka A, Rades T, McDowell A, Characterization of peptide polymer interactions in poly(alkylcyanoacrylate) nanoparticles: a mass spectrometric approach. Current Drug Delivery 7: 208-215 (2010). COLLOIDAL SYSTEMS
  192. Glaessl B, Siepmann F, Tucker I, Rades T, Siepmann J, Mathematical modelling of drug release from Eudragit RS-based delivery systems. Journal of Drug Delivery Science and Technology 20: 127-133 (2010). SOLID STATE
  193. Rizwan SB, Assmus D, Boehnke A, Hanley T, Boyd BJ, Rades T, Hook S, Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines. Expert Opinion on Drug Delivery 7: 1133-1144 (2010).  COLLOIDAL SYSTEMS
  194. Müllertz A, Ogbonna A, Ren S, Rades T, New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs. Journal of Pharmacy and Pharmacology 62: 1622-1636 (2010). COLLOIDAL SYSTEMS
  195. Sassene PJ, Knoop M, Hesselkilde JZ, Koradia V, Larsen A, Rades T, Müllertz A, Precipitation of a poorly soluble model drug during in vitro lipolysis – characterization and dissolution of the precipitate. Journal of Pharmaceutical Sciences 99: 4982-4991 (2010). COLLOIDAL SYSTEMS
  196. Zimper U, Aaltonen J, Krauel-Goellner K, Gordon KC, Strachan CJ, Rades T, The influence of milling on the dissolution performance of simvastatin. Pharmaceutics 2: 419-431 (2010). SOLID STATE
  197.  Khunawattanakul W, Puttipipatkhachorn S, Rades T, Pongjanyakul T, Novel chitosan-magnesium aluminum silicate nanocomposite film coatings for modified release tablets. International Journal of Pharmaceutics 407: 132-141 (2011). COLLOIDAL SYSTEMS
  198. Zhong S, Shen YC, Ho L, May R, Zeitler JA, Evans M, Taday PT, Pepper M, Rades T, Gordon KC, Muller R, Kleinebudde P, Nondestructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography. Optics and Lasers in Engineering 49: 361-365 (2011). SOLID STATE
  199. Kafka AP, Rades T, McDowell A, Release and bioactivity of PACA nanoparticles containing D-Lys6-GnRH for brushtail possum fertility control. Journal of Controlled Release 149: 307-313 (2011). COLLOIDAL SYSTEMS
  200. Chieng N, Rades T, Aaltonen J, An overview of recent studies on the analysis of pharmaceutical polymorphs. Journal of Pharmaceutical and Biomedical Analysis 55: 618 - 644 (2011). SOLID STATE
  201. Kafka AP, Kleffmann T, Rades T, McDowell A, The application of MADLI TOF MS in biopharmaceutical research. International Journal of Pharmaceutics 417: 70 - 82 (2011). COLLOIDAL SYSTEMS
  202. Karmwar P, Graeser K, Gordon KC, Strachan CJ, Rades T, Investigation of properties and recrystallisation behaviour of amorphous indomethacin samples prepared by different methods. International Journal of Pharmaceutics 417: 94 - 100 (2011). SOLID STATE
  203. Bøtker JP, Karmwar P, Strachan CJ, Cornett C, Tian F, Zujovic Z, Rantanen J, Rades T, Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions. International Journal of Pharmaceutics 417: 112 - 119 (2011). SOLID STATE
  204. Rizwan SB, Assmus D, Boehnke A, Hanley T, Boyd BJ, Rades T,  Hook S, Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines. European Journal of Pharmaceutics and Biopharmaceutics 79: 15 - 22 (2011). COLLOIDAL SYSTEMS
  205. Haaser M, Windbergs M, McGoverin CM, Kleinebudde P, Rades T, Gordon KC, Strachan CJ, Analysis of matrix dosage forms during dissolution testing using Raman microscopy. Journal of Pharmaceutical Sciences 100: 4452 - 4459 (2011). SOLID STATE
  206. Karmwar P, Bøtker J, Graeser K, Strachan CJ, Rantanen J, Rades T, Investigations on the effect of different cooling rates on the stability of amorphous indomethacin. European Journal of Pharmaceutical Sciences 44: 341 - 350 (2011). SOLID STATE
  207. Rehder S, Klukkert M, Löbmann K, Strachan C, Sakmann A, Rades T, Leopold C, Investigation of the formation process of two piracetam cocrystals during grinding. Pharmaceutics 3:  706 - 722 (2011). SOLID STATE
  208. Wu JX, Yang M, van den Berg F, Pajander J, Rades T, Rantanen J, Influence of evaporation rate and formulation factors on solid dispersion physical stability. European Journal of Pharmaceutical Sciences 44: 610-620 (2011). SOLID STATE
  209. Bøtker JP, Savolainen M, Koradia V, Fang T, Rades T, Mullertz A, Cornett C, Rantanen J, Ostergaard J, Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy. Molecular Pharmaceutics 8: 1372-1380 (2011). SOLID STATE
  210. Loebmann K, Laitinen R, Grohganz H, Gordon KC, Strachan CJ, Rades T, Co-amorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen. Molecular Pharmaceutics 8: 1919-1928 (2011). SOLID STATE
  211. Kojarunchitt T, Hook S, Rizwan S, Rades T, Baldursdottir S, Development and characterisation of modified Poloxamer 407 thermoresponsive depot systems containing cubosomes. International Journal of Pharmaceutics 408: 20 – 26 (2011). COLLOIDAL SYSTEMS
  212.  Pirayavaraporn C, Rades T, Tucker IG, Determination of Moisture Content in Relation to Thermal Behaviour and Plasticization of Eudragit RLPO. International Journal of Pharmaceutics 442: 68–74 (2012). SOLID STATE
  213. Rehder S, Sakmann A, Rades T, Leopold CS, Thermal degradation of amorphous glibenclamide. European Journal of Pharmaceutics and Biopharmaceutics 80: 203 - 208 (2012). SOLID STATE
  214. Thomas N, Müllertz A, Graf A, Rades T, Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems (SNEDDS). Journal of Pharmaceutical Sciences 101: 1721-1731 (2012). COLLOIDAL SYSTEMS
  215. Naelapää K, Johan Peter Bøtker, Veski P, Rantanen J, Rades T, Kogermann K, Polymorphic form of piroxicam influences the performance of amorphous material prepared by ball-milling. International Journal of Pharmaceutics 429: 69 – 77 (2012). SOLID STATE
  216. Karmwar P, Graeser K, Gordon KC, Strachan CJ, Rades T, Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin.  European Journal of Pharmaceutics and Biopharmaceutics 80: 458 – 464 (2012). SOLID STATE
  217. Kao JY, McGoverin CM, Graeser KA, Rades T, Gordon KC, Measuring recrystallization of amorphous indomethacin using near infrared and Raman spectroscopic techniques. Vibrational Spectroscopy 58: 19 – 26 (2012). SOLID STATE
  218. Thomas N, Holm R, Müllertz A, Rades T, In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (S-SNEDDS). Journal of Controlled Release 160: 25 - 32 (2012). COLLOIDAL SYSTEMS
  219. Munk T, Baldursdottir S,  Hietala S,  Rades T,  Kapp S, Nuopponen M, Kalliomäki K,  Tenhu H, Rantanen J, Crystal morphology modification by the addition of tailor-made stereocontrolled poly(N-isopropyl acrylamide). Molecular Pharmaceutics 9: 1932 – 1941 (2012). SOLID STATE
  220. Löbmann K, Strachan C, Grohganz H, Rades T, Korhonen O, Laitinen R, Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions. European Journal of Pharmaceutics and Biopharmaceutics 81: 159 - 169 (2012). SOLID STATE
  221. Bøtker J, Koradia V, Rades T, Rantanen J, Savolainen M, Atomic pairwise distribution function analysis of the amorphous phase prepared by different manufacturing routes. Pharmaceutics 4: 93 - 103 (2012). SOLID STATE
  222. Gordon S, Young K, Wilson R, Rizwan S, Kemp R, Rades T, Hook S, Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research 22: 193 – 204 (2012). COLLOIDAL SYSTEMS
  223. Xia D, Wu JX, Cui F, Qu H, Rades T, Rantanen J, Yang M, Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers. European Journal of Pharmaceutical Sciences 46: 446 - 454 (2012). SOLID STATE
  224. Hagner Nielsen L, Keller S, Gordon KC, Boysen A, Rades T, Müllertz A, Spatial confinement can lead to increased stability of amorphous indomethacin. European Journal of Pharmaceutics and Biopharmaceutics 81: 418 - 425 (2012). SOLID STATE
  225. Rattanapak T, Young K, Rades T, Hook S, Comparative Study of Liposomes, Transfersomes, Ethosomes and Cubosomes for Transcutaneous Immunisation: Characterisation and in vitro skin penetration. Journal of Pharmacy and Pharmacology 64:1560 - 1569 (2012). COLLOIDAL SYSTEMS
  226. Priemel PA, Grohganz H,  Gordon KC, Rades T, Strachan CJ, The impact of surface- and nano- crystallisation on the detected amorphous content and the dissolution behaviour of amorphous indomethacin. European Journal of Pharmaceutics and Biopharmaceutics 82:187 - 93 (2012). SOLID STATE
  227. Wu JX, Xia D, van den Berg F, Amigo JM, Rades T, Yang M, Rantanen J, A novel image analysis methodology for online monitoring of nucleation and crystal growth during solid state phase transformations. International Journal of Pharmaceutics 433: 60 - 70 (2012). SOLID STATE
  228. Bushby SK, Thomas N, Priemel PA, Coulter CV, Rades T, Kieser JA, Determination of methylphenidate in Calliphorid larvae by liquid-liquid extraction and liquid chromatography mass spectrometry – Forensic entomotoxicology using an in vivo rat brain model. Journal of Pharmaceutical and Biomedical Analysis 70: 456-461 (2012). COLLOIDAL SYSTEMS
  229. Thomas N, Holm R, Rades T, Müllertz A, Characterising lipid lipolysis and its implication in lipid-based formulation development. The AAPS Journal 14: 860 - 871 (2012). COLLOIDAL SYSTEMS
  230. Bøtker J, Rades T, Rantanen J, Hawley A, Boyd BJ, Structural elucidation of rapid solution mediated phase transitions in pharmaceutical solids using in situ synchrotron SAXS/WAXS. Molecular Pharmaceutics 9: 2787 - 2791 (2012). SOLID STATE
  231. Parmentier J, Thomas N, Müllertz A, Fricker G, Rades T, Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. International Journal of Pharmaceutics 437: 253 - 263 (2012). COLLOIDAL SYSTEMS
  232. Patel A, Gauld R, Norris P, Rades T, Quality of generic medicines in South Africa: Perceptions versus Reality - A qualitative study. BMC Health Services Research 12: 297 (2012).
  233. Ou ZQ, Schmierer DM, Rades T, Larsen L, McDowell A, Application of a post-column HPLC-DPPH assay to investigate optimal extraction of antioxidants from Sonchus oleraceus L. leaf extracts. Journal of Pharmacy and Pharmacology 65: 271-279 (2012). SOLID STATE
  234. Pongjanyakul T, Khunawattanakul W, Strachan CJ, Gordon KC, Puttipipatkhachorn S, Rades T, Characterization of chitosan-magnesium aluminum silicate nanocomposite films for buccal delivery of nicotine. International Journal of Biological Macromolecules 55: 24– 31 (2013). COLLOIDAL SYSTEMS
  235. Kanjanakawinkul W, Rades T, Puttipipatkhachorn S, Pongjanyakul T, Nicotine-magnesium aluminum silicate microparticles surface modified with chitosan for mucosal delivery. Materials Science and Engineering C 33: 1727 - 1736 (2013). COLLOIDAL SYSTEMS
  236. Thomas N, Holm R, Garmer M,  Karlsson JJ, Müllertz A, Rades T, Supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs. The AAPS Journal 15: 219 – 227 (2013). COLLOIDAL SYSTEMS
  237. Bøtker JP, Rantanen J, Rades T, Müllertz A, Østergaard J, Jensen H, A new Approach to Dissolution Testing by UV Imaging and Finite Element Simulations. Pharmaceutical Research 30: 1328 – 1337 (2013). SOLID STATE
  238. Rehder S, Wu JX, Laackmann J, Moritz HU, Rantanen J, Rades T, Leopold CS, Real-time monitoring of solid-state phase transformations in acoustically levitated particles using near infrared and Raman spectroscopy. European Journal of Pharmaceutical Sciences 48: 97 - 103 (2013). SOLID STATE
  239. Christensen NPA, Van Eerdenbrugh B, Kwok K, Taylor LS, Bond AD, Rades T, Rantanen J, Cornett C, Rapid insight into heating-induced phase transformations in the solid-state of the calcium salt of atorvastatin using multivariate data analysis. Pharmaceutical Research 30: 826 - 835(2013). SOLID STATE
  240. Rizwan SB, McBurney WT, Young K, Hanley T, Boyd BJ, Rades T, Hook S, Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses. Journal of Controlled Release 165: 16 - 21(2013). COLLOIDAL SYSTEMS
  241. Hubert M, Compton B, Hayman C, Larsen D, Painter G, Rades T, Hook S,  Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues. Molecular Pharmaceutics 10: 1928 – 1939 (2013). COLLOIDAL SYSTEMS
  242. Chaiyana W, Rades T, Okonogi S, Characterization and in vitro permeation study of microemulsions and liquid crystalline systems containing the anticholinesterase alkaloidal extract from Tabernaemontana divaricate. International Journal of Pharmaceutics 452: 201-210 (2013). COLLOIDAL SYSTEMS
  243. Thomas N, Rades T, Müllertz A, Recent developments in oral lipid-based drug delivery. Journal of Drug Delivery, Science and Technology 23: 375 – 382 (2013). COLLOIDS
  244. Grohganz H, Löbmann K, Priemel P, Tarp Jensen K, Graeser K, Strachan CS, Rades T, Amorphous drugs and dosage forms. Journal of Drug Delivery, Science and Technology 23: 403 – 408 (2013). SOLID STATE
  245. Hagner Nielsen L, Rades T, Müllertz A, Characterisation during storage and dissolution of solid dispersions containing furosemide and hydroxypropyl methylcellulose. Journal of Drug Delivery, Science and Technology 23: 409 – 415 (2013). SOLID STATE
  246. Löbmann K, Laitinen R, Grohganz H, Strachan CJ, Rades T, Gordon KC, A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin. International Journal of Pharmaceutics 453: 80 – 87 (2013). SOLID STATE
  247. Laitinen R, Löbmann K, Strachan CJ, Grohganz H, Rades T, Emerging trends in the stabilization of amorphous drugs. International Journal of Pharmaceutics 453: 65 – 79 (2013). SOLID STATE
  248. Priemel P, Laitinen R, Barthold S, Grohganz H, Lehto VP, Rades T, Strachan CJ, Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures. International Journal of Pharmaceutics 456: 301– 306 (2013).  SOLID STATE
  249. Löbmann, Laitinen R,  Strachan CJ,  Grohganz H,  Rades T,  Amino acids as co-amorphous stabilisers for poorly water soluble drugs - Part 1: Preparation, stability and dissolution enhancement. European Journal of Pharmaceutics and Biopharmaceutics 85: 873 - 881 (2013). SOLID STATE
  250. Löbmann, Laitinen R, Strachan CJ,  Rades T,  Grohganz H,  Amino acids as co-amorphous stabilisers for poorly water soluble drugs - Part 2: Molecular Interactions European Journal of Pharmaceutics and Biopharmaceutics 85: 882 - 888 (2013). SOLID STATE
  251. Scherließ R, Buske S, Young K, Weber B, Rades T, Hook S, In vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations. Vaccine 31: 4812 - 4819 (2013). COLLOIDS
  252. Haaser M, Naelapää K, Gordon KC, Pepper M, Rantanen J, Strachan CJ, Taday PF, Zeitler JA, Rades T, Evaluating the effect of coating equipment on tablet film quality using terahertz pulsed imaging. European Journal of Pharmaceutics and Biopharmaceutics 85: 1095 - 1102 (2013). SOLID STATE
  253. Priemel PA, Laitinen R, Grohganz H, Rades T, Strachan CJ, In situ amorphisation of indomethacin with Eudragit® E during dissolution. European Journal of Pharmaceutics and Biopharmaceutics 85: 1259 - 1265 (2013). SOLID STATE
  254. Hagner Nielsen L, Gordon S, Parjander JP, Østergaard J, Rades T, Müllertz A, Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution. International Journal of Pharmaceutics 457: 14 – 14 (2013). SOLID STATE
  255. Haaser M, Gordon KC, Strachan CJ, Rades T, Terahertz pulsed imaging as an advanced characterisation tool for film coatings – a review. International Journal of Pharmaceutics 457: 510 – 520 (2013). SOLID STATE
  256. Haaser M, Karrout Y, Velghe C, Cuppok Y, Gordon KC, Pepper M, Siepmann J, Rades T, Taday PF, Strachan CJ, Application of terahertz pulsed imaging to analyse film coating characteristics of sustained-release coated pellets. International Journal of Pharmaceutics 457: 521 – 526 (2013). SOLID STATE
  257. Pirayavaraporn C, Rades T, Gordon KC, Tucker IG, Quantification of the types of water in Eudragit RLPO polymer and the kinetics of water loss using FT-IR. International Journal of Pharmaceutics 458: 90 - 98 (2013). SOLID STATE
  258. Rattanapak T, Birchall JC, Young K, Ishii M, Meglinski I, Rades T, Hook S, Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using optical coherence tomography and two-photon microscopy. Journal of Controlled Release 172: 894 – 903 (2013). COLLOIDS
  259. Schwab M, McGoverin CM, Gordon KC, Winter G, Rades T, Myschik J, Strachan CJ, Studies on the lipase induced degradation of lipid based drug delivery systems. Part II - Investigations on the mechanisms leading to collapse of the lipid structure. European Journal of Pharmaceutical Sciences 84: 456 - 63 (2013). COLLOIDAL SYSTEMS
  260. Rehder S, Christensen NPA  Rantanen J, Rades T, Leopold CS, High-shear granulation as a manufacturing method for cocrystal granules. European Journal of Pharmaceutics and Biopharmaceutics 85: 1019 – 1030 (2013). SOLID STATE
  261. Bohr A, Bøtker JP, Rades T, Rantanen J, Yang M, Application of spray drying /electrospinning for poorly water soluble drugs: a particle engineering approach. Current Pharmaceutical Design 20: 325-348 (2014). SOLID STATE
  262. Wu JX, van den Berg F, Rantanen J, Rades T, Yang M, Current advances and future trends in characterizing poorly water-soluble drugs using spectroscopic, imaging and data analytical techniques. Current Pharmaceutical Design 20: 436-453 (2014). SOLID STATE
  263. Hagner Nielsen L, Keller SS, Boisen A, Müllertz A, Rades T, A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour. Drug Delivery and Translational Research (2014) IN PRESS. SOLID STATE
  264. Nielsen LH, Gordon S, Holm R, Selen A, Rades T, Müllertz A, Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats. European Journal of Pharmaceutics and Biopharmaceutics (2014) IN PRESS. SOLID STATE
  265. Munk T, Baldursdottir S,  Hietala S, Rades T, Nuopponen  M, Kalliomäki K, Tenhu H, Rantanen J, Strachan CS, Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysis. Polymer  (2014) IN PRESS. COLLOIDS
  266. Mah PT, Laaksonen T, Rades T, Aaltonen J, Peltonen L, Strachan CJ, Unravelling the relationship between degree of disorder and the dissolution behaviour of milled glibenclamide. Molecular Pharmaceutics (2014) ACCPETED. SOLID STATE
  267. Fonteyne M, Fussell AL, Vercruysse J, Vervaet C, Remon JP, Strachan CJ, Rades T, De Beer T, Distribution of binder in granules produced by means of twin screw granulation. International Journal of Pharmaceutics (2014) ACCPETED. SOLID STATE
  268. Ou ZQ, Schmierer DM, Strachan CJ, Rades T, McDowell A, Influence of postharvest processing and storage conditions on key antioxidants in pūhā (Sonchus oleraceus L.). Journal of Pharmacy and Pharmacology (2014) ACCPETED.
  269. Neumann S, Burkert K, Kemp R, Rades T, Dunbar PR, Hook S, Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants. Immunology and Cell Biology (2014) ACCPETED. COLLOIDS
  270. Feltrin KL, Brennan IM, Rades T, Horowitz M, Feinle-Bisset C, Acute oral administration of lauric acid reduces energy intake in healthy males. e-SPEN Journal (2014) ACCPETED. COLLOIDS
  271. Thomas N , Richter K, Pedersen TB, Holm R, Müllertz A, Rades T, In vitro lipolysis data does not adequately predict the in vivo performance of lipid-based drug delivery systems containing fenofibrate. AAPS Journal (2014) ACCPETED. COLLOIDS
  272.  Grohganz H, Priemel PA, Löbmann K, Hagner Nielsen L, Laitinen R, Müllertz A, Van den Mooter G, Rades T, Refining stability and dissolution rate of amorphous drug formulations. Expert Opinion in Drug Delivery (2014) ACCPETED. SOLID STATE
  273. Laitinen R, Loebmann K, Grohganz H, Strachan C, Rades T, Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability.
  274. Molecular Pharmaceutics (2014) ACCPETED. SOLID STATE
  275.  Jensen KT, Löbmann K, Rades T, Grohganz H, Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline. Pharmaceutics (2014) ACCPETED. SOLID STATE
  276. Löbmann K, Flouda K, Qiu D, Tsolakou T, Wang W, Rades T, The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin. Pharmaceutics (2014) ACCPETED. SOLID STATE
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  301.  
  302.  
  303. Michaelsen MH, Wasan KM, Sivak O, Müllertz A, Rades T, The effect of digestion and drug load on halofantrine absorption from Self-Nanoemulsifying Drug Delivery System (SNEDDS). AAPS Journal 18: 180 - 186 (2016)
  304. Khan J, Rades T, Boyd B, The precipitation behavior of poorly water-soluble drugs with an emphasis on the digestion of lipid based formulations. Pharmaceutical Research 33: 548 - 562 (2016)
  305. Jensen KT, Blaabjerg  LI, Lenz E, Bohr A, Grohganz H, Kleinebudde P, Rades T, Löbmann K, Preparation and characterization of spray dried co-amorphous drug-amino acid salts. Journal of Pharmacy and Pharmacology 68: 615 - 624 (2016)
  306. Klukkert M, Wu JX, Rantanen J, Rheder SC, Carstensen JM, Rades T, Leopold CS, Non-destructive quality control of tablets and blister packs by UV imaging. Pharmaceutical Industry 78: 108-120 (2016)
  307. Cipolla D, Wu H, Salentinig S, Boyd B, Rades T, Vanhecke D, Rothin-Rutishauser B, Eastman S, Redelmeier T, Gonda I, Chan HK, Formation of Drug Nanocrystals under Nanoconfinement Afforded by Liposomes. RCS Advances 6: 6223-6233 (2016)
  308. Boetker JP, Rantanen J, Arnfast L, Doreth M, Raijada D, Loebmann K, Madsen C, Khan J, Rades T, Müllertz M, Hawley A, Thomas D and Boyd B, Anhydrate to hydrate solid state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction. European Journal of Pharmaceutics and Biopharmaceutics 100: 119-127 (2016)
  309. Rask MB, Knopp MM, Olesen NE, Holm R, Rades T, Influence of PVP/VA copolymer composition on drug-polymer solubility. European Journal of Pharmaceutical Sciences 85: 10-17 (2016)
  310. Knopp MM, Nguyen JH, Becker C, Francke NM, Jørgensen EB, Holm P, Holm R, Mu H, Rades T, Langguth P, Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions.  European Journal of Pharmaceutics and Biopharmaceutics 101: 145-151 (2016)
  311. Tran T, Xi X, Rades T, Müllertz A, Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine.  International Journal of Pharmaceutics 502: 151-160 (2016)
  312. Mah PT, Peltonen L, Novakovic D, Rades T, Strachan CJ, Laaksonen T,
    The effect of surfactants on the dissolution behavior of amorphous formulations. European Journal of Pharmaceutical Sciences 103: 13-22 (2016)
  313. Schmidt ST, Foged C, Korsholm KS, Rades T, Christensen D, Liposome-based Adjuvants for Subunit Vaccines – Formulation Strategies for Subunit Antigens and Immunostimulators. Pharmaceutics 8 (1): 7 (2016)
  314. LH Nielsen, Melero A, Keller SS, Jacobsen J, Garrigues T, Rades T, Müllertz A, Boisen A, Polymeric microcontainers improve oral bioavailability of furosemide. International Journal of Pharmaceutics 504: (1), 98-109 (2016)
  315. Sovago I, Wang W, Qiu D, Raijada D, Rantanen R, Grohganz H, Rades T, Bond AD, Löbmann K, Properties of the sodium-naproxen-lactose-tetrahydrate co-crystal upon processing and storage. Molecules 21 (4): 509 (2016)
  316. Beyer A, Radi L, Grohganz H, Löbmann K, Rades T, Leopold CS, Preparation and recrystallization behaviour of spray-dried co-amorphous Naproxen-Indomethacin. European Journal of Pharmaceutics and Biopharmaceutics 104: 72-81 (2016)
  317. Gniado K, Löbmann K, Rades T, Erxleben A, The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems. International Journal of Pharmaceutics 504: 20 - 26 (2016)
  318. Lim AW, Löbmann K, Grohganz H, Rades T, Chieng N, Investigation of physical properties and stability of indomethacin-cimetidine and naproxen cimetidine co-amorphous systems prepared by quench cooling, co-precipitation and ball milling. Journal of Pharmacy and Pharmacology 68: 36 - 45 (2016)
  319.  Khan J, Hawley A, Rades T, Boyd BJ, In -situ lipolysis and synchrotron SAXS for the direct determination of the precipitation and solid state form of a poorly-water soluble drug during digestion of a lipid based formulation. Journal of Pharmaceutical Sciences 105: 2631 - 2639 (2016)
  320. Knopp MM, Gannon N, Porsch I, Rask MB, Olesen NE, Langguth P, Holm R, Rades T, A promising new method to estimate drug-polymer solubility at room temperature. Journal of Pharmaceutical Sciences 105: 2621 - 2624 (2016)
  321.  Andersson SBE, Alvebratt C, Bevernage J, Bonneau D, da Costa Mathews C, Dattani R, Edueng K, He Y, Holm R, Madsen C, Müller T, Muenster U, Mullertz A, Ojala K, Rades T, Sieger P, Bergström CAS, Interlaboratory validation of small scale dissolution measurements of poorly water-soluble drugs. Journal of Pharmaceutical Sciences 105: 2864 - 2872 (2016)
  322. Klukkert M, Wu JX, Rantanen J, Rheder SC, Carstensen JM, Rades T, Leopold CS, Rapid assessment of tablet film coating quality by multispectral UV imaging. AAPS PharmSciTech 17: 958 - 967 (2016)
  323. Swapnil JD, Grohganz H, Rades T, Löbmann K, Recent advances in co-amorphous drug formulations. Advanced Drug Delivery Reviews 100: 116 -125 (2016)
  324. Priemel P, Grohganz H, Rades T, Unintended and in situ amorphisation of pharmaceuticals. Advanced Drug Delivery Reviews, Advanced Drug Delivery Reviews 100: 126 - 132 (2016)
  325. Knopp MM, Löbmann K, Elder DP, Rades T, Holm R, Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development. European Journal of Pharmaceutical Sciences 87: 164 - 173 (2016)
  326. Knopp MM, Thu JH,  Mu H,  Langguth P, Rades T, Holm R, Influence of copolymer composition on in vitro and in vivo performance of celecoxib-PVP/VA amorphous solid dispersions. The AAPS Journal 18: 416 - 423 (2016)
  327. Knopp MM, Chourak N, Khan F, Wendelboe J,  Langguth P, Rades T, Holm R, Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions. European Journal of Pharmaceutics and Biopharmaceutics 105: 106 - 114 (2016)
  328. Klukkert M, Wu JX, Rantanen J, Carstensen JM, Rades T, Leopold CS, Multispectral UV Imaging for fast and non-destructive quality control of chemical and physical tablet attributes. European Journal of Pharmaceutical Science 90: 85 - 95 (2016)
  329. Jensen KT, Larsen FH, Löbmann K, Rades T, Grohganz H, Influence of variation in molar ratio on co-amorphous drug-amino acid systems. European Journal of Pharmaceutics and Biopharmaceutics 107: 32 - 39 (2016)
  330. Blaabjerg L, Lindenberg E, Loebmann K, Grohganz H, Rades T, Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation. Molecular Pharmaceutics 13: 3318 - 3325 (2016)
  331. Sassene PJ, Fanø M, Mu H, Rades T, Aquistapace S, Schmitt B, Cruz-Hernandez C, Woosterc TJ, A. Müllertz A, Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates. Food & Function 7: 3989 - 3998 (2016)
  332. Schmidt ST, Khadke S, Smith Korsholm K, Perrie Y, Rades T, Andersen P, Foged C, Christensen D, The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8+ T-cell responses: The immunological consequences of the biodistribution profile. Journal of Controlled Release 239: 107 - 117 (2016)
  333. Klodzinska SN, Priemel PA, Rades T, Mørck Nielsen HM, Inhalable antimicrobials for treatment of bacterial biofilm-associated sinusitis in cystic fibrosis patients: challenges and drug delivery approaches. International Journal of Molecular Sciences 17: 10, 1688; doi: 10.3390/ijms17101688 (2016)
  334. Sassene P, Michaelsen M, Mosgaard M, Jensen M, Van Den Broek E, Wasan K,  Mu H, Rades T, Müllertz A, In vivo precipitation of poorly soluble drugs from lipid based drug delivery systems. Molecular Pharmaceutics13: 3417 - 3426 (2016)
  335. Beyer A, Grohganz H, Löbmann K, Rades T, Leopold CS, Influence oft he cooling rate and the blend ratio on the physical stability of co-amorphous naproxen/indomethacin. European Journal of Pharmaceutics and Biopharmaceutics 109: 140 - 148 (2016)
  336. Novikova A, Carstensen JM, Rades T, Leopold CS, Multispectral UV imaging for surface analysis of MUPS tablets with special focus on the pellet distribution. International Journal of Pharmaceutics 515: 374 - 383 (2016)
  337. Knopp MM, Olesen NE, Huang Y, Holm R, Rades T,  Statistical analysis of a method to predict drug-polymer miscibility. Journal of Pharmaceutical Sciences 105: 362 - 367 (2016)
  338. Kasten G, Grohganz H, Rades T, Löbmann K, Development of a screening method for co-amorphous formulations of drugs and amino acids. European Journal of Pharmaceutical Sciences 95: 28 - 35 (2016)
  339. 339. Doreth M, Hussein MA, Priemel PA, Grohganz H, Holm R, De Diego HL, Rades T, Löbmann K. Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ. International Journal of Pharmaceutics 519: 343 - 351 (2017)
  340. Lenz E, Löbmann K, Rades T, Knopp K, Kleinebudde P, Hot melt extrusion and spray drying of co-amorphous indomethacin-arginine with polymers. Journal of Pharmaceutical Sciences 106: 302 - 312 (2017)
  341. Blaabjerg LI, Lindenberg E, Rades T, Grohganz H, Löbmann K,  Influence of preparation pathway on the glass forming ability. International Journal of Pharmaceutics 521: 232 - 238 (2017)
  342. Jensen LG, Skautrup FB, Müllertz A, Abrahamsson B, Rades T, Priemel PA, Amorphous is not always better – a dissolution study on solid state forms of carbamazepine. International Journal of Pharmaceutics 522: 74 - 79 (2017)
  343. Mosgaard MD, Sassene P, Mu H, Rades T, Müllertz A, Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems. Journal of Pharmaceutical Sciences 106: 1183 - 1186 (2017)

 Professional journal articles

  1. Rades T, Formulation and drug delivery group. New Zealand Biotechnology Association Newsletter 32: 43 - 47 (1996).
  2. Rades T, Ointments, creams, gels and pastes - Classification of semi-solid preparations. New Zealand Pharmacy 17: 31 - 33 (1997).
  3. Rades T, Freeze fracturing of hot samples. Microscopy in Focus 2: 12 - 14 (1997).
  4. Rades T, Freeze fracturing of hot samples. Microscopy Today 97 (6): 14 (1997) (reprint of 3.).
  5. Rades T, Hot stage polarising light microscopy of thermotropic liquid crystals. Microscopy in Focus 3: 10 - 12 (1998).
  6. Rades T, Unnikrishnan MK, Pharmaceutical education in Germany. Indian Journal of Pharmaceutical Education 32 (2): 101 - 103, (1998).
  7. Fawcett JP, Rades T, Practice and science in education. British Pharmaceutical Journal 260: 552 (1998).
  8. Rades T, Davies N, Faas H, Gamma-scintigraphy and Magnetic Resonance Imaging. New Zealand Pharmacy 20 (4): 31 - 33 (2000).
  9. Baird M, Copland M, Davies N, Rades T, Dendritic cells, sentinels of the immune system. New Zealand Pharmacy 20 (7): 30 - 31 (2000).
  10. Davies N, Rades T, Liposomes/microemulsions - Sophisticated drug delivery systems appearing on the market. New Zealand Pharmacy 20 (10): 32 - 34 (2000).
  11. Rades T, Davies N, Nanosystems for the oral delivery of proteins and peptides. New Zealand Pharmacy 21 (5): 30 - 31 (2001).
  12. Rades T, Report on the second conference of the New Zealand Chapter of CRS Controlled Release Newsletter 19 (2): 22 (2002).
  13. Rades T, Davies N, Nanoparticulate systems for the delivery of bioactives. New Zealand Journal Biotechnology Association Journal 53: 33 - 36 (2002).
  14. Gordon K, Rades T, Spectroscopy and solid state properties of drugs: Will femtochemistry meet pharmacy? Chemistry in New Zealand, 11/02: 43 - 47 (2002).
  15. Rades T, Drugs and drug delivery systems at the 8th International Pacific Rim Biotechnology Conference. New Zealand Biotechnology Association Journal 55: 33 - 35 (2003).
  16. Rades T, Davies N, Nanoparticulate delivery systems for bioactives. Newsletter of the New Zealand Chapter of the Controlled Release Society 2: 3 - 4 (2003).
  17. Rades T, Nanoparticles for bioactive delivery. Newsletter of the Australasian Pharmaceutical Science Association http://www.apsa-online.org (2003).
  18. Zeitler JA, Rades T,  Polymorphe Arzneistoffe - Genauerer Blick dank Terahertz-Strahlen. Pharmazeutische Zeitung 150: 4586 (2005).
  19. Zeitler JA, Taday PF, Rades T, Terahertz pulsed-imaging – a unique novel tool for the characterisation of controlled release dosage forms. Controlled Release Society Newsletter 23 (2): 7 - 9 (2006).
  20. Sandler N, Tian F, Rades T, Screening for excipients – probing polymorphic phase transformations by Raman spectroscopy. Screening - Trends in Drug Discovery 3: 3 - 35 (2006).
  21. Ho L, Zeitler JA, Strachan CJ, Gordon KC, Rades T, Terahertz pulsed spectroscopy – potential for analysis of pharmaceutical ingredients. G.I.T. Laboratory Journal 5: 12 – 13 (2006).
  22. Jones DS, Rades T, Applications of novel spectroscopic techniques to pharmaceutical systems. Journal of Pharmacy and Pharmacology 59: 145 – 146 (2007).
  23. McDowell A, McLeod B, Rades T, Tucker I, Designing delivery systems for wildlife applications – the brushtail possum. Controlled Release Society Newsletter 24 (1): 13 - 14 (2007).  
  24. 24. Ho L, Gordon KC, Rades T, Taday P, Terahertz pulsed imaging: A potential process analytical tool for tablet coating qualities. Pharmaceutical Formulation and Quality April/May Edition: 48 – 52 (2007).
  25. Rizwan SB, Girwan L, Boyd BJ, Rades T, Hook S, Using cryofield emission scanning electron microscopy (cryo FESM) to examine the unique microstructure of bicontinuous liquid crystalline system of phytantriol and water.  Microscopy in Focus 17: 13 - 17 (2007).
  26. Tantipolphan R, Rades T, Medlicott NJ, Swellable lipid implants: Use of vibrational spectroscopy to study lipid and protein structure. Controlled Release Society Newsletter 24 (4): 14 - 16 (2007).
  27. Kafka AP, Kleffmann T, Rades T, McDowell A.  Co-polymerization of D-Lys6-GnRH in PACA nanoparticles: Revealed by MALDI-TOF.  Controlled Release Society Newsletter 26(4): 15 - 17 (2009).
  28. Perrie Y, Rades T, Themed issue: Improve dissolution, solubility and bioavailability of poorly soluble drugs Journal of Pharmacy and Pharmacology 62: 1517–1518 (2010).
  29. Rades T, Perrie Y, Editorial: Advanced Characterisation Techniques - Themed issue. International Journal of Pharmaceutics 417: 1– 2 (2011).
  30. Rizwan SB, Boyd BJ, Rades T, Hook S, Cubosomes containing imiquimod and monophosphoryl lipid A stimulate enhanced cellular responses compared to allum. CRS  Newsletter 29(5): 12 - 14 (2012).
  31. Löbmann K, Tarp Jensen K, Grohganz H, Rades T, Ordnung muss (nicht) sein! Lægemiddelforskning 2012: 34 – 36 (2012).
  32. N Thomas, R Holm, T Rades, A Müllertz, Ny metode skal øge biotilgængeligheden af lægemiddelstoffer: Overmætning i kapsler eller i tarmen Lægemiddelforskning 2012: 37 – 39 (2012).

 

 Significant Conference Involvement

2012, Co-organiser and Session Chair of  the Fourteenth International Workshop on Physical Characterization of Pharmaceutical Solids  (IWPCPS XIII), Advanced Solid State Analysis (ASSA), Barcelona, Spain, June 2012

  • 2012, Main organiser, programme and session chair of the 14th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2012.
  • 2011, Co-organiser and Session Chair of  the Thirteenth International Workshop on Physical Characterization of Pharmaceutical Solids  (IWPCPS XIII), Advanced Solid State Analysis (ASSA), Indianapolis, USA, June 2011.
  • 2011, Main organiser, programme and session chair of the 13th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2011.
  • 2010, Co-organiser, programme and session chair of the 12th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2010.
  • 2009, Co-organiser and Session Chair of  the Twelfth International Workshop on Physical Characterization of Pharmaceutical Solids  (IWPCPS XII), Advanced Solid State Analysis (ASSA), Lille, France, June 2010.
  • 2009, Co-organiser, programme and session chair of the 11th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2009.
  • 2009, Co-organiser and Session Chair of  the Eleventh International Workshop on Physical Characterization of Pharmaceutical Solids  (IWPCPS XI), Advanced Solid State Analysis (ASSA), Stamford, Ct, USA, June 2009.
  • 2008, Co-organiser of  the Workshop: Vaccine formulation: the key to success, 7th Biannual Conference of  the Globalization Of Pharmaceutics Education Network (GPEN), Leuven, Belgium, September 2008.
  • 2008, Member of the Scientific & Planning Committee of the EUFEPS Workshop Opportunities and Challenges in Vaccine Delivery, University of Geneva, Site d’Archamps, France, September 2008
  • 2008, Co-organiser of CRS Workshop Strategies to Advance the Bioavailability of Low Solubility Drugs, Controlled Release Society (CRS), New York, USA, July 2008.
  • 2008, Co-organiser and Session Chair of  Tenth International Workshop on Physical Characterization of Pharmaceutical Solids  (IWPCPS X), Advanced Solid State Analysis (ASSA), Bamberg, Germany, June 2008.
  • 2008, Co-organiser, programme and session chair of the 10th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2008.
  • 2007, Co-organiser and session chair of the 9th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2007.
  • 2006, Co-organiser and session chair of the APSA Conference, Adelaide, South Australia, Australia, December 2006.
  • 2006, Workshop organiser at the Spotlight on Teaching Colloquium, University of Otago, Dunedin, New Zealand, February 2007.
  • 2006, Co-organiser and session chair of the 8th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, February 2006.
  • 2005, Co-organiser and session chair of the APSA/ASCEPT Conference, Melbourne, Australia, December 2005.
  • 2005, Session organiser of ChemEd Conference (New Zealand Association of Science Educators) July 2005, Dunedin
  • 2005, Co-organiser and session chair of the 7th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, 17th - 18th February 2005.
  • 2004, Co-organiser and session chair of the Lasers and Applications Research Theme meeting, University of Otago, Dunedin, New Zealand, 18th November 2004.
  • 2004, Co-organiser and session chair of the APSA Conference, Melbourne, Australia, December 2004.
  • 2004, Co-organiser and session chair of the 6th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, 12th - 13th February 2004
  • 2003, Co-organiser and session chair of the APSA Conference, Sydney, Australia, December 2003.
  • 2003, Co-organiser and session chair of the CRS-New Zealand Local Chapter Workshop: "Controlled release products - development and regulatory issues", Auckland, New Zealand, November 2003.
  • 2002, Session chair of Podium Session I (Drug Delivery Systems) at the Annual Conference of the Australasian Pharmaceutical Society Association, APSA, Melbourne, Australia, 8th - 11th of December 2002.
  • 2002, Co-organiser and session chair of the Drug Delivery Session at the 8th International Pacific Rim Biotechnology Conference, Biotenz and NZBA, Auckland, New Zealand, 17th - 20th of November 2002
  • 2002, Co-organiser and session chair of the 5th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, 20th and 21st February 2002
  • 2001, Co-organiser and session chair of the 4th Formulation and Delivery of Bioactives Conference, University of Otago, Dunedin, New Zealand, 15th and 16th February 2001
  • 2000, Co-organiser and session chair of the 3rd Formulation and Drug Delivery Conference, University of Otago, Dunedin, New Zealand, 2nd and 3rd February 2000

   

 Patents

  • Ho, L; Shen, YC; Taday, PF; Rades T: Analysis apparatus and method. UK Application Number: 0701646.2, Publication Number: GB2446026 (A8) (2008)
  • Taday, PF; Shen, YC; Ho, L; Rades T: A pharmaceutical analysis method and apparatus.  UK Application Number: 0712397.9, Publication Number: GB2446166 (A8) (2008)
  • Ho, L; Shen, YC; Taday, PF; Rades T: Analysis apparatus and method. International Application Number: PCT/GB208/00293, International Publication Number: WO2008/093067 A1 (2008)
  • Lee C, Rawle C, Strachan C, Rades T, Manson P, Payne C: Method and apparatus for performing a second order non-linear optical  measurement on a sample. NZ Patent App. No: 537184 (2004)
  • Feinle, C, Fried, M, Lengsfeld H, Rades T: Pharmaceutical composition and method for treatment of dyspepsia US Patent 6,534,539 (2003)
  • Feinle, C, Fried, M, Lengsfeld H, Rades T: Use of lipase inhibitors European Patent EP 00117088.5 (2000)
  • Hadvary P, Lengsfeld H, Rades T, DeSmidt PC, Steffen H, Tardio J: Pharmaceutical compositions containing lipase inhibitors European Patent EP 99118180.1 (1999)
  • Alex, R; Gerhards, J; Krämer-Pittrof, I; Oeschger, R; Rades, T: Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses US Patent 6,352,717 (1999)
  • Alex, R; Gerhards, J; Krämer-Pittrof, I; Oeschger, R; Rades, T: Process for the manufacture of liquid filled capsules. European Patent EP 98121831.6 (1998)
  •  

Professional Activities

 Service to External Academic and Professional Activities

  • Member of the Scientific and Planning Committee of the 2nd Electronic Conference on Pharmaceutical Sciences, May 1-31, 2012 Electronic conference at http://www.sciforum.net/conf/ecps, 2012
  • Member of the Member of the CRS Jorge Heller Journal of Controlled Release Outstanding Paper Award, Controlled Release Society, 2012
  • Member of the Member of the CRS Jorge Heller Journal of Controlled Release Outstanding Paper Award, Controlled Release Society, 2011
  • Member of the Scientific and Planning Committee of the 1st Electronic Conference on Pharmaceutical Sciences, March 1-31, 2011 Electronic conference at http://www.sciforum.net/conf/ecps2011
  • Symposium organizer of the Twelfth International Workshop on Physical Characterization of Pharmaceutical Solids, Solid State Characterisation Methods and Physical Stability of API Dispersions, Lille, France, June, 2010
  • Co-organiser and presenter at the APS workshop: Poorly soluble drugs: How can we improve dissolution, solubility and bioavailability, Aston, Birmingham, United Kingdom, August, 2009
  • Symposium organizer of the Eleventh International Workshop on Physical Characterization of Pharmaceutical Solids, Detecting Process Induced Transformations in Solid State Formulations, Stamford, Ct, USA, June, 2009
  • Co-organiser and presenter at the CRS-New Zealand workshop: Peptide and Protein Bioactives – Stability and Delivery, Dunedin, New Zealand, October, 2008
  • Co-organiser and presenter at the CRS-Australia workshop: Peptide and Protein Bioactives – Stability and Delivery, Brisbane, Queensland, Australia, October, 2008
  • Member of the Scientific and Planning Committee of the EUFEPS workshop: Opportunities and Challenges in Vaccine Delivery, Geneva, Switzerland, August 2008
  • Co-organiser and workshop chair of the CRS workshop: Strategies to Advance the Bioavailability of Low Solubility Drugs, New York, NY, USA, July, 2008
  • Member of Organising Committee and Symposium organizer of the Tenth International Workshop on Physical Characterization of Pharmaceutical Solids, Bamberg, Germany, May, 2008
  • Scientific Advisor to the International Foundation for Science (IFS), Stockholm, Sweden, 2008
  • External Advisor for the MSc Pharmaceutical Sciences Programme at Aston University, Birmingham. UK, July 2007
  • Member of the International Advisory Committee of the International Conference on Perspectives in Vibrational Spectroscopy, Trivendrum, India, February 2008
  • Member of Organising Committee and Symposium organizer of the Ninth International Workshop on Physical Characterization of Pharmaceutical Solids, Boston, Massachusetts, USA, May, 2007
  • Member of Organising Committee and Symposium organizer of the First International Workshop on the Pharmaceutical Physical Characterization of the Amorphous State, Stamford, CT, USA, May, 2006
  • Member of the International Advisory Board of the 5th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Geneva, Switzerland, March 2006
  • Member of the International Advisory Committee of the International Conference on Perspectives in Vibrational Spectroscopy, Meerut, India, February 2006
  • Member of the Scientific Advisory Committee of the Joint APSA/ASCEPT Meeting, Melbourne, December, 2005
  • Symposium organizer of the Annual Conference of the Australasian Pharmaceutical Science Association (APSA), Melbourne, 2004
  • Member of the Scientific Advisory Board of the Physical Chemistry of Biointerfaces Meeting in the Barossa Valley, 2004
  • Member of the Organizing Committee and Symposium organizer of the Annual Conference of the Australasian Pharmaceutical Science Association (APSA), Bondi Beach, 2003
  • Member of the Organizing Committee of the Annual Dunedin Conference on Formulation and Delivery of Bioactives (FDB), Dunedin, 1998 – 2011
  • Editor of European Journal of Pharmaceutis and Biopharmaceutics, 2012 – present
  • Editor of Journal of Pharmaceutical Sciences, 2011 – present
  • Associate Editor of Journal of Pharmacy and Pharmacology, 2009 - present
  • Associate Editor of Journal of Pharmaceutical Sciences, 2008 – 2010
  • Member of the Editorial Board of the MrethodX, 2014 - present
  • Member of the Editorial Board of the Journal of Biomaterials Applications, 2011 - present
  • Member of the Editorial Board of International Journal of Pharmaceutics, 2010 - present
  • Member of the Editorial Board of Pharmaceutics, 2009 - present
  • Member of the Editorial Board of Pharmaceuticals, 2009 - present
  • Member of the Editorial Board of Current Drug Delivery, 2009 - present
  • Member of the Editorial Board of Journal of Liposome Research, 2009 - present
  • Member of the Editorial Board of Journal of Pharmaceutical Sciences, 2007 - 2008
  • Member of the Editorial Board of Journal of Biomaterials Science, Polymer Edition, 2007 - present
  • Member of the Editorial Board of Pharmaceutical Technology Asia, 2007 - present
  • Member of the Editorial Board of Pharmaceutical Technology Europe, 2007 - present
  • Member of the Editorial Board of the Journal of Controlled Release, 2006 - present
  • Member of the Editorial Board of DiePharmazie, 2003 - present
  • Member of the Editorial Board of the Journal of Pharmacy and Pharmacology, 2002 - 2008

 Reviewer for international scientific peer reviewed journals:

  1. AAPS Pharmaceutical Science and Technology
  2. Analytica Chimica Acta
  3. Chemical & Process Engineering
  4. Colloids & Surfaces B
  5. Current Drug Delivery
  6. Current Pharmaceutical Analysis
  7. Die Pharmazie
  8. European Journal of Pharmaceutical Sciences
  9. European Journal of Pharmaceutics and Biopharmaceutics
  10. Expert Opinion on Drug Delivery
  11. International Journal of Pharmaceutics
  12. International Journal of Nanomedicine
  13. Journal of Controlled Release
  14. Journal of Drug Delivery Science and Technology
  15. Journal of Drug Targeting
  16. Journal of Liposome Research
  17. Journal of Pharmacy and Pharmacology
  18. Journal of Pharmacy Practice and Research
  19. Journal of Pharmaceutical and Biomedical Analysis
  20. Journal of Pharmaceutical Innovation
  21. Journal of Pharmaceutical Sciences
  22. Journal of Physical Chemistry
  23. Journal of Raman Spectroscopy
  24. Journal of the Royal Society: Interface
  25. Nanomedicine: Nanotechnology, Biology and Medicine
  26.  Pharmaceutical Development and Technology
  27.  Pharmaceutical Research
  28. Pharmaceutical Technology Europe
  29.  Pharmaceutics
  30.  harmaceuticals
  31. Polymer Bulletin
  32. Talanta
  33. The Biophysical Journal

 

Referee for the NZ Association of Scientists Marsden and Shorland Medals, 2002.
Referee for the Cancer Council Victoria, Australia, 2002 – present
Referee for the Australian Competitive Grant Development Scheme, University of South Australia, Australia, 2005
Vice President of the New Zealand Chapter of the International Controlled Release Society, 2000 – 2004
President of the New Zealand Chapter of the International Controlled Release Society, 2004 - present
Member of the Executive Committee of the Australasian Pharmaceutical Science Association (APSA), 2000 – 2005

 

Education

Prof. Dr. Dr. h.c.

ID: 38132533